Stimulation of insulin release in isolated rat islets by GIP in physiological concentrations and its relation to islet cyclic AMP content

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Diabetologia

• Publication date

  1985-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00291078PMID 2417905
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gastric Inhibitory Polypeptide

  2020cited by this paper
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  1983cited by this paper
• Involvement of Ca2+ in the Impaired Glucose-induced Insulin Release from Islets Cultured at Low Glucose

  1983cited by this paper
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  1982influential reference
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  1979cited by this paper
• Pancreatic α- and β-cell responses to GIP infusion in normal man

  1979cited by this paper
• Release of gastric inhibitory polypeptide (GIP) by intraduodenal acidification in rats and humans and abolishment of the incretin effect of acid by GIP-antiserum in rats.

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• REGULATION OF CALCIUM FLUXES AND THEIR REGULATORY ROLES IN PANCREATIC ISLETS *

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• Glucose-dependent insulinotropic polypeptide (GIP)

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• Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk

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• GPCR's and Endocrinology

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• The Role of GIP Receptor in the CNS for the Pathogenesis of Obesity

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• Regulated expression and function of the GABAB receptor in human pancreatic beta cell line and islets

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• Experimental study on the effect of Tibetan Medicine Triphala on the Proliferation and apoptosis of Pancreatic Islet β cells through incretin/cAMP signaling Pathway.

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• Chapter 13 Cyclic AMP Signalling in Pancreatic Islets

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• Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion

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• Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

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• Glucagon-Like Peptide 1 and Gastric Inhibitory Polypeptide

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• Glucose-dependent Insulinotropic Polypeptide (GIP) Inhibits Signaling Pathways of Advanced Glycation End Products (AGEs) in Endothelial Cells via its Antioxidative Properties

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• Glucose‐dependent insulinotropic peptide impairs insulin signaling via inducing adipocyte inflammation in glucose‐dependent insulinotropic peptide receptor‐overexpressing adipocytes

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• The effect of dietary components on osteocyte mechanosensitivity: implications for bone heallth

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• GIP and Bariatric Surgery

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• Marine invertebrate and bacterial extract library screens for novel modulators of the glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors

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• The Role of Incretins in Insulin Secretion

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• Noncanonical Activation of Akt/Protein Kinase B in β-Cells by the Incretin Hormone Glucose-dependent Insulinotropic Polypeptide*

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• Glucose-dependent insulinotropic polypeptide (Gastric Inhibitory Polypeptide; GIP).

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• Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose.

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• Las incretinas como nuevas dianas terapéuticas de la diabetes tipo 2

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• Prohormone Convertase 1/3 Is Essential for Processing of the Glucose-dependent Insulinotropic Polypeptide Precursor*

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• GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice.

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• Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors.

  2004influential citation
• Studies on the potential utilization of glucose-dependent insulinotropic polypeptide (GIP) in type 1 and type 2 diabetes

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• Glucose-dependent insulinotropic polypeptide (GIP) activation of protein kinase B (PKB) and its contribution to pancreatic B-cell survival

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• GIP as a potential therapeutic agent?

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• Glucose-dependent insulinotropic peptide stimulates thymidine incorporation in endothelial cells: role of endothelin-1.

  2003cites this paper
• A New Pathway for Glucose-dependent Insulinotropic Polypeptide (GIP) Receptor Signaling

  2001cites this paper
• The entero-insular axis in type 2 diabetes--incretins as therapeutic agents.

  2001cites this paper
• Insulin secretion defects in liver cirrhosis can be reversed by glucagon-like peptide-1.

  2000cites this paper
• Comparison of the effect of native glucagon‐like peptide 1 and dipeptidyl peptidase IV‐resistant analogues on insulin release from rat pancreatic islets

  1999cites this paper
• Necessity of endogenous GTP derived from glucose-6-phosphate for insulin secretion augmented by glucose under protein kinase A activation.

  1998cites this paper
• Inhibition of glucose stimulated insulin secretion by neuropeptide Y is mediated via the Y1 receptor and inhibition of adenylyl cyclase in RIN 5AH rat insulinoma cells

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• Design of the Entero-Insular Axis

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• GIP receptors and signal-transduction mechanisms.

  1996cites this paper
• Glucose-dependent insulinotropic polypeptide stimulates insulin secretion via increased cyclic AMP and [Ca2+]1 and a wortmannin-sensitive signalling pathway.

  1996cites this paper
• Distribution of glucagon receptors on hormone-specific endocrine cells of rat pancreatic islets.

  1996cites this paper
• Gastric inhibitory polypeptide (GIP) binding sites in rat brain.

  1994cites this paper
• THE EFFECT OF DIFFERENT SOLUTIONS FOR ORGAN PRESERVATION ON IMMEDIATE POSTISCHEMIC PANCREATIC FUNCTION IN VITRO

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• Activin A: its effects on rat pancreatic islets and the mechanism of action involved.

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• Glucose-dependent insulinotropic polypeptide stimulated insulin release from a tumor-derived beta-cell line (beta TC3).

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• Binding specificity and signal transduction of receptors for glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide on RINm5F insulinoma cells.

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• Influence of glucagon-like peptide-1 on beta cell responsiveness.

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• Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations.

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• The perfused porcine pancreas as a model for testing organ protective solutions

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• Mechanism of galanin-inhibited insulin release. Occurrence of a pertussis-toxin-sensitive inhibition of adenylate cyclase.

  1988cites this paper
• Immunoreactive gastric inhibitory polypeptide.

  1988cites this paper
• The Effects of Gastric Inhibitory Polypeptide and Insulin on Fatty Acid Uptake in Adipose Tissue are not Mediated Through Cyclic AMP in Lean and Obese Zucker Rats

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• Synergistic impact of cholecystokinin and gastric inhibitory polypeptide on the regulation of insulin secretion.

  1988cites this paper
• Modulation of Insulin Secretion From β-Cells by Phosphoinositide-Derived Second-Messenger Molecules

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• Influence of cAMP and Calcium on [3H]Inositol Efflux, Inositol Phosphate Accumulation, and Insulin Release From Isolated Rat Islets

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• Adenylate cyclase in membrane fractions of RIN‐A2‐cells: Studies with forskolin, NaF, GppNHp and NEM

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• Stimulatory effects of cholecystokinin on isolated perifused islets inhibited by potent and specific antagonist L 364718 [corrected].

  1988cites this paper
• Hormone Responsiveness of Collagenase-Isolated Rat Islets is Markedly Increased by Short-Term Maintenance in Tissue Culture

  1988cites this paper
• Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes

  1988cites this paper
• Nutrient and hormonal regulation of the threshold of glucose-stimulated insulin secretion in isolated rat pancreases.

  1988cites this paper
• Effects of amino acids, hormones and drugs on insulin release and 45Ca uptake by transplantable rat insulinoma cells maintained in tissue culture.

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• Cholecystokinin (CCK8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose

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  1987cites this paper
• Evidence of Functional Gastric Inhibitory Polypeptide (GIP) Receptors in Human Insulinoma: Binding of Synthetic Human GIP 1-31 and Activation of Adenylate Cyclase

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  1986cites this paper
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