Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells

Lee et al. reveal that administration of IL-1β can alter the host environment to augment the magnitude and functionality of CD8+ T cells, thereby improving the efficacy of adoptively transferred tumor-reactive T cells in treating large, established tumors in mice.

• Publication year

  2019

• Venue

  Journal of Experimental Medicine

• Publication date

  2019-08-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20181218PMID 31405895PMCID 6829590
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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