The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density

C. Termini,M. Cotter,Kristopher D. Marjon,T. Buranda,K. Lidke,J. Gillette

Published 2014 in Molecular Biology of the Cell

ABSTRACT

CD82 expression alters cell–matrix adhesion and integrin surface expression. The use of superresolution microscopy together with protein clustering algorithms leads to identification of a critical role for CD82 in regulating the molecular density of the α4 integrin.

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