The SUD1 Gene Encodes a Putative E3 Ubiquitin Ligase and Is a Positive Regulator of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Arabidopsis[C][W]

No abstract is available for this paper.

• Publication year

  2013

• Venue

  The Plant Cell

• Publication date

  2013-02-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1105/tpc.112.108696PMID 23404890PMCID PMC3608789
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Arabidopsis ECERIFERUM9 Involvement in Cuticle Formation and Maintenance of Plant Water Status1[W][OA]

  2012influential reference
• Isoprenoid biosynthesis is required for miRNA function and affects membrane association of ARGONAUTE 1 in Arabidopsis

  2012influential reference
• A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?

  2012cited by this paper
• An Unusual Transmembrane Helix in the Endoplasmic Reticulum Ubiquitin Ligase Doa10 Modulates Degradation of Its Cognate E2 Enzyme*

  2011influential reference
• Multilevel Control of Arabidopsis 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase by Protein Phosphatase 2A[W]

  2011cited by this paper
• Terpene Specialized Metabolism in Arabidopsis thaliana

  2011cited by this paper
• Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

  2011cited by this paper
• The Sterol-sensing Domain (SSD) Directly Mediates Signal-regulated Endoplasmic Reticulum-associated Degradation (ERAD) of 3-Hydroxy-3-methylglutaryl (HMG)-CoA Reductase Isozyme Hmg2*

  2011cited by this paper
• Sterol and Steroid Biosynthesis and Metabolism in Plants and Microorganisms

  2010cited by this paper
• The Sterol Methyltransferases SMT 1 , SMT 2 , and SMT 3 Influence Arabidopsis Development through Nonbrassinosteroid Products 1 [ W ] [ OA ]

  2010cited by this paper
• Pleiotropic regulatory locus 1 (PRL1) integrates the regulation of sugar responses with isoprenoid metabolism in Arabidopsis.

  2010cited by this paper
• The Sterol Methyltransferases SMT1, SMT2, and SMT3 Influence Arabidopsis Development through Nonbrassinosteroid Products1[W][OA]

  2010cited by this paper
• Plant phenotypic plasticity in a changing climate.

  2010cited by this paper
• Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.

  2010cited by this paper
• Structural basis of Na+-independent and cooperative substrate/product antiport in CaiT

  2010cited by this paper
• The Sequence Alignment/Map format and SAMtools

  2009cited by this paper
• Structure and Mechanism of an Amino Acid Antiporter

  2009cited by this paper
• PLAZA: A Comparative Genomics Resource to Study Gene and Genome Evolution in Plants[W]

  2009influential reference
• Involvement of the Phospholipid Sterol Acyltransferase1 in Plant Sterol Homeostasis and Leaf Senescence1[W]

  2009cited by this paper
• Identification of the Arabidopsis dry2/sqe1-5 mutant reveals a central role for sterols in drought tolerance and regulation of reactive oxygen species.

  2009influential reference
• Cellular processes relying on sterol function in plants.

  2009cited by this paper
• Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast*

  2009cited by this paper
• Complete blockage of the mevalonate pathway results in male gametophyte lethality

  2009cited by this paper
• Arabidopsis 3-hydroxy-3-methylglutaryl-CoA reductase is regulated at the post-translational level in response to alterations of the sphingolipid and the sterol biosynthetic pathways.

  2009influential reference
• One step at a time: endoplasmic reticulum-associated degradation

  2008cited by this paper
• Allelic mutant series reveal distinct functions for Arabidopsis cycloartenol synthase 1 in cell viability and plastid biogenesis

  2008cited by this paper
• Characterization of Arabidopsis and Rice DWD Proteins and Their Roles as Substrate Receptors for CUL4-RING E3 Ubiquitin Ligases[W]

  2008cited by this paper
• Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity

  2008cited by this paper
• Arabidopsis thaliana Squalene Epoxidase 1 Is Essential for Root and Seed Development*

  2007influential reference
• Protein sensors for membrane sterols.

  2006cited by this paper
• Genetic analysis.

  2006cited by this paper
• Membrane Topology of the Yeast Endoplasmic Reticulum-localized Ubiquitin Ligase Doa10 and Comparison with Its Human Ortholog TEB4 (MARCH-VI)*

  2006influential reference
• Biosynthetic diversity in plant triterpene cyclization.

  2006cited by this paper
• Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

  2006cited by this paper
• Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.

  2006cited by this paper
• Functional Analysis of the RING-Type Ubiquitin Ligase Family of Arabidopsis1[w]

  2005influential reference
• Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

  2005cited by this paper
• A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells

  2005cited by this paper
• Biogenesis, molecular regulation and function of plant isoprenoids.

  2005cited by this paper
• Subcellular Localization of Arabidopsis 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase1

  2005cited by this paper
• TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum.

  2005cited by this paper
• Novel eceriferum mutants in Arabidopsis thaliana

  2004cited by this paper
• Theoretical and practical advances in genome halving

  2004cited by this paper
• A link between sterol biosynthesis, the cell wall, and cellulose in Arabidopsis.

  2004influential reference
• The metabolic imbalance underlying lesion formation in Arabidopsis thaliana overexpressing farnesyl diphosphate synthase (isoform 1S) leads to oxidative stress and is triggered by the developmental decline of endogenous HMGR activity

  2004influential reference
• Biosynthesis and accumulation of sterols.

  2004cited by this paper
• Distinct Light-Mediated Pathways Regulate the Biosynthesis and Exchange of Isoprenoid Precursors during Arabidopsis Seedling Development Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.016204.

  2004cited by this paper
• Loss of function of 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) in Arabidopsis leads to dwarfing, early senescence and male sterility, and reduced sterol levels.

  2004cited by this paper
• Cell Polarity and PIN Protein Positioning in Arabidopsis Require STEROL METHYLTRANSFERASE1 Function Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.008433.

  2003cited by this paper
• Non-traditional Functions of Ubiquitin and Ubiquitin-binding Proteins*

  2003cited by this paper
• ER-associated degradation in protein quality control and cellular regulation.

  2002cited by this paper
• Arabidopsis Mutants Reveal Multiple Roles for Sterols in Plant Development

  2002cited by this paper
• Inhibition of Squalene Synthase and Squalene Epoxidase in Tobacco Cells Triggers an Up-Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase

  2002influential reference
• Elucidation of the Methylerythritol Phosphate Pathway for Isoprenoid Biosynthesis in Bacteria and Plastids. A Metabolic Milestone Achieved through Genomics1

  2002cited by this paper
• Micrografting techniques for testing long-distance signalling in Arabidopsis.

  2002cited by this paper
• Tomato tos1 mutation identifies a gene essential for osmotic tolerance and abscisic acid sensitivity.

  2002cited by this paper
• Overexpression of Arabidopsis thaliana farnesyl diphosphate synthase (FPS1S) in transgenic Arabidopsis induces a cell death/senescence-like response and reduced cytokinin levels.

  2002cited by this paper
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  2001cited by this paper
• Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.

  2001cited by this paper
• Deoxyxylulose phosphate pathway to terpenoids.

  2001cited by this paper
• A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana.

  2000influential reference
• Farnesol-induced cell death and stimulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in tobacco cv bright yellow-2 cells.

  2000cited by this paper
• Functional Cloning of an Arabidopsis thalianacDNA Encoding Cycloeucalenol Cycloisomerase*

  2000cited by this paper
• FACKEL is a sterol C-14 reductase required for organized cell division and expansion in Arabidopsis embryogenesis.

  2000influential reference
• Isoprenoid biosynthesis in plants: carbon partitioning within the cytoplasmic pathway.

  1999influential reference
• Two SNF1-related protein kinases from spinach leaf phosphorylate and inactivate 3-hydroxy-3-methylglutaryl-coenzyme A reductase, nitrate reductase, and sucrose phosphate synthase in vitro.

  1999cited by this paper
• Hydrogen peroxide is generated systemically in plant leaves by wounding and systemin via the octadecanoid pathway.

  1999cited by this paper
• Regulatory interaction of PRL1 WD protein with Arabidopsis SNF1-like protein kinases.

  1999cited by this paper
• Initiation of Runaway Cell Death in an Arabidopsis Mutant by Extracellular Superoxide

  1996cited by this paper
• Light Suppresses 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene Expression in Arabidopsis thaliana

  1996cited by this paper
• Regulation of 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Degradation by the Nonsterol Mevalonate Metabolite Farnesol in Vivo(*)

  1996cited by this paper
• Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein.

  1996cited by this paper
• The Metal-Insulator Transition in Correlated Disordered Systems

  1996cited by this paper
• The Biochemistry and Molecular Biology of Isoprenoid Metabolism

  1995cited by this paper
• Targeting and topology in the membrane of plant 3-hydroxy-3-methylglutaryl coenzyme A reductase.

  1995cited by this paper
• Bacterial expression of the catalytic domain of 3-hydroxy-3-methylglutaryl-CoA reductase (isoform HMGR1) from Arabidopsis thaliana, and its inactivation by phosphorylation at Ser577 by Brassica oleracea 3-hydroxy-3-methylglutaryl-CoA reductase kinase.

  1995cited by this paper
• The use of an alternative promoter in the Arabidopsis thaliana HMG1 gene generates an mRNA that encodes a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase isoform with an extended N-terminal region.

  1995influential reference
• Terpenoid metabolism.

  1995influential reference
• Arabidopsis thaliana contains two differentially expressed 3-hydroxy-3-methylglutaryl-CoA reductase genes, which encode microsomal forms of the enzyme.

  1994cited by this paper
• Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

  1994cited by this paper
• Exhaustive matching of the entire protein sequence database.

  1992influential reference
• Genetic analysis

  1957cited by this paper

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• Knockout of the Bread Wheat CER9/SUD1 Gene Using CRISPR/Cas Technology

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• The Arabidopsis E3 ubiquitin ligase DOA10A promotes localization of abscisic acid (ABA) receptors to the membrane through mono-ubiquitination in ABA signaling.

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• Plant terpenoid biosynthetic network and its multiple layers of regulation.

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• Membralin is required for maize development and defines a branch of the endoplasmic reticulum–associated degradation pathway in plants

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  2020cites this paper
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  2020cites this paper
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  2014influential citation
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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