The C-Type Lectin Receptor MCL Mediates Vaccine-Induced Immunity against Infection with Blastomyces dermatitidis

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Infection and Immunity

• Publication date

  2015-12-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.01263-15PMID 26667836PMCID PMC4771354
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice.

  2016influential reference
• Adaptive immunity to fungi.

  2015cited by this paper
• C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation

  2015cited by this paper
• The C-Type Lectin Receptor CLECSF8/CLEC4D Is a Key Component of Anti-Mycobacterial Immunity

  2015cited by this paper
• Fonsecaea pedrosoi‐induced Th17‐cell differentiation in mice is fostered by Dectin‐2 and suppressed by Mincle recognition

  2015cited by this paper
• Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes.

  2015cited by this paper
• C-Type Lectin Receptors Differentially Induce Th17 Cells and Vaccine Immunity to the Endemic Mycosis of North America

  2014influential reference
• C-type Lectin Receptor Dectin-3 Mediates Trehalose 6,6′-Dimycolate (TDM)-induced Mincle Expression through CARD9/Bcl10/MALT1-dependent Nuclear Factor (NF)-κB Activation*

  2014cited by this paper
• Signalling C‐Type lectin receptors, microbial recognition and immunity

  2014cited by this paper
• C‐type lectin receptor Clec4d plays a protective role in resolution of Gram‐negative pneumonia

  2013cited by this paper
• Structural analysis for glycolipid recognition by the C-type lectins Mincle and MCL

  2013cited by this paper
• C-type lectin receptors orchestrate antifungal immunity.

  2013cited by this paper
• Signaling while eating: MCL is coupled with Mincle

  2013cited by this paper
• The Dectin-2 family of C-type lectin-like receptors: an update

  2013cited by this paper
• Mincle, the receptor for mycobacterial cord factor, forms a functional receptor complex with MCL and FcεRI‐γ

  2013cited by this paper
• C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection.

  2013cited by this paper
• C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor.

  2013cited by this paper
• The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase

  2012cited by this paper
• C-type lectin receptors orchestrate antifungal immunity

  2012cited by this paper
• Fungi subvert vaccine T cell priming at the respiratory mucosa by preventing chemokine-induced influx of inflammatory monocytes.

  2012cited by this paper
• C-type lectin receptors and cytokines in fungal immunity.

  2012cited by this paper
• NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus, is safe and immunogenic in healthy adults.

  2012cited by this paper
• Vaccine-induced protection against 3 systemic mycoses endemic to North America requires Th17 cells in mice.

  2011cited by this paper
• Immunity to fungal infections

  2011cited by this paper
• A TCR Transgenic Mouse Reactive with Multiple Systemic Dimorphic Fungi

  2011cited by this paper
• Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.

  2010cited by this paper
• Th1-Th17 Cells Mediate Protective Adaptive Immunity against Staphylococcus aureus and Candida albicans Infection in Mice

  2009cited by this paper
• The carbohydrate-recognition domain of Dectin-2 is a C-type lectin with specificity for high mannose.

  2006cited by this paper
• Biostatistics: a Methodology for the Health Sciences

  2005cited by this paper
• Immunity to fungal infections

  2004cited by this paper
• The human C‐type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor

  2004cited by this paper
• Requisite Elements in Vaccine Immunity to Blastomyces dermatitidis: Plasticity Uncovers Vaccine Potential in Immune-Deficient Hosts1 2

  2002cited by this paper
• Mutation of the WI-1 gene yields an attenuated blastomyces dermatitidis strain that induces host resistance.

  2000cited by this paper
• Targeted Gene Disruption Reveals an Adhesin Indispensable for Pathogenicity of Blastomyces dermatitidis

  1999cited by this paper
• Cloning of a Novel C-type Lectin Expressed by Murine Macrophages*

  1998cited by this paper

• Histiocytes: Multifaceted Regulators of Health and Disease.

  2025cites this paper
• Fungal vaccines and adjuvants: a tool to reveal the interaction between host and fungi

  2024cites this paper
• The Road Ahead: Advancing Antifungal Vaccines and Addressing Fungal Infections in the Post-COVID World.

  2024cites this paper
• Diagnosis of Human Endemic Mycoses Caused by Thermally Dimorphic Fungi: From Classical to Molecular Methods

  2024cites this paper
• C-type lectin Mincle initiates IL-17-mediated inflammation in acute exacerbations of idiopathic pulmonary fibrosis.

  2023cites this paper
• Ovine C-type lectin receptor hFc-fusion protein library - A novel platform to screen for host-pathogen interactions.

  2020cites this paper
• Innate Immune Receptors and Defense Against Primary Pathogenic Fungi

  2020cites this paper
• Blastomyces and Blastomycosis

  2020cites this paper
• The Role of the Interleukin-17 Axis and Neutrophils in the Pathogenesis of Endemic and Systemic Mycoses

  2020cites this paper
• C-Type Lectin Receptor CD23 Is Required for Host Defense against Candida albicans and Aspergillus fumigatus Infection

  2018cites this paper
• Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity

  2018cites this paper
• Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

  2018cites this paper
• Antifungal Innate Immunity: A Perspective from the Last 10 Years

  2018cites this paper
• Dectin-3 Recognizes Glucuronoxylomannan of Cryptococcus neoformans Serotype AD and Cryptococcus gattii Serotype B to Initiate Host Defense Against Cryptococcosis

  2018cites this paper
• Dectin-3 recognizes cryptococcal glucuronoxylomannan to initiate host defense against cryptococcosis

  2018cites this paper
• Immunological mechanisms regulating neuroinflammation : a role for C-type lectin receptors and vitamin D

  2018cites this paper
• Immunity against fungi.

  2017cites this paper
• C-type lectin receptors in anti-fungal immunity.

  2017cites this paper
• Contact, Collaboration, and Conflict: Signal Integration of Syk-Coupled C-Type Lectin Receptors

  2017cites this paper
• The Major Chromoblastomycosis Etiologic Agent Fonsecaea pedrosoi Activates the NLRP3 Inflammasome

  2017cites this paper
• Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection

  2017cites this paper
• Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

  2017cites this paper
• Evidence of delayed dissemination or re-infection with Blastomyces in two immunocompetent hosts

  2016cites this paper