Expression and function of cell cycle proteins in rheumatoid arthritis synovial tissue.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Histology and Histopathology

• Publication date

  2006-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.14670/HH-21.205PMID 16329045
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• References Subscriptions Permissions Email Alerts Activation of the IL-4 STAT Pathway in

  2013cited by this paper
• Expression pattern of cell cycle-related gene products in synovial stroma and synovial lining in active and quiescent stages of rheumatoid arthritis.

  2005cited by this paper
• Detection of the p53 regulator murine double-minute protein 2 in rheumatoid arthritis.

  2005cited by this paper
• Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice.

  2004cited by this paper
• Pathobiology of hemophilic synovitis I: overexpression of mdm2 oncogene.

  2004cited by this paper
• Rheumatoid arthritis synovial fluid fibroblasts express TRAIL-R2 (DR5) that is functionally active.

  2004cited by this paper
• Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3.

  2003cited by this paper
• PTEN Induces Cell Cycle Arrest by Decreasing the Level and Nuclear Localization of Cyclin D1

  2003cited by this paper
• Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues.

  2003cited by this paper
• Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium

  2003cited by this paper
• TRAIL-R2 (DR5) Mediates Apoptosis of Synovial Fibroblasts in Rheumatoid Arthritis1

  2003cited by this paper
• Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL−/− mice

  2003cited by this paper
• MDM2-ARF complex regulates p53 sumoylation

  2003cited by this paper
• IL-6 and Matrix Metalloproteinase-1 Are Regulated by the Cyclin-Dependent Kinase Inhibitor p21 in Synovial Fibroblasts1

  2003cited by this paper
• Rheumatoid Arthritis Synoviocyte Survival Is Dependent on Stat31

  2002cited by this paper
• p21Cip1 Promotes Cyclin D1 Nuclear Accumulation via Direct Inhibition of Nuclear Export*

  2002cited by this paper
• A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis

  2002cited by this paper
• Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis.

  2001cited by this paper
• Preferential and persistent activation of the STAT1 pathway in rheumatoid synovial fluid cells.

  2001cited by this paper
• Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints.

  2001cited by this paper
• Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium.

  2000cited by this paper
• Adenoviral Transfer of Cyclin-Dependent Kinase Inhibitor Genes Suppresses Collagen-Induced Arthritis in Mice1

  2000cited by this paper
• Modulation of fibroblast-mediated cartilage degradation by articular chondrocytes in rheumatoid arthritis.

  2000cited by this paper
• Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Is an Inhibitor of Autoimmune Inflammation and Cell Cycle Progression

  2000cited by this paper
• Mutations in the retinoblastoma-related gene RB2/p130 in lung tumors and suppression of tumor growth in vivo by retrovirus-mediated gene transfer.

  2000cited by this paper
• The p53 status in juvenile chronic arthritis and rheumatoid arthritis

  2000cited by this paper
• MDM2--master regulator of the p53 tumor suppressor protein.

  2000cited by this paper
• Expression of sentrin, a novel antiapoptotic molecule, at sites of synovial invasion in rheumatoid arthritis.

  2000cited by this paper
• Surfing the p53 network

  2000cited by this paper
• Cell cycle arrest by the PTEN tumor suppressor is target cell specific and may require protein phosphatase activity.

  2000cited by this paper
• The Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptors TRAIL-R1 and TRAIL-R2 Have Distinct Cross-linking Requirements for Initiation of Apoptosis and Are Non-redundant in JNK Activation*

  2000cited by this paper
• C-myc antisense oligodeoxynucleotides can induce apoptosis and down-regulate Fas expression in rheumatoid synoviocytes.

  1999cited by this paper
• Activation of p53 by conjugation to the ubiquitin‐like protein SUMO‐1

  1999cited by this paper
• Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

  1999cited by this paper
• Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis.

  1999cited by this paper
• Functions of the MDM2 oncoprotein

  1999cited by this paper
• The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts

  1999cited by this paper
• RB regulates the stability and the apoptotic function of p53 via MDM2.

  1999cited by this paper
• Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction

  1999cited by this paper
• SUMO‐1 modification activates the transcriptional response of p53

  1999cited by this paper
• Altered memory T cell differentiation in patients with early rheumatoid arthritis.

  1999cited by this paper
• Expression of p21Cip1/Waf1/Sdi1 and p27Kip1Cyclin-Dependent Kinase Inhibitors During Human Hematopoiesis

  1999cited by this paper
• Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN.

  1998cited by this paper
• Mutations of the p53 tumour suppressor gene in erosive rheumatoid synovial tissue

  1998cited by this paper
• Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL*

  1998cited by this paper
• Regulation of synoviocyte proliferation, apoptosis, and invasion by the p53 tumor suppressor gene.

  1998cited by this paper
• Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

  1997cited by this paper
• Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

  1997cited by this paper
• PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

  1997cited by this paper
• Detection of p53 in inflammatory tissue and lymphocytes using immunohistology and flow cytometry: a critical comment.

  1997cited by this paper
• New functional activities for the p21 family of CDK inhibitors.

  1997cited by this paper
• Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium.

  1997cited by this paper
• Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

  1997cited by this paper
• Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.

  1996cited by this paper
• Apoptosis in rheumatoid arthritis: p53 overexpression in rheumatoid arthritis synovium.

  1996cited by this paper
• Localisation of apoptosis and expression of apoptosis related proteins in the synovium of patients with rheumatoid arthritis.

  1996cited by this paper
• Retinoblastoma gene mutations in primary human prostate cancer

  1995cited by this paper
• Interaction between the retinoblastoma protein and the oncoprotein MDM2

  1995cited by this paper
• Activation of monocyte effector genes and STAT family transcription factors by inflammatory synovial fluid is independent of interferon gamma

  1995cited by this paper
• Regulation of the balance of cytokine production and the signal transducer and activator of transcription (STAT) transcription factor activity by cytokines and inflammatory synovial fluids

  1995cited by this paper
• Synovial fibroblast-like cell transfection with the SV40 large T antigen induces a transformed phenotype and permits transient tumor formation in immunodeficient mice.

  1994cited by this paper
• p53 mutations in human cancers.

  1991cited by this paper
• Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.

  1989cited by this paper
• Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cells): correlation with rheumatoid arthritis.

  1989cited by this paper
• The major ras induced protein in NIH3T3 cells is cathepsin L.

  1987cited by this paper

• Differential DNA methylation patterns in whole blood from ACPA-positive patients with DMARD-naïve rheumatoid arthritis at clinical disease onset

  2025cites this paper
• Natural products in rheumatoid arthritis: Cell type-specific mechanisms and therapeutic implications.

  2025cites this paper
• Network analysis combined with pharmacological evaluation strategy to reveal the mechanism of Tibetan medicine Wuwei Shexiang pills in treating rheumatoid arthritis

  2022cites this paper
• PGK1, a glucose metabolism enzyme, may play an important role in rheumatoid arthritis

  2016cites this paper
• Thoracolumbar Epidural Pannus Causing Paraplegia in Rhematoid Arthritis

  2015cites this paper
• Anti-DR5 mAb inhibits proliferation of human fibroblast-like synovial cells and reduces their cytokine secretion in vitro

  2015influential citation
• Tissue factor expression in rheumatoid synovium: a potential role in pannus invasion of rheumatoid arthritis.

  2013cites this paper
• Year : 2008 Subintimal Ki-67 as a synovial tissue biomarker for inflammatory

  2008cites this paper
• Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane

  2008cites this paper
• Is steroid resistance related to multidrug resistance-I (MDR-I) in rheumatoid arthritis?

  2007cites this paper
• Subintimal Ki-67 as a synovial tissue biomarker for inflammatory arthropathies

  2007cites this paper