Structure of a polysaccharide from Trichoderma atroviride and its promotion on tanshinones production in Salvia miltiorrhiza hairy roots.

This study evaluates the chemical structure of a heteropolysaccharide (PSF-W-1) from the endophytic fungus Trichoderma atroviride and its effects on the production of tanshinones in Salvia miltiorrhiza hairy roots. The total carbohydrate content of isolated PSF-W-1 was determined to be 97.72%. PSF-W-1 has a relative molecular weight of 36.13 kDa and contains mannose, glucose and galactose in molar ratios of 1.00:4.86:2.25. Through methylation analysis, IR and NMR, PSF-W-1 was determined to possess a backbone of →4)-β-D-Glcp-(1→6)-α-D-Galp-(1→4)-β-D-Manp-(1→6)-α-D-Galp-(1→ with two side chains β-D-Glcp-(1→4)-β-D-Glcp-(1→ attached to O3 of 1,6-α-D-Galp. Bioactivity tests suggested that PSF-W-1 was responsible for boosting the S. miltiorrhiza hairy root growth and the biosynthesis of dihydrotanshinone I, tanshinone I, tanshinone IIA and cryptotanshinone in hairy roots. According to this study, PSF-W-1 might be utilized as a potent stimulator of tanshinones synthesis.

• Publication year

  2019

• Venue

  Carbohydrate Polymers

• Publication date

  2019-11-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.carbpol.2019.115125PMID 31426969
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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