Synthesis, screening and biological activity of potent thiosemicarbazone compounds as a tyrosinase inhibitor

Penggen Cai,Yi Xiong,Yao Yao,Wu Chen,Xiongwei Dong

Published 2019 in New Journal of Chemistry

ABSTRACT

Inhibitors are designed based on coordination chemistry and catalytic circle of the tyrosinase, coordination atoms binds to copper and blocks enzyme activity, indicated that thiosemicarbazone species possess good potential as tyrosinase inhibitors.

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