Tamoxifen induces masculinization of genetic females and regulates P450 aromatase and müllerian inhibiting substance mRNA expression in Japanese flounder (Paralichthys olivaceus)

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Molecular Reproduction and Development

• Publication date

  2007-09-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/mrd.20603PMID 17595016
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Assessment of estrogenic chemicals using an estrogen receptor α (ERα)- and ERβ-mediated reporter gene assay in fish

  2006influential reference
• Sexually dimorphic expression of a teleost homologue of Müllerian inhibiting substance during gonadal sex differentiation in Japanese flounder, Paralichthys olivaceus.

  2004influential reference
• Estrogen signaling: a subtle balance between ER alpha and ER beta.

  2003cited by this paper
• Molecular Characterization of Three Estrogen Receptor Forms in Zebrafish: Binding Characteristics, Transactivation Properties, and Tissue Distributions1

  2002cited by this paper
• Aromatase plays a key role during normal and temperature‐induced sex differentiation of tilapia Oreochromis niloticus

  2001cited by this paper
• Phylogenetic sequence analysis, recombinant expression, and tissue distribution of a channel catfish estrogen receptor beta.

  2000influential reference
• Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts.

  2000cited by this paper
• Aromatase inhibitor and 17α‐methyltestosterone cause sex‐reversal from genetical females to phenotypic males and suppression of P450 aromatase gene expression in Japanese flounder (Paralichthys olivaceus)

  2000influential reference
• Two estrogen receptors expressed in the teleost fish, Sparus aurata: cDNA cloning, characterization and tissue distribution.

  2000cited by this paper
• Sex differentiation and mRNA expression of p450c17, p450arom and AMH in gonads of the chicken

  2000cited by this paper
• Cloning, in vitro expression, and novel phylogenetic classification of a channel catfish estrogen receptor.

  1999influential reference
• Suppression of P450 aromatase gene expression in sex-reversed males produced by rearing genetically female larvae at a high water temperature during a period of sex differentiation in the Japanese flounder (Paralichthys olivaceus).

  1999influential reference
• Involvement of estrogens in the process of sex differentiation in two fish species: The rainbow trout (Oncorhynchus mykiss) and a tilapia (Oreochromis niloticus)

  1999influential reference
• Postnatal Sex Reversal of the Ovaries in Mice Lacking Estrogen Receptors α and β

  1999cited by this paper
• Temperature‐dependent sex determination in the american alligator: AMH precedes SOX9 expression

  1999cited by this paper
• Sex reversal by aromatase inhibitor treatment in the newt Pleurodeles waltl.

  1999cited by this paper
• Molecular Cloning of Estrogen Receptors α and β in the Ovary of A Teleost Fish, the Tilapia (Oreochromis niloticus)

  1999cited by this paper
• Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta.

  1999cited by this paper
• Sites of estrogen receptor and aromatase expression in the chicken embryo.

  1997influential reference
• Temperature-dependent aromatase expression in developing diamondback terrapin (Malaclemys terrapin) embryos.

  1997cited by this paper
• ERβ: Identification and characterization of a novel human estrogen receptor

  1996cited by this paper
• Cloning of a novel receptor expressed in rat prostate and ovary.

  1996cited by this paper
• ER beta: identification and characterization of a novel human estrogen receptor.

  1996cited by this paper
• Effects of aromatase inhibitor on sex differentiation and levels of P450 (17 alpha) and P450 arom messenger ribonucleic acid of gonads in chicken embryos.

  1996cited by this paper
• Putative aromatase inhibitor induces male sex determination in a female unisexual lizard and in a turtle with temperature-dependent sex determination.

  1994cited by this paper
• Masculinization of gonads by aromatase inhibitors in a turtle with temperature-dependent sex determination

  1994cited by this paper
• Brief treatment with an aromatase inhibitor during sex differentiation causes chromosomally female salmon to develop as normal, functional males

  1994cited by this paper
• Aromatase enzyme activity and sex determination in chickens.

  1992cited by this paper
• Studies on the gynogenesis in hirame Paralichthys olivaceus. XI. Induction of Gynogenetic Diploid Males and Presumption of Sex Determination Mechanisms in the Hirame Paralichthys olivaceus.

  1991cited by this paper
• Involvement of oestrogens in sexual differentiation of gonads as a function of temperature in turtles

  1991cited by this paper
• Effect of tamoxifen on H-Y antigen expression and gonadal development in chicken embryos.

  1985cited by this paper
• Tamoxifen is a potent ‘pure’ anti-oestrogen in chick oviduct

  1977cited by this paper
• Cloning of a novel estrogen receptor expressed in rat prostate and ovary

  year unknowncited by this paper

• Role of a non-steroidal aromatase inhibitor on growth performance, body composition, reproductive and serum biochemical indices, and intestinal histomorphology in hybrid red tilapia (Oreochromis spp.)

  2025cites this paper
• Beyond the Binary: Controlling Natural Sex‐Change in Hermaphroditic Fishes

  2025cites this paper
• The effects of a non-steroid aromatase inhibitor on hybrid red tilapia masculinization, growth, reproductive hormone profile, and economic efficiency in aquaculture

  2025influential citation
• Gene expression, gonadal morphology, and steroid hormone profiles during induced sex-change in the protandric hermaphrodite Centropomus undecimalis

  2025cites this paper
• Levonorgestrel-induced anal fin masculinization in mosquitofish: Do TGF-β/BMP signaling and osteogenic remodeling underpin endocrine disruption in aquatic ecosystem?

  2025cites this paper
• circRNA Profiling Reveals Regulatory Networks Underlying Gonadal Differentiation in Nile Tilapia (Oreochromis niloticus)

  2025cites this paper
• RETRACTED ARTICLE: Sexual maturation inhibition using exemestane and tamoxifen in female olive flounder (Paralichthys olivaceous)

  2024cites this paper
• Amh/Amhr2 Signaling Causes Masculinization by Inhibiting Estrogen Synthesis during Gonadal Sex Differentiation in Japanese Flounder (Paralichthys olivaceus)

  2023cites this paper
• Tilapia, a good model for studying reproductive endocrinology.

  2023cites this paper
• Testicular development and spermatogenesis in fish: insights into molecular aspects and regulation of gene expression by different exogenous factors

  2021cites this paper
• Sex Determination and Differentiation in Teleost: Roles of Genetics, Environment, and Brain

  2021cites this paper
• Anti-masculinization induced by aromatase inhibitors in adult female zebrafish

  2020cites this paper
• Dietary 17 β‐oestradiol and 17 α‐ethinyloestradiol alter gonadal morphology and gene expression of the two sex‐related genes, dmrt1 and cyp19a1a , in juvenile barramundi ( Lates calcarifer Bloch)

  2020cites this paper
• Sex reversal and ontogeny under climate change and chemical pollution: are there interactions between the effects of elevated temperature and a xenoestrogen on early development in agile frogs?

  2020cites this paper
• The Administration of Cortisol Induces Female-to-Male Sex Change in the Protogynous Orange-Spotted Grouper, Epinephelus coioides

  2020cites this paper
• Overexpression of Anti-müllerian Hormone Gene in vivo Affects Gonad Sex Differentiation in Undifferentiated Orange-Spotted Groupers (Epinephelus coioides)

  2019cites this paper
• Sex biased expression of anti-Mullerian hormone (amh) gene in a live bearing fish, Gambusia holbrooki: Evolutionary implications and potential role in sex differentiation.

  2019cites this paper
• Conservation and diversity in expression of candidate genes regulating socially-induced female-male sex change in wrasses

  2019cites this paper
• Gonad formation and pre-meiotic proliferation of gonocytes in the Japanese willow minnow Gnathopogon caerulescens

  2019cites this paper
• Tamoxifen affects the histology and hepatopancreatic lipid metabolism of swimming crab Portunus trituberculatus.

  2019cites this paper
• Expression profiles of amh and foxl2 in Schizothorax kozlovi, and their response to temperature during the early developmental stage

  2018cites this paper
• Xenobiotic metabolism in the fish hepatic cell lines Hepa-E1 and RTH-149, and the gill cell lines RTgill-W1 and G1B: Biomarkers of CYP450 activity and oxidative stress.

  2018cites this paper
• Endocrine and Environmental Control of Sex Differentiation in Gonochoristic Fish

  2018cites this paper
• Female-to-male sex reversal in orange-spotted grouper (Epinephelus coioides) caused by overexpressing of Amh in vivo†

  2018cites this paper
• Expression profiles of amh and foxl2 in Schizothorax kozlovi, and their response to temperature during the early developmental stage

  2018cites this paper
• Functional characterization of Cyp19a1 in female sexual differentiation in Pelodiscus sinensis

  2017cites this paper
• Stress and sex: does cortisol mediate sex change in fish?

  2017cites this paper
• Transcriptional and morphological effects of tamoxifen on the early development of zebrafish (Danio rerio)

  2016influential citation
• Effects of 17α-ethinylestradiol at different water temperatures on zebrafish sex differentiation and gonad development.

  2016cites this paper
• Knockout of Zebrafish Ovarian Aromatase Gene (cyp19a1a) by TALEN and CRISPR/Cas9 Leads to All-male Offspring Due to Failed Ovarian Differentiation

  2016cites this paper
• Tamoxifen disrupts the reproductive process in gilthead seabream males and modulates the effects promoted by 17α-ethynylestradiol.

  2016cites this paper
• Approaches for predicting effects of unintended environmental exposure to an endocrine active pharmaceutical, tamoxifen

  2016influential citation
• The role of Amh signaling in teleost fish--Multiple functions not restricted to the gonads.

  2015influential citation
• A review of the effects of azole compounds in fish and their possible involvement in masculinization of wild fish populations

  2015cites this paper
• The effects of temperature on cyp19a1a, foxl2, dmrt1 and amh expression during sex differentiation in summer flounder (Paralichthys dentatus)

  2015cites this paper
• organisms risks of human and veterinary pharmaceuticals to aquatic Leveraging existing data for prioritization of the ecological

  2014cites this paper
• Avaliação da eficiência do citrato de tamoxifeno na inversão sexual de tilápia do Nilo (Oreochromis niloticus) Evaluation of tamoxifen citrate efficiency on sexual inversion of Nile tilapia (Oreochromis niloticus)

  2014cites this paper
• Analyse comparative, physiologique et moléculaire des effets de trois traitements masculinisants chez le tilapia du Nil, Oreochromis niloticus, et recherche de marqueurs de traçabilité liés à ces approches

  2014influential citation
• Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms

  2014cites this paper
• A CYP19 Based Sex Determination and Monosex Production in Aquaculture Species Oreochromis niloticus L. and a Cyprinid Cyprinus carpio L.

  2014cites this paper
• Temperature induced-masculinisation in the Nile tilapia causes rapid up-regulation of both dmrt1 and amh expressions.

  2013cites this paper
• Sex steroid changes during temperature‐induced gonadal differentiation in Paralichthys olivaceus (Temminck & Schegel, 1846)

  2013cites this paper
• Divergent and sex‐dimorphic expression of the paralogs of the Sox9‐Amh‐Cyp19a1 regulatory cascade in developing and adult atlantic cod (Gadus morhua L.)

  2013cites this paper
• Creating females? Developmental effects of 17α-ethynylestradiol on the mangrove rivulus' ovotestis.

  2012cites this paper
• ROLE OF THYROID HORMONES IN THE DEVELOPMENT OF GONADAL SEX, EXTERNAL MORPHOLOGY AND INTESTINAL SYSTEM OF ZEBRAFISH (DANIO RERIO)

  2012cites this paper
• Mating behavior as non-invasive biomarker in Xenopus laevis for the assessment of endocrine disrupting compounds

  2012influential citation
• Caractérisation du phénotype associé à la mutation masculinisante "mal" chez la truite arc-enciel, Oncorhynchus mykiss

  2012cites this paper
• Estrogen rescues masculinization of genetically female medaka by exposure to cortisol or high temperature

  2012cites this paper
• Effects of methyltestosterone, tamoxifen, genistein and Basella alba extract on masculinization of guppy (Poecilia reticulata)

  2012cites this paper
• High temperature induces cyp26b1 mRNA expression and delays meiotic initiation of germ cells by increasing cortisol levels during gonadal sex differentiation in Japanese flounder.

  2012cites this paper
• Molecular characterization of estrogen receptor genes in Gobiocypris rarus and their expression upon endocrine disrupting chemicals exposure in juveniles.

  2011cites this paper
• Bisphenol A modulates expression of sex differentiation genes in the self-fertilizing fish, Kryptolebias marmoratus.

  2011cites this paper
• Transcriptional responses in the brain, liver and gonad of Japanese ricefish (Oryzias latipes) exposed to two anti-estrogens.

  2011influential citation
• Molecular cloning, characterization and expression profiles of three estrogen receptors in protogynous hermaphroditic orange-spotted grouper (Epinephelus coioides).

  2011cites this paper
• Studies on feminization, sex determination, and differentiation of the Southern catfish, Silurus meridionalis—a review

  2010cites this paper
• Cortisol is involved in temperature-dependent sex determination in the Japanese flounder.

  2010cites this paper
• Ovarian aromatase and estrogens: a pivotal role for gonadal sex differentiation and sex change in fish.

  2010cites this paper
• Sexual determination and differentiation in teleost fish

  2010cites this paper
• Morphological sex change upon treatment by endocrine modulators in meiogynogenetic tench (Tinca tinca L.)

  2010cites this paper
• Elevated amh Gene Expression in the Brain of Male Tilapia (Oreochromis niloticus) during Testis Differentiation

  2010influential citation
• III - 3. Sex-manipulation by control of environmental factors

  2009cites this paper
• Masculinization of the European sea bass (Dicentrarchus labrax) by treatment with an androgen or aromatase inhibitor involves different gene expression and has distinct lasting effects on maturation.

  2009cites this paper
• Effects of cypermethrin chronic exposure and water temperature on survival, growth, sex differentiation, and gonadal developmental stages of Odontesthes bonariensis (Teleostei).

  2009influential citation
• Fish Gonadogenesis. Part II: Molecular Biology and Genomics of Sex Differentiation

  2008cites this paper
• Follicle-stimulating hormone signaling and Foxl2 are involved in transcriptional regulation of aromatase gene during gonadal sex differentiation in Japanese flounder, Paralichthys olivaceus.

  2007cites this paper
• Inhibition of sexual maturation inhibition using exemestane and tamoxifen in female olive �ounder (Paralichthys olivaceous)

  year unknowncites this paper