Triterpenoid saponins from stem bark of Pentaclethra macroloba

Two new and two known triterpenoid saponins were isolated from the stem bark of Pentaclethra macroloba. Their structures were determined using a combination of homo- (1D 1H NMR, 13C NMR-HBBD and 13C NMR-DEPT) and heteronuclear 2D NMR techniques (1H-1H-COSY, 1H-1H-TOCSY, 1H-1H-NOESY, HMQC and HMBC), ESIMS and chemical methods. The structures of the two new pentacyclic triterpenoid saponins were established as 3b-O-{[b-D-glucopyranosyl-(1®3)-a-L-rhamnopyranosyl-(1®2)],b-D- glucopyranosyl-(1®4)}-a-L-arabinopyranosylhederagenin (3) and 3b-O-{[b-D-glucopyranosyl-(1®4)-b-D-glucopyranosyl-(1®3)-a-L-rhamnopyranosyl- (1®2)],b-D- glucopyranosyl(1®4)}-a-L-arabinopyranosyloleanolic acid (4).

• Publication year

  2004

• Venue

  Journal of the Brazilian Chemical Society

• Publication date

  2004-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1590/S0103-50532004000400024
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Phytochemical Dictionary of the Leguminosae

  1994cited by this paper
• The Leguminosae: A Source Book of Characteristics, Uses and Nodulation

  1981influential reference
• Dicionário das plantas úteis do Brasil

  1979influential reference

• Design and evaluation of nanostructured lipid carrier of Bergenin isolated from Pentaclethra macrophylla for anti-inflammatory effect on lipopolysaccharide-induced inflammatory responses in macrophages.

  2024cites this paper
• Anti-Inflammatory and Antinociceptive Activity of Herbal Lipospheres of Pentaclethra macrophylla (Fabaceae) Stem Bark Extract

  2023cites this paper
• Pentaclethra macroloba: A Review of the Biological, Pharmacological, Phytochemical, Cosmetic, Nutritional and Biofuel Potential of this Amazonian Plant

  2023cites this paper
• A Comprehensive Study on the Chemical Characterization and Neuroprotective Evaluation of Pracaxi Nuts Extracts Obtained by a Sustainable Approach

  2023influential citation
• Insight into the antioxidant activities of ten Fabaceae plant species that are medicinally used by the Aucan Tribal Peoples from the Republic of Suriname (South America)

  2022cites this paper
• Triterpenoids from Agathis robusta Aerial Parts and Their Hepatopotective Activity

  2022cites this paper
• Triterpenoid Saponins From the Stem Bark of Pentaclethra eetveldeana

  2019cites this paper
• Manosrin A New Hypoglycaemic Compound From Anisopus

  2018cites this paper
• New triterpenoidal saponins from Koelreuteria paniculata.

  2016influential citation
• Phytochemical diversity and synergistic effects on herbivores

  2016cites this paper
• A NOVEL PENTACYCLIC TRITERPENOID ISOLATED FROM CARALLUMA ATTENUATA ROOT

  2016cites this paper
• Pentaclethra macroloba tannins fractions active against methicillin-resistant staphylococcal and Gram-negative strains showing selective toxicity

  2011cites this paper
• Isolation and structure determination of acetylated triterpenoid saponins from the seeds of Centratherum anthelminticum

  2010cites this paper
• Naturally Occurring Triterpenoid Saponins

  2010cites this paper
• Facile synthesis and cytotoxicity of triterpenoid saponins bearing a unique disaccharide moiety: hederacolchiside A1 and its analogues.

  2008cites this paper
• Coumestoside A, Coumestoside B and Erythrodiside A, Three Glycosides from Cylicodiscus gabunensis (Mimmosaceae)

  2007cites this paper
• Avaliação da atividade larvicida de saponinas triterpênicas isoladas de Pentaclethra macroloba (Willd.) Kuntze (Fabaceae) e Cordia piauhiensis Fresen (Boraginaceae) sobre Aedes aegypti

  2005cites this paper