Exploring oxidovanadium(iv) homoleptic complexes with 8-hydroxyquinoline derivatives as prospective antitrypanosomal agents

Gonzalo Scalese,I. Machado,I. Correia,J. Pessoa,L. Bilbao,Leticia Pérez‐Díaz,D. Gambino

Published 2019 in New Journal of Chemistry

ABSTRACT

[VIVO(L-H)2] and [VVO(OCH3)(L-H)2] compounds of 8-hydroxyquinoline derivatives L showed activity againstTrypanosoma cruziandLeishmania infantumand high selectivities. Metallomics and interaction with BSA, apo-HTF and DNA were studied.

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