Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of Hepatology

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jhep.2009.07.008PMID 19695729
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Peginterferon Alfa-2a and Ribavirin for 24 Weeks in Hepatitis C Type 1 and 4 Patients With Rapid Virological Response

  2009cited by this paper
• Peginterferon alfa-2a and ribavirin for 24 weeks in hepatitis C type 1 and 4 patients with rapid virological response.

  2008cited by this paper
• Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin.

  2008cited by this paper
• Insulin resistance impairs rapid virologic response in HIV/hepatitis C virus coinfected patients on peginterferon-alfa-2a

  2008cited by this paper
• 835 TIME TO HCVRNA UNDETECTABILITY SUPERSEDES BASELINE FACTORS IN PREDICTING SVR IN PATIENTS WITH HCV GENOTYPE 1

  2008cited by this paper
• Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis.

  2008cited by this paper
• Defective hepatic response to interferon and activation of suppressor of cytokine signaling 3 in chronic hepatitis C.

  2007cited by this paper
• Individualized treatment duration for hepatitis C genotype 1 patients: A randomized controlled trial

  2007cited by this paper
• Clearance of HCV Improves Insulin Resistance, Beta-Cell Function, and Hepatic Expression of Insulin Receptor Substrate 1 and 2

  2007cited by this paper
• Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus–related chronic hepatitis: Insulin resistance and response to antiviral therapy

  2007cited by this paper
• Predictive value of rapid virological response and early virological response on sustained virological response in HCV patients treated with pegylated interferon α‐2a and ribavirin

  2007cited by this paper
• Rapid and early virological response to chronic hepatitis C treatment with IFN alpha2b or PEG-IFN alpha2b plus ribavirin in HIV/HCV co-infected patients.

  2007cited by this paper
• Treatment extension to 72 weeks of peginterferon and ribavirin in hepatitis c genotype 1–infected slow responders

  2007cited by this paper
• Early identification of HCV genotype 1 patients responding to 24 weeks peginterferon α‐2a (40 kd)/ribavirin therapy

  2006cited by this paper
• Does a lower insulin resistance affect antiviral therapy response in patients suffering from HCV related chronic hepatitis?

  2006cited by this paper
• Correlation between insulin resistance and hepatitis C viral load

  2006cited by this paper
• Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.

  2005cited by this paper
• Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C

  2005cited by this paper
• Insulin resistance is associated with liver fibrosis in non-diabetic chronic hepatitis C patients.

  2005cited by this paper
• Predicting sustained virological responses in chronic hepatitis C patients treated with peginterferon alfa-2a (40 KD)/ribavirin.

  2005cited by this paper
• Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3.

  2005cited by this paper
• Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance.

  2004cited by this paper
• Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose.

  2004cited by this paper
• Early virologic response to treatment with peginterferon alfa‐2b plus ribavirin in patients with chronic hepatitis C

  2003cited by this paper
• Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection.

  2002cited by this paper
• Clinical significance of the insulin resistance index as assessed by homeostasis model assessment.

  2001cited by this paper
• Hepatitis C virus core protein induces hepatic steatosis in transgenic mice.

  1997cited by this paper
• Chronic hepatitis: morphology and nomenclature.

  1994cited by this paper
• Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man

  1985cited by this paper
• For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group

  year unknowncited by this paper

• The relation between SNPs in the NME1 gene and response to sofosbuvir in Egyptian patients with chronic HCV

  2023cites this paper
• The Role of Vitamin D and Vitamin D Binding Protein in Chronic Liver Diseases

  2022cites this paper
• Gene silencing approaches for the treatment of hepatitis C virus infection

  2020cites this paper
• COVID-19: Importancia de la resistencia a la insulina en la respuesta a la terapia antiviral con interferón

  2020cites this paper
• Effects of vitamin D supplements in patients with chronic hepatitis C: a randomized, multi-center, open label study

  2019cites this paper
• Evaluation of Safety and Effectiveness of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Switch Followed by Ledipasvir/Sofosbuvir HCV Therapy in HIV–HCV Coinfection

  2019cites this paper
• Insulin resistance does not impair response of chronic hepatitis C virus to direct-acting antivirals, and improves with the treatment

  2019cites this paper
• Hepatitis C Direct Acting Antivirals and Ribavirin Modify Lipid but not Glucose Parameters

  2019cites this paper
• INSULIN RESISTANCE REDUCTION AFTER SUSTAINED VIROLOGICAL RESPONSE WITH DIRECT ACTING ANTIVIRAL:NOT EVERY POPULATION IMPROVES.

  2018cites this paper
• Efficacy of vitamin D supplementation in combination with conventional antiviral therapy in patients with chronic hepatitis C infection: a meta‐analysis of randomised controlled trials

  2018cites this paper
• Glycogen Synthase Kinase 3β Enhances Hepatitis C Virus Replication by Supporting miR-122

  2018cites this paper
• Successful Withdrawal of Insulin Therapy After Post-Treatment Clearance of Hepatitis C Virus in a Man with Type 2 Diabetes

  2017cites this paper
• Mortality associated with gastrointestinal bleeding in children: A retrospective cohort study

  2017cites this paper
• Effects of Azilsartan, Aliskiren or their Combination on High Fat Diet-induced Non-alcoholic Liver Disease Model in Rats

  2017cites this paper
• Role of IL28B genotype in the liver stiffness increase in untreated patients with chronic hepatitis C.

  2017cites this paper
• Diabetes mellitus, insulin resistance and hepatitis C virus infection: A contemporary review

  2017cites this paper
• Vitamin D in liver disease: Current evidence and potential directions.

  2017cites this paper
• Improvement of glycemic state among responders to Sofosbuvir‐based treatment regimens: Single center experience

  2017cites this paper
•  Daclatasvir plus asunaprevir dual therapy for chronic HCV genotype 1b infection: results of Turkish early access program.

  2017cites this paper
• Mechanism of Hepatitis C Virus-Induced Diabetes Mellitus.

  2017cites this paper
• Prevalence and clinical implications of IL28B genotypes in Taiwanese patients with chronic hepatitis C.

  2016cites this paper
• Improving treatment and liver fibrosis outcomes with metformin in HCV-HIV co-infected and HCV mono-infected patients with insulin resistance: study protocol for a randomized controlled trial

  2016cites this paper
• Insulin Resistance Predicts Virological Response to Interferon-&agr; in Chronic Hepatitis B Patients

  2016cites this paper
• Hepatitis C and insulin action: An intimate relationship.

  2016cites this paper
• Insulin resistance and anti‐hepatitis C virus therapy

  2016cites this paper
• Retrospective serum gamma-glutamyl transferase with treatment outcome in chronic hepatitis B patients

  2015cites this paper
• Depression is not associated with peripheral insulin resistance in patients with chronic hepatitis C infection

  2015cites this paper
• Hepatitis C virus infection, metabolic disorders and non-alcoholic fatty liver disease: a literature review.

  2015cites this paper
• Association of serum gamma-glutamyl transferase with treatment outcome in chronic hepatitis B patients.

  2015cites this paper
• Evaluating the Effects of the Components of Metabolic Syndrome, Fatty LiverandLiverFunctiononChronic Hepatitis C: Data Analysis of Adult Health Examinations

  2015cites this paper
• Impact of insulin resistance and lipid profile abnormalities on virological response to treatment of hepatitis C virus

  2015cites this paper
• Insulin resistance as a predictor of early virologic response to HCV therapy among chronic HCV Egyptian Patients

  2015cites this paper
• HOMA, BMI, and Serum Leptin Levels Variations during Antiviral Treatment Suggest Virus-Related Insulin Resistance in Noncirrhotic, Nonobese, and Nondiabetic Chronic Hepatitis C Genotype 1 Patients

  2015cites this paper
• S2k-Leitlinie nicht alkoholische Fettlebererkrankungen

  2015cites this paper
• The impact of pegylated interferon and ribavirin combination treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients

  2014cites this paper
• Revisiting predictors of virologic response to PEGIFN + RBV therapy in HIV‐/HCV‐coinfected patients: the role of metabolic factors and elevated GGT levels

  2014cites this paper
• Successful Hepatitis C Antiviral Therapy Induces Remission of Type 2 Diabetes: A Case Report

  2014cites this paper
• Interaction between hepatitis C virus and metabolic factors.

  2014cites this paper
• Vitamin D deficiency in chronic liver disease.

  2014cites this paper
• Hepatitis C and lipid metabolism, hepatic steatosis, and NAFLD: still important in the era of direct acting antiviral therapy?

  2014cites this paper
• Insulin resistance and steatosis in HBV-HCV co-infected patients: Role of PNPLA3 polymorphisms and impact on liver fibrosis progression.

  2014cites this paper
• Insulin Sensitivity and Variability in Hepatitis C Virus Infection Using Direct Measurement

  2013cites this paper
• Association between insulin resistance and sustained virologic response in hepatitis C treatment, genotypes 1 versus 2 and 3: systematic literature review and meta-analysis

  2013cites this paper
• Are metabolic factors still important in the era of direct antiviral agents in patients with chronic hepatitis C?

  2013cites this paper
• Metabolic Factors and Chronic Hepatitis C: A Complex Interplay

  2013cites this paper
• Estimates of HCV-1 Patients Attaining RVR Following Dual Therapy with Peg-Interferon and Ribavirin

  2013cites this paper
• Assessment of factors associated with pre‐diabetes in HCV infection including direct and dynamic measurements of insulin action

  2012cites this paper
• Impact of Insulin Resistance on HCV Treatment Response and Impact of HCV Treatment on Insulin Sensitivity Using Direct Measurements of Insulin Action

  2012cites this paper
• Vitamin D Levels and Il28B Polymorphisms are Related to Rapid Virological Response to Standard of Care in Genotype 1 Chronic Hepatitis C

  2012cites this paper
• The interaction among insulin resistance, liver fibrosis and early virological response in Egyptian patients with chronic hepatitis C

  2012cites this paper
• The Impact of Host Factors on Management of Hepatitis C Virus

  2012cites this paper
• Post-load insulin resistance does not predict virological response to treatment of chronic hepatitis C patients without the metabolic syndrome.

  2012cites this paper
• The impact of fibrosis and steatosis on early viral kinetics in HCV genotype 1–infected patients treated with Peg‐IFN‐alfa‐2a and ribavirin

  2012cites this paper
• Association between the epidermal growth factor rs4444903 G/G genotype and advanced fibrosis at a young age in chronic hepatitis C.

  2012cites this paper
• A Lower Serum Gamma-Glutamyltransferase Level Does Not Predict a Sustained Virological Response in Patients with Chronic Hepatitis C Genotype 1

  2012cites this paper
• [Efficacy of peginterferon and ribavirin combination therapy of chronic hepatitis C: a pooled analysis].

  2012cites this paper
• Insulin resistance in patients with cirrhosis and portal hypertension.

  2012cites this paper
• Association of insulin resistance, viral load, and adipokine levels with liver histology in patients with chronic hepatitis C: an observational, multicenter study in Turkey

  2012cites this paper
• The interaction between insulin resistance, liver fibrosis and early virological response in Egyptian patients with chronic hepatitis C.

  2012cites this paper
• Possible involvement of angiogenesis in chronic liver diseases: interaction among renin-angiotensin-aldosterone system, insulin resistance and oxidative stress.

  2012cites this paper
• Insulin Resistance Impairs Viral Dynamics Independently of Ethnicity or Genotypes

  2012cites this paper
• Interleukin-28B genetic variants in identification of hepatitis C virus genotype 1 patients responding to 24 weeks peginterferon/ribavirin.

  2012cites this paper
• Vitamin D improves viral response in hepatitis C genotype 2-3 naïve patients.

  2012cites this paper
• Steatosis and insulin resistance in response to treatment of chronic hepatitis C

  2012cites this paper
• Relative Impact of Ribavirin Monitoring and HIV Coinfection on Sustained Virological Response in Patients with Chronic Hepatitis C

  2011cites this paper
• Ribavirin concentration in the later stages of 48 week pegylated interferon-alpha2b plus ribavirin therapy for chronic hepatitis C is useful for predicting virological response.

  2011cites this paper
• Insulin resistance and chronic liver disease.

  2011cites this paper
• Use of HOMA‐IR in hepatitis C

  2011cites this paper
• Role of interleukin‐28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients

  2011cites this paper
• The homeostasis model assessment of the insulin resistance score is not predictive of a sustained virological response in chronic hepatitis C patients

  2011cites this paper
• Metabolic alterations and chronic hepatitis C: treatment strategies

  2011cites this paper
• 'Easy to treat' genotypes were not created equal: can rapid virological response (RVR) level the playing field?

  2011cites this paper
• Insulin resistance in non-diabetic patients with chronic hepatitis C: what does it mean?

  2011cites this paper
• Fibrosis severity and mannan-binding lectin (MBL)/MBL-associated serine protease 1 (MASP-1) complex in HCV-infected patients.

  2011cites this paper
• Role of Interleukin 28B rs12979860 C/T Polymorphism on the Histological Outcome of Chronic Hepatitis C: Relationship with Gender and Viral Genotype

  2011cites this paper
• Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: a meta-analysis.

  2011cites this paper
• Insulin resistance and hepatitis C: an evolving story

  2011cites this paper
• Vitamin D supplementation improves sustained virologic response in chronic hepatitis C (genotype 1)-naïve patients.

  2011cites this paper
• Gamma-glutamyltranspeptidase in predicting sustained virological response in individuals with chronic hepatitis C.

  2011cites this paper
• Changes in insulin sensitivity and body weight during and after peginterferon and ribavirin therapy for hepatitis C.

  2011cites this paper
• Response‐guided peg‐interferon plus ribavirin treatment duration in chronic hepatitis C: Meta‐analyses of randomized, controlled trials and implications for the future

  2011cites this paper
• IL28B polymorphisms, IP‐10 and viral load predict virological response to therapy in chronic hepatitis C

  2011cites this paper
• Meta‐analysis: insulin resistance and sustained virological response in hepatitis C

  2011cites this paper
• Current understanding of insulin resistance in hepatitis C

  2011cites this paper
• Pioglitazone improves virological response to peginterferon α‐2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance

  2010cites this paper
• Potential treatment options and future research to increase hepatitis C virus treatment response rate

  2010cites this paper
• Comparison of surrogate and direct measurement of insulin resistance in chronic hepatitis C virus infection: Impact of obesity and ethnicity

  2010cites this paper
• GUTJNL228262 1139..1151

  year unknowncites this paper
• Clinical Interventions in Aging Dovepress Correlation between Vitamin D Levels and Apoptosis in Geriatric Patients Infected with Hepatitis C Virus Genotype 4 Sami a Gabr 1,2 Ayman a Ghfar

  year unknowncites this paper