Regeneration of lesioned entorhino‐hippocampal axons in vitro by combined degradation of inhibitory proteoglycans and blockade of Nogo‐66/NgR signaling

No abstract is available for this paper.

• Publication year

  2006

• Venue

  The FASEB Journal

• Publication date

  2006-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1096/fj.05-5121fjePMID 16407455
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• ReportA TNF Receptor Family Member , TROY , Is a Coreceptor with Nogo Receptor in Mediating the Inhibitory Activity of Myelin Inhibitors

  2005cited by this paper
• The Nogo-66 Receptor Homolog NgR2 Is a Sialic Acid-Dependent Receptor Selective for Myelin-Associated Glycoprotein

  2005cited by this paper
• TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration.

  2005cited by this paper
• Effect of combined treatment with methylprednisolone and soluble Nogo‐66 receptor after rat spinal cord injury

  2005cited by this paper
• Overexpression of myelin-associated glycoprotein after axotomy of the perforant pathway.

  2005cited by this paper
• Chondroitin sulfate proteoglycans in neural development and regeneration.

  2005cited by this paper
• Chronic Enhancement of the Intrinsic Growth Capacity of Sensory Neurons Combined with the Degradation of Inhibitory Proteoglycans Allows Functional Regeneration of Sensory Axons through the Dorsal Root Entry Zone in the Mammalian Spinal Cord

  2005cited by this paper
• A TNF receptor family member, TROY, is a coreceptor with Nogo receptor in mediating the inhibitory activity of myelin inhibitors.

  2005cited by this paper
• A Neutralizing Anti-Nogo66 Receptor Monoclonal Antibody Reverses Inhibition of Neurite Outgrowth by Central Nervous System Myelin*

  2004cited by this paper
• Versican V2 and the central inhibitory domain of Nogo-A inhibit neurite growth via p75NTR/NgR-independent pathways that converge at RhoA.

  2004cited by this paper
• Nogo and axon regeneration.

  2004cited by this paper
• PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration

  2004cited by this paper
• The Nogo signaling pathway for regeneration block.

  2004cited by this paper
• Regeneration beyond the glial scar

  2004cited by this paper
• Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions.

  2004cited by this paper
• Promotion of Axon Regeneration by Myelin-Associated Glycoprotein and Nogo through Divergent Signals Downstream of Gi/G

  2004cited by this paper
• LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

  2004cited by this paper
• Delayed Systemic Nogo-66 Receptor Antagonist Promotes Recovery from Spinal Cord Injury

  2003cited by this paper
• Rho Kinase Inhibition Enhances Axonal Regeneration in the Injured CNS

  2003cited by this paper
• Lack of enhanced spinal regeneration in Nogo-deficient mice.

  2003cited by this paper
• Targeting the Nogo Receptor to Treat Central Nervous System Injuries

  2003cited by this paper
• Molecular analysis of Nogo expression in the hippocampus during development and following lesion and seizure 1

  2003cited by this paper
• Chondroitinase ABC promotes functional recovery after spinal cord injury

  2002cited by this paper
• Gangliosides are functional nerve cell ligands for myelin-associated glycoprotein (MAG), an inhibitor of nerve regeneration

  2002cited by this paper
• Involvement of Cajal–Retzius cells in robust and layer‐specific regeneration of the entorhino‐hippocampal pathways

  2002influential reference
• Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC

  2001cited by this paper
• Regeneration of entorhinal fibers in mouse slice cultures is age dependent and can be stimulated by NT-4, GDNF, and modulators of G-proteins and protein kinase C.

  2001cited by this paper
• Reorganization of the Rat Fascia Dentata after a Unilateral Entorhinal Cortex Lesion: Role of the Extracellular Matrix

  2000cited by this paper
• Involvement of Non‐Neuronal Cells in Entorhinal‐Hippocampal Reorganization Following Lesions

  2000cited by this paper
• Neutralizing antibodies against neurite growth inhibitor NI-35/250 do not promote regeneration of sensory axons in the adult rat spinal cord.

  2000cited by this paper
• A role for Cajal–Retzius cells and reelin in the development of hippocampal connections

  1997cited by this paper
• Lack of evidence that myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS.

  1995cited by this paper
• Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

  1994cited by this paper
• Neurite Outgrowth Inhibitors in Gliotic Tissue

  1992cited by this paper
• A double staining technique for simultaneous demonstration of astrocytes and microglia in brain sections and astroglial cell cultures.

  1991cited by this paper

• Prion and "Prion-Like" Detection: From Conventional Methods to Microfluidics or Lab-on-Chip Platforms to Monitor Seeding and Spreading of Misfolded Proteins.

  2025cites this paper
• Biomaterial and tissue-engineering strategies for the treatment of brain neurodegeneration

  2022cites this paper
• Emerging Approaches for Regenerative Rehabilitation Following Traumatic Brain Injury Regenerative Rehabilitation in TBI

  2022cites this paper
• PLGA-PEG-PLGA hydrogel with NEP1-40 promotes the functional recovery of brachial plexus root avulsion in adult rats

  2021cites this paper
• Scaffold-mediated sequential drug/gene delivery to promote nerve regeneration and remyelination following traumatic nerve injuries.

  2019cites this paper
• Advanced biomaterial strategies to transplant preformed micro-tissue engineered neural networks into the brain

  2016influential citation
• Receptors of Chondroitin Sulfate Proteoglycans and CNS Repair

  2016cites this paper
• Molecular mechanisms of scar-sourced axon growth inhibitors.

  2015cites this paper
• Restoring nervous system structure and function using tissue engineered living scaffolds

  2015cites this paper
• Rebuilding Brain Circuitry with Living Micro-Tissue Engineered Neural Networks

  2015cites this paper
• Astrogliosis and Axonal Regeneration

  2015cites this paper
• CLARIFYING THE ROLE OF MICROGLIA VERSUS MACROPHAGES IN FACILITATING NEUROINFLAMMATION SURROUNDING INTRACORTICAL MICROELECTRODES

  2014cites this paper
• Myelin-associated inhibitors in axonal growth after CNS injury.

  2014cites this paper
• BioPEGylation of polyhydroxybutyrate promotes nerve cell health and migration.

  2014cites this paper
• Combination treatment with anti‐Nogo‐A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury

  2013cites this paper
• Chondroitinase Enhances Cortical Map Plasticity and Increases Functionally Active Sprouting Axons after Brain Injury

  2013cites this paper
• Scar-mediated inhibition and CSPG receptors in the CNS.

  2012cites this paper
• The challenges of long-distance axon regeneration in the injured CNS.

  2012cites this paper
• Microtissue Engineered Constructs with Living Axons for Targeted Nervous System Reconstruction

  2012cites this paper
• An organotypic spinal cord slice culture model to quantify neurodegeneration.

  2012cites this paper
• On nogo receptors, plasticity and lasting memories

  2012cites this paper
• Neural tissue engineering for neuroregeneration and biohybridized interface microsystems in vivo (Part 2).

  2011cites this paper
• Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury

  2011influential citation
• TAT-NEP1-40 as a novel therapeutic candidate for axonal regeneration and functional recovery after stroke

  2011cites this paper
• Role of nogo - a in the intact central nervous system: an in vivo and in vitro approach.

  2011cites this paper
• Mecanismes moleculars implicats en la secreció de pèptids en cèl•lules glials del sistema nerviós central

  2011cites this paper
• The effects of combining chondroitinase ABC and NEP1-40 on the corticospinal axon growth in organotypic co-cultures.

  2010cites this paper
• The role of Interleukin-6 in nervous regeneration and functional recovery in organotypic hippocampal slice cultures

  2010cites this paper
• Regenerating cortical connections in a dish: the entorhino-hippocampal organotypic slice co-culture as tool for pharmacological screening of molecules promoting axon regeneration

  2010cites this paper
• Neurites regrowth of cortical neurons by GSK3β inhibition independently of Nogo receptor 1

  2010cites this paper
• Axonal regeneration in hippocampal and spinal cord organotypic slice cultures

  2010cites this paper
• Effect of Combined Treatment with Methylprednisolone and Nogo-A Monoclonal Antibody after Rat Spinal Cord Injury

  2010cites this paper
• Synergistic Effect of Neural Stem Cells and Olfactory Ensheathing Cells on Repair of Adult Rat Spinal Cord Injury

  2010cites this paper
• Chondroitinase ABC Enhances Pericontusion Axonal Sprouting But Does Not Confer Robust Improvements in Behavioral Recovery

  2010cites this paper
• [Axonal growth inhibition by chondroitin sulfate proteoglycans in the central nervous system].

  2009cites this paper
• Inhibición del crecimiento axonal por proteoglicanos de condroitin sulfato en el sistema nervioso central

  2009cites this paper
• Modulators of signal transduction pathways can promote axonal regeneration in entorhino-hippocampal slice cultures.

  2009cites this paper
• Olfactory Ensheathing Cells: Regeneration Following Spinal Cord Injury

  2009cites this paper
• Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3.

  2008cites this paper
• Spontaneous regeneration of intrinsic spinal cord axons in a novel spinal cord slice culture model

  2008cites this paper
• Trans-activator of Transcription-mediated Delivery of NEP1-40 Protein into Brain Has a Neuroprotective Effect against Focal Cerebral Ischemic Injury via Inhibition of Neuronal Apoptosis

  2008cites this paper
• Therapeutic time window for the application of chondroitinase ABC after spinal cord injury.

  2008cites this paper
• Nogo-A knockout mice: a systems biology approach to understand regeneration

  2008cites this paper
• Neutralization of the membrane protein Nogo‐A enhances growth and reactive sprouting in established organotypic hippocampal slice cultures

  2008cites this paper
• Overcoming chondroitin sulphate proteoglycan inhibition of axon growth in the injured brain: lessons from chondroitinase ABC.

  2007cites this paper
• Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics.

  2007cites this paper
• Función de netirna-1 y semaforinas secretables en la guía neuronal y axonal en el hipocampo y el cerebelo

  2006cites this paper
• The Nogo66 receptor pathway and CNS axon regeneration: new hopes for treating CNS injuries and neurodegeneration

  2006cites this paper
• Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions.

  2004cites this paper