Computational models and fundamental constraints can inform the design of synthetic connectomes: Comment on "What would a synthetic connectome look like?" by Ithai Rabinowitch.

Abstract Rabinowitch's article [1] offers an outline of synthetic connectomics where, in analogy to synthetic biology, connectomes are constructed. Rather than building connectomes in a computer model, say by observing artificial neural networks, the idea is to build in vivo biological connectomes. By building connectomes from scratch this proposal is different from approaches that aim to modify already existing connectomes found in animals or humans. However, there are constraints, technical limitations, and competing approaches that will need to be considered when building connectomes.

• Publication year

  2020

• Venue

  Physics of Life Reviews

• Publication date

  2020-07-01

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1016/j.plrev.2019.08.003PMID 31416703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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