The Effects of Thymopentin on the Development of SLE‐Like Syndrome in the MRL/lpr‐lpr Mouse

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Scandinavian Journal of Immunology

• Publication date

  1994-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-3083.1994.tb03503.xPMID 7973460
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Leukotrienes in renal transplant rejection in rats. Distinct roles for leukotriene B4 and peptidoleukotrienes in the pathogenesis of allograft injury.

  1994cited by this paper
• In vivo treatment with a monoclonal antibody to interferon-gamma neither affects the survival nor the incidence of lupus-nephritis in the MRL/lpr-lpr mouse.

  1992cited by this paper
• Liver of MRL/lpr mice contain interleukin‐4‐producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones

  1992cited by this paper
• Induction of IgG3 secretion by interferon gamma: a model for T cell- independent class switching in response to T cell-independent type 2 antigens

  1992cited by this paper
• Thymopentin reduces the susceptibility of aged mice to cutaneous leishmaniasis by modulating CD4 T-cell subsets.

  1992cited by this paper
• IgG3 production in MRL/lpr mice is responsible for development of lupus nephritis.

  1991cited by this paper
• Elevated production of interferon‐γ and interleukin 4 by mature T cells from autoimmune Ipr mice correlates with Pgp‐1 (CD44) expression

  1991cited by this paper
• Enhanced renal leukotriene production in murine lupus: role of lipoxygenase metabolites.

  1991cited by this paper
• Age-associated increase in interleukin 6 in MRL/lpr mice.

  1991cited by this paper
• IFN-gamma inhibits inflammatory cell recruitment and the evolution of bacterial cell wall-induced arthritis.

  1991cited by this paper
• Diethyldithiocarbamate, a novel immunomodulator, prolongs survival in autoimmune MRL-lpr/lpr mice.

  1990cited by this paper
• In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp‐lpr/lpr mouse

  1990cited by this paper
• Therapeutic effect of 15‐deoxyspergualin on the progression of lupus nephritis in MRL mice. I. Immunopathological analyses

  1990cited by this paper
• Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus

  1990cited by this paper
• Chronic thromboxane inhibition preserves function of rejecting rat renal allografts.

  1989cited by this paper
• Enhanced interferon-gamma (IFN) production by lymph node cells from autoimmune (MRL/1, MRL/n) mice.

  1989cited by this paper
• [Correction of lipid peroxidation in stress with the peptide bioregulator thymopentin].

  1989cited by this paper
• Effect of FK-506, a novel immunosuppressive drug on murine systemic lupus erythematosus.

  1989cited by this paper
• Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

  1988cited by this paper
• The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice

  1988cited by this paper
• Ly‐6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon‐gamma

  1988cited by this paper
• IL-1 induces IL-1. III. Specific inhibition of IL-1 production by IFN-gamma.

  1988cited by this paper
• In vivo immunopotentiating activity of thymopentin in aging humans: modulation of IL-2 receptor expression.

  1988cited by this paper
• In vivo immunopotentiating activity of thymopentin in aging humans: increase of IL-2 production.

  1987cited by this paper
• In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon

  1987cited by this paper
• In vitro effects of thymopentin on the gamma-interferon production by peripheral blood mononuclear cells from normal subjects and from patients with rheumatoid arthritis.

  1987cited by this paper
• Regulation by interferons of the local inflammatory response to bacterial lipopolysaccharide.

  1987cited by this paper
• CS-A therapy in MRL-lpr/lpr mice: amelioration of immunopathology despite autoantibody production.

  1987cited by this paper
• Immunosuppressive activities of deoxyspergualin. I. Effect of the long-term administration of the drug on the development of murine lupus.

  1987cited by this paper
• Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

  1986cited by this paper
• IL-2 normalizes defective suppressor T cell function of patients with systemic lupus erythematosus in vitro.

  1986cited by this paper
• Treatment of active rheumatoid arthritis with slow intravenous injections of thymopentin. A double-blind placebo-controlled randomised study.

  1985cited by this paper
• Murine models of systemic lupus erythematosus.

  1985cited by this paper
• Cooperativity of thymopoietin 32-36 (the active site) and thymopoietin 38-45 in receptor binding.

  1984cited by this paper
• Induction and augmentation of mitogen-induced immune interferon production in human lymphocytes by a synthetic thymopoietin pentapeptide.

  1984cited by this paper
• Contrasting effects of thymopentin and splenopentin on the capacity of female mice to reject syngeneic male skin.

  1984cited by this paper
• Cyclophosphamide-induced changes in the MRL-lpr/lpr mouse: effects upon cellular composition, immune function, and disease.

  1984cited by this paper
• Interleukin 2: the molecule and its function.

  1984cited by this paper
• Phase variation in the modulation of the human immune response.

  1983cited by this paper
• Studies of thymopoietin pentapeptide (TP5) on experimental tumors. I. TP5 relieves immunosuppression in tumor-bearing mice.

  1982cited by this paper
• Abnormalities induced by the mutant gene Ipr: expansion of a unique lymphocyte subset.

  1982cited by this paper
• Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2

  1981cited by this paper
• Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene

  1981cited by this paper
• Effect of thymopoietin pentapeptide (TP5) on autoimmunity. I. TP5 suppression of induced erythrocyte autoantibodies in C3H mice.

  1980cited by this paper
• Immunological circuits: cellular composition.

  1979cited by this paper
• A synthetic pentapeptide with biological activity characteristic of the thymic hormone thymopoietin.

  1979cited by this paper
• The effect of thymopoietin32-36 and ubiquitin on spontaneous immunopathology of New Zealand mice.

  1979cited by this paper
• The generation and regulation of lymphocyte populations: evidence from differentiative induction systems in vitro

  1978cited by this paper
• Immunological studies of aging. IV. The contribution of thymic involution to the immune deficiencies of aging mice and reversal with thymopoietin32-36

  1978cited by this paper
• ANTIGENIC AND FUNCTIONAL EVIDENCE FOR THE IN VITRO INDUCTIVE ACTIVITY OF THYMOPOIETIN (THYMIN) ON THYMOCYTE PRECURSORS *

  1975cited by this paper
• THE ROLE OF VASOCONSTRICTION IN THE ISCHEMIA OF RENAL ALLOGRAFT REJECTION

  1968cited by this paper

• Therapeutic peptides for the treatment of systemic lupus erythematosus: a place in therapy

  2020cites this paper
• Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.

  2009cites this paper
• Growth factors, cytokines, chemokines and neuropeptides in the modeling of T-cells.

  2002cites this paper
• The mechanism by which a peptide based on complementarity-determining region-1 of a pathogenic anti-DNA auto-Ab ameliorates experimental systemic lupus erythematosus.

  2001cites this paper
• Dichotomic effects of IFN‐γ on the development of systemic lupus erythematosus‐like syndrome in MRL‐lpr / lpr mice

  2000influential citation
• Thymopentin and splenopentin as immunomodulators

  1998cites this paper
• Prevention of endotoxin‐induced lethality in neonatal mice by interleukin‐13

  1997cites this paper
• Cytokine production in response to stimulation with tetanus toxoid, Mycobacterium tuberculosis and influenza antigens in peripheral blood mononuclear cells and T cell lines from healthy elderlies.

  1997cites this paper
• The effects of a nonimmunogenic form of murine soluble interferon-gamma receptor on the development of autoimmune diabetes in the NOD mouse.

  1996cites this paper