Translocation of soft phytoglycogen nanoparticles through solid-state nanochannels.

Phytoglycogen nanoparticles are soft, naturally-derived nanomaterials with a highly uniform size near 35 nm. Their interior is composed of a highly-branched polysaccharide core that contains more than 200% of its dry mass in water. In this work, we measure the translocation of phytoglycogen particles by observing blockade events they create when occluding solid-state nanochannels with diameters between 60 and 100 nm. The translocation signals are interpreted using Poisson-Nernst-Planck calculations with a "hardness parameter" that describes the extent to which solvent can penetrate through the interior of the particles. Theory and experiment were found to be in quantitative agreement, allowing us to extract physical characteristics of the particles on a per particle basis.

• Publication year

  2019

• Venue

  Journal of materials chemistry. B

• Publication date

  2019-10-23

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1039/c9tb01048cPMID 31465081
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Unusual polysaccharide rheology of aqueous dispersions of soft phytoglycogen nanoparticles.

  2018cited by this paper
• Thermally Robust Non-Wetting Ni-PTFE Electrodeposited Nanocomposite

  2018cited by this paper
• Effects of Instrumental Filters on Electrochemical Measurement of Single‐Nanoparticle Collision Dynamics

  2018cited by this paper
• Equilibrium Swelling, Interstitial Forces, and Water Structuring in Phytoglycogen Nanoparticle Films.

  2017cited by this paper
• Voltage-Rectified Current and Fluid Flow in Conical Nanopores.

  2016cited by this paper
• Structure and Hydration of Highly-Branched, Monodisperse Phytoglycogen Nanoparticles.

  2016cited by this paper
• Land Use History Shifts In Situ Fungal and Bacterial Successions following Wheat Straw Input into the Soil

  2015cited by this paper
• Use of solid-state nanopores for sensing co-translocational deformation of nano-liposomes.

  2015cited by this paper
• Gold nanorod translocations and charge measurement through solid-state nanopores.

  2014cited by this paper
• Polymer translocation: the first two decades and the recent diversification.

  2014cited by this paper
• Gold nanoparticle translocation dynamics and electrical detection of single particle diffusion using solid-state nanopores.

  2013cited by this paper
• Differentiation of short, single-stranded DNA homopolymers in solid-state nanopores.

  2013cited by this paper
• Fast and automatic processing of multi-level events in nanopore translocation experiments.

  2012cited by this paper
• DNA translocation through graphene nanopores.

  2010cited by this paper
• Nanopore DNA sequencing with MspA

  2010cited by this paper
• Plasmodesmata: gateways to local and systemic virus infection.

  2010cited by this paper
• The Origins of Lactase Persistence in Europe

  2009cited by this paper
• Poisson-Nernst-Planck Models of Nonequilibrium Ion Electrodiffusion through a Protegrin Transmembrane Pore

  2009cited by this paper
• The Spread of Rice Dwarf Virus among Cells of Its Insect Vector Exploits Virus-Induced Tubular Structures

  2006cited by this paper
• Simulation of polymer translocation through protein channels.

  2006cited by this paper
• Movement of Macromolecules in Plant Cells Through Plasmodesmata

  2006cited by this paper
• Counting polymers moving through a single ion channel

  1994cited by this paper
• Measurements of bandgap narrowing in Si bipolar transistors

  1976cited by this paper

• Dual-Functionalized Glass Micropipette Sensor for Simultaneous High Sensitivity Detection of Cancer Biomarkers.

  2025cites this paper
• Solid-State Nanopore/Nanochannel Sensing of Single Entities

  2023influential citation
• Translocation, Rejection and Trapping of Polyampholytes

  2022cites this paper
• Combining dynamic Monte Carlo with machine learning to study nanoparticle translocation.

  2022cites this paper
• Globular Polyampholytes: Structure and Translocation

  2021cites this paper
• Tailoring CO2-Activated Ion Nanochannels Using Macrocyclic Pillararenes.

  2021cites this paper
• Predicting the Optical and Electrical Properties of Polymer Nanocomposites

  2020cites this paper