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In-vivo biological effect of Carica papaya leaf extracts on P-407 induced hyperlipidemic Wistar rats

V. D. Sheneni,Isaac Eleojo Shaibu,J. Okpe,Adams Akogwu Omada

Published 2018 in MOJ Food Processing & Technology

ABSTRACT

Tropical America is the home of Papaya, which was spread to the south by the Indians, and to the caribbean by the Spanish. Caricaceae is the family Carica papaya Linnaeus, (paw paw), belongs to, and it is an herbaceous perennial plant with rapid proliferation rate.1 Papaya has a short life span, but has a fruitage period of 20 years. Papaya has a complex type of reproduction as they are hermaphrodite i.e. with both male and female part.2 The male trees are rare, but can be obtained when homeowners collect their own seeds. The commercially available papayas are the hermaphrodite trees that produce fruits that are pear shaped. These plants are selffertilizing.3 The plant yields natural substance (Annonaceous acetogenins) in leaf barks and tissues of twig that has potent antitumor and pesticidal activities.4 Papayas are rich in self-defense compounds that confer a high level of immunity to attack by insects and to diseases.5

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