Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-kappaB and C/EBP as potential targets.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Cancer Letters

• Publication date

  2009-01-08

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.canlet.2008.07.039PMID 18848748
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A JNK1/AP-1–Dependent, COX-2 Induction Is Implicated in 12-O-Tetradecanoylphorbol-13-Acetate–Induced Cell Transformation through Regulating Cell Cycle Progression

  2008cited by this paper
• Oligonol Inhibits UVB‐induced COX‐2 Expression in HR‐1 Hairless Mouse Skin—AP‐1 and C/EBP as Potential Upstream Targets †

  2008cited by this paper
• Antioxidative Effects of a New Lychee Fruit-Derived Polyphenol Mixture, Oligonol, Converted into a Low-Molecular Form in Adipocytes

  2008cited by this paper
• Inflammation: gearing the journey to cancer.

  2008cited by this paper
• Evaluation of the safety and toxicity of the oligomerized polyphenol Oligonol.

  2007cited by this paper
• Modulation of infection-induced inflammation and locomotive deficit and longevity in senescence-accelerated mice-prone (SAMP8) model by the oligomerized polyphenol Oligonol.

  2007cited by this paper
• Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-κB in mouse skin by blocking IκB kinase activity

  2006cited by this paper
• Low molecular proanthocyanidin dietary biofactor Oligonol: Its modulation of oxidative stress, bioefficacy, neuroprotection, food application and chemoprevention potentials.

  2006cited by this paper
• Biochemical, Molecular, and Genetic Mechanisms Cocoa Polyphenols Inhibit Phorbol Ester-Induced Superoxide Anion Formation in Cultured HL-60 Cells and Expression of Cyclooxygenase-2 and Activation of NF-kB and MAPKs in Mouse Skin In Vivo

  2006cited by this paper
• Comparative efficacy of oligonol, catechin and (-)-epigallocatechin 3-O-gallate in modulating the potassium bromate-induced renal toxicity in rats.

  2006cited by this paper
• Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2.

  2006cited by this paper
• Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets.

  2006cited by this paper
• Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity.

  2006cited by this paper
• New insights on the anticancer properties of dietary polyphenols

  2006cited by this paper
• [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin

  2005cited by this paper
• Signal transduction network leading to COX-2 Induction: a road map in search of cancer chemopreventives

  2005cited by this paper
• Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl) hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages.

  2005cited by this paper
• Mouse skin tumor promotion by sodium arsenate is associated with enhanced PCNA expression.

  2005cited by this paper
• Dietary cancer-chemopreventive compounds: from signaling and gene expression to pharmacological effects.

  2005cited by this paper
• Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals.

  2005cited by this paper
• Inflammation as a tumor promoter in cancer induction.

  2004cited by this paper
• Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention.

  2004cited by this paper
• Protective Effects of Oligomers of Grape Seed Polyphenols Against β‐Amyloid‐Induced Oxidative Cell Death

  2004cited by this paper
• Targeting signal transduction pathways by chemopreventive agents.

  2004cited by this paper
• Cyclooxygenases in cancer: progress and perspective.

  2004cited by this paper
• Effects of Ultraviolet B Exposure on the Expression of Proliferating Cell Nuclear Antigen in Murine Skin¶

  2004cited by this paper
• Transcriptional regulation of cyclo-oxygenase expression: three pillars of control.

  2003cited by this paper
• Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin.

  2003cited by this paper
• Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation.

  2003cited by this paper
• Cancer chemoprevention with dietary phytochemicals

  2003cited by this paper
• Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis

  2002cited by this paper
• Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

  2002cited by this paper
• Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation.

  2001cited by this paper
• CCAAT/enhancer binding protein-β is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling

  2001cited by this paper
• A polyphenolic fraction from grape seeds causes irreversible growth inhibition of breast carcinoma MDA-MB468 cells by inhibiting mitogen-activated protein kinases activation and inducing G1 arrest and differentiation.

  2000cited by this paper
• Role of Mitogen-Activated Protein Kinase Cascades in Mediating Lipopolysaccharide-Stimulated Induction of Cyclooxygenase-2 and IL-1β in RAW264 Macrophages1

  2000cited by this paper
• How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex.

  1999cited by this paper
• Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds.

  1999cited by this paper
• How NF-κB is activated: the role of the IκB kinase (IKK) complex

  1999cited by this paper
• Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances.

  1999cited by this paper
• Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent.

  1999cited by this paper
• Transcriptional Regulation of Cyclooxygenase-2 in Mouse Skin Carcinoma Cells

  1998cited by this paper
• CCAAT/enhancer-binding protein-delta (C/EBP-delta) is induced in growth-arrested mouse mammary epithelial cells.

  1997cited by this paper
• CCAAT/Enhancer-binding Protein-δ (C/EBP-δ) Is Induced in Growth-arrested Mouse Mammary Epithelial Cells*

  1997cited by this paper
• Transcriptional Regulation of Human Prostaglandin-endoperoxide Synthase-2 Gene by Lipopolysaccharide and Phorbol Ester in Vascular Endothelial Cells

  1995cited by this paper
• Polyphenols as cancer chemopreventive agents

  1995cited by this paper
• Cell lineage-specific and differentiation-dependent patterns of CCAAT/enhancer binding protein alpha expression in the gut epithelium of normal and transgenic mice.

  1993cited by this paper
• All-trans retinoic acid protects against conversion of chemically induced and ultraviolet B radiation-induced skin papillomas to carcinomas.

  1991cited by this paper
• A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro.

  1991cited by this paper
• Initiator and promoter induced specific changes in epidermal function and biological potential.

  1981cited by this paper

• Low-molecular-weight polyphenol promotes cell sensitivity to cisplatin and alleviates cancer-related muscle atrophy via NF-κB suppression in oral squamous cell carcinoma.

  2024cites this paper
• Litchi

  2022cites this paper
• Oligonol, a Low Molecular Weight Polyphenol, Enhances Apoptotic Cell Death in Ovarian Cancer Cells via Suppressing NF-κB Activation

  2019cites this paper
• Chemopreventive compounds from plant derived food and their bioactivity

  2018cites this paper
• Sodium selenite induces apoptosis via ROS‐mediated NF‐κB signaling and activation of the Bax–caspase‐9–caspase‐3 axis in 4T1 cells

  2018cites this paper
• Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways

  2017cites this paper
• Diet phytochemicals and cutaneous carcinoma chemoprevention: A review

  2017cites this paper
• Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice

  2017cites this paper
• Solanum trilobatum beneficially modulates dimethyl benz (a)anthracene induced skin carcinogenesis and erhlich Ascites cell induced solid tumor in mice

  2017cites this paper
• Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-Autophagy Pathway

  2016cites this paper
• Solanum trilobatum beneficially modulates dimethyl benz (a)anthracene induced skin carcinogenesis and erhlich Ascites cell induced solid tumor in mice

  2016cites this paper
• Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.

  2016cites this paper
• Global Liver Gene Expression Analysis on a Murine Metabolic Syndrome Model Treated by Low-molecular-weight Lychee Fruit Polyphenol (Oligonol®).

  2016cites this paper
• Oligonol, a lychee fruit-derived low-molecular form of polyphenol mixture, suppresses inflammatory cytokine production from human monocytes.

  2016cites this paper
• Screening for Identification of Personalized Food to Promote Adiponectin Secretion in Patients with Cancer.

  2016cites this paper
• The role of inflammation in skin cancer.

  2014cites this paper
• Targeting Nrf2-Keap1 signaling for chemoprevention of skin carcinogenesis with bioactive phytochemicals.

  2014cites this paper
• Inhibitory effects of Momordica grosvenori Swingle extracts on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mouse skin.

  2014cites this paper
• Evaluation of antiviral activity of Oligonol, an extract of Litchi chinensis, against betanodavirus.

  2013cites this paper
• Naturally occurring substances and their role in chemo-protective effects.

  2013cites this paper
• Oligonol Inhibits Dextran Sulfate Sodium-Induced Colitis and Colonic Adenoma Formation in Mice

  2013cites this paper
• Inotilone suppresses phorbol ester-induced inflammation and tumor promotion in mouse skin.

  2012cites this paper
• Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis.

  2012cites this paper
• Role of ROS and COX-2/iNOS inhibition in cancer chemoprevention: a review

  2012cites this paper
• Interactions of Flavonoids with Biomacromolecules

  2011cites this paper
• An Overview of Cancer Chemopreventive Potential and Safety of Proanthocyanidins

  2011cites this paper
• Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols

  2010cites this paper
• Meprin-alpha metalloproteases enhance lipopolysaccharide-stimulated production of tumour necrosis factor-alpha and interleukin-1beta in peripheral blood mononuclear cells via activation of NF-kappaB.

  2010cites this paper
• Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention.

  2010cites this paper
• Inhibition of LPS‐induced C/EBPδ by trichostatin a has a positive effect on LPS‐induced cyclooxygenase 2 expression in RAW264.7 cells

  2010cites this paper
• Screening of preliminary biological activities and in-vitro cultures Pereskia Bleo and Rennellia Elliptica

  2010cites this paper
• Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation.

  2010cites this paper
• 3,3′‐diindolylmethane suppresses 12‐O‐tetradecanoylphorbol‐13‐acetate‐induced inflammation and tumor promotion in mouse skin via the downregulation of inflammatory mediators

  2010cites this paper
• Current world literature.

  2009cites this paper
• Efeito Anti-cancerígeno do Galhato de Epigalocatequina (EGCG) em Células de Melanoma Humano

  2009cites this paper
• The Function of the Next Generation of Polyphenol “Oligonol”

  2008cites this paper