Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Pulmonary Pharmacology & Therapeutics

• Publication date

  2006-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.PUPT.2005.08.002PMID 16203165
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries.

  2003cited by this paper
• Inhibitors of pentose phosphate pathway cause vasodilation: involvement of voltage-gated potassium channels.

  2002cited by this paper
• Diversity in Mitochondrial Function Explains Differences in Vascular Oxygen Sensing

  2002cited by this paper
• Redox signaling in oxygen sensing by vessels.

  2002cited by this paper
• Graded response of K+ current, membrane potential, and [Ca2+]i to hypoxia in pulmonary arterial smooth muscle.

  2002cited by this paper
• Epiandrosterone, a metabolite of testosterone precursor, blocks L-type calcium channels of ventricular myocytes and inhibits myocardial contractility.

  2002cited by this paper
• Hypoxic pulmonary vasoconstriction: cyclic adenosine diphosphate-ribose, smooth muscle Ca(2+) stores and the endothelium.

  2002cited by this paper
• Mitochondrial Reactive Oxygen Species Trigger Calcium Increases During Hypoxia in Pulmonary Arterial Myocytes

  2002cited by this paper
• Mutations in the Kv beta 2 binding site for NADPH and their effects on Kv1.4.

  2001cited by this paper
• NO and reactive oxygen species are involved in biphasic hypoxic vasoconstriction of isolated rabbit lungs.

  2001cited by this paper
• Nitric oxide production in the hypoxic lung.

  2001cited by this paper
• Model for Hypoxic Pulmonary Vasoconstriction Involving Mitochondrial Oxygen Sensing

  2001cited by this paper
• Mutations in the Kvβ2 Binding Site for NADPH and Their Effects on Kv1.4*

  2001cited by this paper
• Oxygen-sensitive K(+) channel(s): where and what?

  2001cited by this paper
• Glucose‐6‐phosphate dehydrogenase deficiency promotes endothelial oxidant stress and decreases endothelial nitric oxide bioavailability

  2001cited by this paper
• Binding of Pyridine Nucleotide Coenzymes to the β-Subunit of the Voltage-sensitive K+ Channel*

  2001cited by this paper
• Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor

  2001cited by this paper
• Voltage‐independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat

  2000cited by this paper
• A flavoprotein mechanism appears to prevent an oxygen-dependent inhibition of cGMP-associated nitric oxide-elicited relaxation of bovine coronary arteries.

  1999cited by this paper
• Regulation of NO-elicited pulmonary artery relaxation and guanylate cyclase activation by NADH oxidase and SOD.

  1999cited by this paper
• Regulation of NO-elicited pulmonary artery relaxation and guanylate cyclase activation by NADH oxidase and SOD.

  1999cited by this paper
• NADPH and heme redox modulate pulmonary artery relaxation and guanylate cyclase activation by NO.

  1999cited by this paper
• Modulation of voltage-dependent K+ channel by redox potential in pulmonary and ear arterial smooth muscle cells of the rabbit

  1997cited by this paper
• Differential oxygen sensitivity of calcium channels in rabbit smooth muscle cells of conduit and resistance pulmonary arteries.

  1996cited by this paper
• Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery.

  1996cited by this paper
• The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels

  1995cited by this paper
• Different modulation of Ca-activated K channels by the intracellular redox potential in pulmonary and ear arterial smooth muscle cells of the rabbit

  1995cited by this paper
• NADH and NAD modulates Ca2+-activated K+ channels in small pulmonary arterial smooth muscle cells of the rabbit

  1994cited by this paper
• EDRF suppresses an unidentified vasoconstrictor mechanism in hypertensive rat lungs.

  1993cited by this paper
• Effects of hypoxia on endothelium-dependent relaxation of rat pulmonary artery.

  1990cited by this paper
• Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants.

  1988cited by this paper
• Redox status in the control of pulmonary vascular tone.

  1986cited by this paper
• Inhibition of Hypoxic Pulmonary Vasoconstriction by Calcium Antagonists in Isolated Rat Lungs

  1976cited by this paper

• Targeting Mitochondrial Metabolic Dysfunction in Pulmonary Hypertension: Toward New Therapeutic Approaches?

  2023influential citation
• Mitochondrial Metabolism, Redox, and Calcium Homeostasis in Pulmonary Arterial Hypertension

  2022cites this paper
• NADPH oxidase in the vasculature: Expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension.

  2019cites this paper
• Hexose monophosphate shunt, the role of its metabolites and associated disorders: A review

  2019cites this paper
• EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids.

  2017cites this paper
• Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension.

  2017cites this paper
• Physiological role of reactive oxygen species as promoters of natural defenses

  2017cites this paper
• Protein Expression by Human Pulmonary Artery Smooth Muscle Cells Containing a BMPR2 Mutation and the Action of ET-1 as Determined by Proteomic Mass Spectrometry.

  2015cites this paper
• Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension.

  2015cites this paper
• Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure

  2014cites this paper
• Regulation of cellular gas exchange, oxygen sensing, and metabolic control.

  2013cites this paper
• Tissue localization of nanoparticles is altered due to hypoxia resulting in poor efficacy of curcumin nanoparticles in pulmonary hypertension.

  2012cites this paper
• Glucose-6-Phosphate Dehydrogenase and NADPH Redox Regulates Cardiac Myocyte L-Type Calcium Channel Activity and Myocardial Contractile Function

  2012cites this paper
• Hypoxic pulmonary vasoconstriction.

  2012influential citation
• Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery.

  2012cites this paper
• Oxygen-dependent regulation of nitric oxide production by inducible nitric oxide synthase.

  2011cites this paper
• Mitochondrial Reactive Oxygen Species and Redox State in Pulmonary Vascular O2 Sensing

  2011cites this paper
• Glucose-6-Phosphate Dehydrogenase Is a Regulator of Vascular Smooth Muscle Contraction

  2011cites this paper
• Activation of Glucose-6-phosphate Dehydrogenase Promotes Acute Hypoxic Pulmonary Artery Contraction*

  2010cites this paper
• Redox regulation of guanylate cyclase and protein kinase G in vascular responses to hypoxia.

  2010cites this paper
• Redox signaling and reactive oxygen species in hypoxic pulmonary vasoconstriction.

  2010cites this paper
• Oxidant-Redox Regulation of Pulmonary Vascular Responses to Hypoxia and Nitric Oxide-cGMP Signaling

  2010cites this paper
• pO(2)-dependent NO production determines OPPC activity in macrophages.

  2010cites this paper
• Differential Changes of Glutathione Levels in Astrocytes and Neurons in Ischemic Brains by Two-Photon Imaging

  2010cites this paper
• A new strategy to improve the efficiency and sustainability of Candida parapsilosis catalyzing deracemization of (R,S)-1-phenyl-1,2-ethanediol under non-growing conditions: increase of NADPH availability.

  2009cites this paper
• Changes in Oxygen Tension Rapidly and Reversibly Regulate Macrophage Nitric Oxide Production

  2009influential citation
• Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells.

  2009cites this paper
• Selective inhibition of guanylate cyclase prevents impairment of hypoxic pulmonary vasoconstriction in endotoxemic mice.

  2009cites this paper
• Reactive oxygen species and the control of vascular function.

  2009cites this paper
• Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells.

  2009cites this paper
• A twist in the tail: synergism between mitochondria and NADPH oxidase in the hypoxia-induced elevation of reactive oxygen species in pulmonary artery.

  2008influential citation
• Oxygen sensors in context.

  2008cites this paper
• Glucose-6-phosphate dehydrogenase: a novel therapeutic target in cardiovascular diseases.

  2008cites this paper
• The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: A review

  2008cites this paper
• Oxidant and Redox Signaling in Vascular Oxygen Sensing: Implications for Systemic and Pulmonary Hypertension

  2008influential citation
• EFFETS DES LIPOPROTÉINES DE FAIBLE DENSITÉ OXYDÉES SUR LES CELLULES OSTÉOBLASTIQUES

  2008cites this paper
• Cytosolic NAD(P)H Regulation of Redox Signaling and Vascular Oxygen Sensing

  2007cites this paper
• Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species.

  2006cites this paper
• Commentary on "Hypoxia, hypoxic signaling, tissue damage, and detection of reactive oxygen species (ROS)".

  2006cites this paper
• Effects of glucose concentration on redox status in rat primary cortical neurons under hypoxia.

  2006cites this paper
• Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species.

  2006cites this paper
• Last Word: Point:Counterpoint authors respond to commentaries on “Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species”

  2006cites this paper
• Oxygen sensors in hypoxic pulmonary vasoconstriction.

  2006cites this paper
• The following letters are in response to the Point : Counterpoint series “ Hypoxic pulmonary vasoconstriction

  2006influential citation
• Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species.

  2006cites this paper
• Oxidant and redox signaling in vascular oxygen sensing mechanisms: basic concepts, current controversies, and potential importance of cytosolic NADPH.

  2005cites this paper