Soluble CD163 and mannose receptor associate with chronic hepatitis B activity and fibrosis and decline with treatment

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Journal of Gastroenterology and Hepatology

• Publication date

  2018-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/jgh.13849PMID 28618015
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The macrophage activation marker sCD163 combined with markers of the Enhanced Liver Fibrosis (ELF) score predicts clinically significant portal hypertension in patients with cirrhosis

  2016cited by this paper
• Fibrosis is not just fibrosis – basement membrane modelling and collagen metabolism differs between hepatitis B‐ and C‐induced injury

  2016cited by this paper
• Soluble CD163 is an indicator of liver inflammation and fibrosis in patients chronically infected with the hepatitis B virus

  2015cited by this paper
• The role of Kupffer cells in hepatitis B and hepatitis C virus infections.

  2014cited by this paper
• Soluble CD163, a macrophage activation marker, is independently associated with fibrosis in patients with chronic viral hepatitis B and C

  2014cited by this paper
• Hepatic Macrophage Activation and the LPS Pathway in Patients With Alcoholic Hepatitis: A Prospective Cohort Study

  2014cited by this paper
• Toll‐like receptor‐mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen

  2014cited by this paper
• Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages

  2014cited by this paper
• Non‐invasive algorithm of enhanced liver fibrosis and liver stiffness measurement with transient elastography for advanced liver fibrosis in chronic hepatitis B

  2014cited by this paper
• Hepatitis B flares in chronic hepatitis B: pathogenesis, natural course, and management.

  2014cited by this paper
• Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin.

  2013cited by this paper
• Macrophage-related serum biomarkers soluble CD163 (sCD163) and soluble mannose receptor (sMR) to differentiate mild liver fibrosis from cirrhosis in patients with chronic hepatitis C: a pilot study

  2013cited by this paper
• Relationship between Kuppfer cells, inflammation, and fibrosis in chronic hepatitis B and C.

  2013cited by this paper
• A soluble form of the macrophage-related mannose receptor (MR/CD206) is present in human serum and elevated in critical illness

  2013cited by this paper
• Soluble CD163

  2012cited by this paper
• The mannose receptor

  2012cited by this paper
• In Vitro Generation of Monocyte-Derived Macrophages under Serum-Free Conditions Improves Their Tumor Promoting Functions

  2012cited by this paper
• Soluble CD163, a marker of Kupffer cell activation, is related to portal hypertension in patients with liver cirrhosis

  2012cited by this paper
• On-Treatment Monitoring of Liver Fibrosis with Transient Elastography in Chronic Hepatitis B Patients

  2011cited by this paper
• Fungal Recognition Enhances Mannose Receptor Shedding through Dectin-1 Engagement

  2011cited by this paper
• Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection.

  2011cited by this paper
• Hyper-Activated Pro-Inflammatory CD16+ Monocytes Correlate with the Severity of Liver Injury and Fibrosis in Patients with Chronic Hepatitis B

  2011cited by this paper
• Macrophages: Master Regulators of Inflammation and Fibrosis

  2010cited by this paper
• Tumor necrosis factor -converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163

  2010cited by this paper
• Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis

  2009cited by this paper
• Soluble CD163 from activated macrophages predicts mortality in acute liver failure.

  2007cited by this paper
• High mobility group box 1 protein interacts with multiple Toll-like receptors.

  2006cited by this paper
• Cytokine Induction by the Hepatitis B Virus Capsid in Macrophages Is Facilitated by Membrane Heparan Sulfate and Involves TLR2

  2005cited by this paper
• Bacterial DNA induces a proinflammatory immune response in patients with decompensated cirrhosis.

  2005cited by this paper
• Liver histology of Asian patients with chronic hepatitis B on prolonged lamivudine therapy

  2005cited by this paper
• Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair.

  2005cited by this paper
• Expression of CD163 in the liver of patients with viral hepatitis.

  2005cited by this paper
• Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats.

  2005cited by this paper
• Impact of interferon‐alpha therapy on liver fibrosis progression in patients with HBeAg‐negative chronic hepatitis B

  2005cited by this paper
• Pneumocystis Activates Human Alveolar Macrophage NF-κB Signaling through Mannose Receptors

  2004cited by this paper
• Soluble CD163 in patients with liver diseases: very high levels of soluble CD163 in patients with fulminant hepatic failure

  2004cited by this paper
• Receptor Requirement for the Human Mannose Human Immunodeficiency Virus Type 1 : CD 4-Independent Infection of Astrocytes by

  2003cited by this paper
• Hepatitis C virus and liver disease: Global transcriptional profiling and identification of potential markers

  2003cited by this paper
• Endotoxin induces rapid metalloproteinase‐mediated shedding followed by up‐regulation of the monocyte hemoglobin scavenger receptor CD163

  2002cited by this paper
• Characterization of an enzyme-linked immunosorbent assay for soluble CD163

  2002cited by this paper
• Roles of TGF-beta in hepatic fibrosis.

  2002cited by this paper
• Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

  2001cited by this paper
• Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells.

  1989cited by this paper
• Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis

  1981cited by this paper
• Edinburgh Research Explorer Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

  year unknowncited by this paper

• Enzyme-catalyzed synthesis of mannose ester and its enhancement of tanshinone and glycyrrhetinic acid lipid nanoparticles

  2025cites this paper
• Clinical Significance of Evaluation of Monocytic Receptors in Patients with Hepatitis C Virus Infection

  2023cites this paper
• The association between soluble CD163, disease severity, and ursodiol treatment in patients with primary biliary cholangitis

  2023cites this paper
• Obese Patients With Nonalcoholic Fatty Liver Disease Have an Increase in Soluble Plasma CD163 and a Concurrent Decrease in Hepatic Expression of CD163

  2023cites this paper
• Soluble CD163 and CD163 Expression on Monocytes Associated with Chronic Hepatitis B Inflammation and HBsAg Loss

  2022cites this paper
• Increased Serum Levels of sCD206 Are Associated with Adverse Prognosis in Patients with HBV-Related Decompensated Cirrhosis

  2022cites this paper
• Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response

  2022cites this paper
• Macrophage Activation Markers, Soluble CD163 and Mannose Receptor, in Liver Fibrosis

  2021cites this paper
• Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis

  2021cites this paper
• Diagnostic value of monocyte chemoattractant Protein-1, soluble mannose receptor, Presepsin, and Procalcitonin in critically ill children admitted with suspected sepsis

  2021cites this paper
• Divergences in Macrophage Activation Markers Soluble CD163 and Mannose Receptor in Patients With Non-cirrhotic and Cirrhotic Portal Hypertension

  2021cites this paper
• Liver-related effects of chronic hepatitis C antiviral treatment

  2020cites this paper
• Activated Hepatic Stellate Cells Induce Infiltration and Formation of CD163+ Macrophages via CCL2/CCR2 Pathway

  2020cites this paper
• High CD163 Expression on Classical Monocytes Is Associated with Immune Control of HBV Infection in Noncirrhotic Patients

  2020influential citation
• Soluble CD163 and mannose receptor as markers of liver disease severity and prognosis in patients with primary biliary cholangitis

  2020cites this paper
• Macrophage Activation Markers, CD163 and CD206, in Acute-on-Chronic Liver Failure

  2020influential citation
• Improved prediction of mortality by combinations of inflammatory markers and standard clinical scores in patients with acute‐on‐chronic liver failure and acute decompensation

  2020cites this paper
• The macrophage activation marker soluble CD163 is elevated and associated with liver disease phenotype in patients with Wilson’s disease

  2020cites this paper
• Liver Macrophages: Old Dogmas and New Insights

  2019cites this paper
• Circulating CD14+CD163+CD209+ M2‐like monocytes are associated with the severity of infection in Helicobacter pylori‐positive patients

  2019cites this paper
• Soluble CD163 as a surrogate marker of fibrosis regression in chronic HCV patients receiving direct antiviral agents

  2019cites this paper
• The macrophage‐related biomarkers sCD163 and sCD206 are released by different shedding mechanisms

  2019cites this paper
• Soluble mannose receptor as a predictor of prognosis of hepatitis B virus-related acute-on-chronic liver failure

  2019cites this paper
• Rapid and persistent decline in soluble CD163 with successful direct-acting antiviral therapy and associations with chronic hepatitis C histology

  2018cites this paper
• No effect of rifaximin on soluble CD163, mannose receptor or type III and IV neoepitope collagen markers in decompensated cirrhosis: Results from a randomized, placebo controlled trial

  2018cites this paper