Animal models for Lassa virus infection.

In humans, Lassa virus infection can result in disease with hemorrhagic manifestations and high fatality rates. There are no approved treatments or vaccines available and the inherent danger of studying Lassa virus means it can only be studied in high containment labs (BSL4). Under these conditions, mouse models are becoming an important instrument in the study of Lassa virus infection, disease and host responses. While guinea pigs and non-human primates are the critical components in assessing treatments and vaccines and have recently been used with great affect in this capacity.

• Publication year

  2019

• Venue

  Current Opinion in Virology

• Publication date

  2019-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.coviro.2019.07.005PMID 31442921
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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