Nanopolystyrene at predicted environmental concentration enhances microcystin-LR toxicity by inducing intestinal damage in Caenorhabditis elegans.

We employed nematode Caenorhabditis elegans to determine the combinational effect between nanopolystyrene at predicted environmental concentration and microcystin-LR (MC-LR). Prolonged exposure to nanopolystyrene (1 μg/L) increased MC-LR (0.1 μg/L) toxicity in reducing brood size and locomotion behavior and in inducing oxidative stress. Moreover, the adsorption of MC-LR by nanopolystyrene particles played an important role in inducing the enhancement in MC-LR toxicity by nanopolystyrene particles. Additionally, only exposure to resuspension of nanopolystyrene (1 μg/L) caused the increased intestinal permeability in MC-LR (0.1 μg/L) exposed nematodes. Our data indicates the potential of nanopolystyrene at predicted environmental concentration in enhancing MC-LR toxicity on environmental organisms.

• Publication year

  2019

• Venue

  Ecotoxicology and Environmental Safety

• Publication date

  2019-11-15

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.ecoenv.2019.109568PMID 31437729
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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