Inhibitors are designed based on coordination chemistry and catalytic circle of the tyrosinase, coordination atoms binds to copper and blocks enzyme activity, indicated that thiosemicarbazone species possess good potential as tyrosinase inhibitors.
Synthesis, screening and biological activity of potent thiosemicarbazone compounds as a tyrosinase inhibitor
Penggen Cai,Yi Xiong,Yao Yao,Wu Chen,Xiongwei Dong
Published 2019 in New Journal of Chemistry
ABSTRACT
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- Publication year
2019
- Venue
New Journal of Chemistry
- Publication date
2019-09-09
- Fields of study
Medicine, Chemistry
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Semantic Scholar
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