HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to human brain microvascular endothelial cells via gp41 core-induced membrane activities.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Biochemical Journal

• Publication date

  2011-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BJ20110218PMID 21668410
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Development of Peptide and Small‐Molecule HIV‐1 Fusion Inhibitors that Target gp41

  2010cited by this paper
• HIV-1 gp41 fusion intermediate: a target for HIV therapeutics.

  2010cited by this paper
• Identification of a gp41 Core-Binding Molecule with Homologous Sequence of Human TNNI3K-Like Protein as a Novel Human Immunodeficiency Virus Type 1 Entry Inhibitor

  2010cited by this paper
• A recombinant mimetics of the HIV-1 gp41 prehairpin fusion intermediate fused with human IgG Fc fragment elicits neutralizing antibody response in the vaccinated mice.

  2010cited by this paper
• Conformational stability and membrane interaction of the full-length ectodomain of HIV-1 gp41: implication for mode of action.

  2009cited by this paper
• Interaction of HIV-1 gp41 Core with NPF Motif in Epsin

  2008cited by this paper
• Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells requires protein kinase C‐α activation

  2008cited by this paper
• HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to HBMEC.

  2007cited by this paper
• Identification of the HIV-1 gp41 Core-binding Motif in the Scaffolding Domain of Caveolin-1*

  2007cited by this paper
• Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended.

  2006cited by this paper
• Alanine Scanning Mutants of the HIV gp41 Loop*

  2005cited by this paper
• Role of Hydrophobic Residues in the Central Ectodomain of gp41 in Maintaining the Association between Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Subunits gp120 and gp41

  2004cited by this paper
• The C- and the N-terminal Regions of Glycoprotein 41 Ectodomain Fuse Membranes Enriched and Not Enriched with Cholesterol, Respectively*

  2004cited by this paper
• Enfuvirtide, an HIV-1 fusion inhibitor, for drug-resistant HIV infection in North and South America.

  2003cited by this paper
• The entry of entry inhibitors: A fusion of science and medicine

  2003cited by this paper
• Studies of cerebral endothelium by scanning and high-voltage electron microscopy.

  2003cited by this paper
• HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation.

  2003cited by this paper
• Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells.

  2003cited by this paper
• Binding of Candida albicans enolase to plasmin(ogen) results in enhanced invasion of human brain microvascular endothelial cells.

  2003cited by this paper
• Genetic Evidence that Interhelical Packing Interactions in the gp41 Core Are Critical for Transition of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein to the Fusion-Active State

  2002cited by this paper
• Human Immunodeficiency Virus Type 1 Enters Brain Microvascular Endothelia by Macropinocytosis Dependent on Lipid Rafts and the Mitogen-Activated Protein Kinase Signaling Pathway

  2002cited by this paper
• Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion.

  2002cited by this paper
• Mechanisms of viral membrane fusion and its inhibition.

  2001cited by this paper
• Cellular mechanisms of microbial proteins contributing to invasion of the blood–brain barrier

  2001cited by this paper
• Crosstalk Between Components of the Blood Brain Barrier and Cells of the CNS in Microglial Activation in AIDS

  2001cited by this paper
• Structural and Functional Analysis of Interhelical Interactions in the Human Immunodeficiency Virus Type 1 gp41 Envelope Glycoprotein by Alanine-Scanning Mutagenesis

  2001cited by this paper
• Traversal of Candida albicans across Human Blood-Brain Barrier In Vitro

  2001cited by this paper
• N36, a synthetic N-terminal heptad repeat domain of the HIV-1 envelope protein gp41, is an activator of human phagocytes.

  2000cited by this paper
• Cross-linking of CD4 induces cytoskeletal association of CD4 and p56lck

  2000cited by this paper
• Risk Factors for Cryptococcal Meningitis in HIV-Infected Patients

  1999cited by this paper
• Immunoultrastructural expression of intercellular adhesion molecule-1 in endothelial cell vesiculotubular structures and vesiculovacuolar organelles in blood-brain barrier development and injury

  1999cited by this paper
• Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals.

  1999cited by this paper
• Isolation, Characterization, and Localization of a Capsule-Associated Gene, CAP10, of Cryptococcus neoformans

  1999cited by this paper
• Interactions between HIV-1 gp41 Core and Detergents and Their Implications for Membrane Fusion*

  1999cited by this paper
• Isolation of the Third Capsule-Associated Gene,CAP60, Required for Virulence in Cryptococcus neoformans

  1998cited by this paper
• Actin-Dependent Receptor Colocalization Required for Human Immunodeficiency Virus Entry into Host Cells

  1998cited by this paper
• HIV entry and its inhibition.

  1998cited by this paper
• Invasion of brain microvascular endothelial cells by group B streptococci

  1997cited by this paper
• Atomic structure of the ectodomain from HIV-1 gp41

  1997cited by this paper
• Core structure of gp41 from the HIV envelope glycoprotein.

  1997cited by this paper
• Atomic structure of a thermostable subdomain of HIV-1 gp41.

  1997cited by this paper
• Bovine brain microvascular endothelial cells transfected with SV40-large T antigen: Development of an immortalized cell line to study pathophysiology of CNS disease

  1997cited by this paper
• A trimeric structural subdomain of the HIV-1 transmembrane glycoprotein.

  1997cited by this paper
• vaccine in The Netherlands . persons vaccinated with inactivated poliovirus Poliovirus-specific immunoglobulin A in

  1997cited by this paper
• The second capsule gene of cryptococcus neoformans, CAP64, is essential for virulence

  1996cited by this paper
• A General Model for the Surface Glycoproteins of HIV and Other Retroviruses

  1995cited by this paper
• Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans

  1995cited by this paper
• A trimeric structural domain of the HIV-1 transmembrane glycoprotein

  1995cited by this paper
• HIV infection of human brain capillary endothelial cells--implications for AIDS dementia.

  1994cited by this paper
• Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.

  1994cited by this paper
• HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells.

  1994cited by this paper
• Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein

  1993cited by this paper
• HIV-1 inhibition by a peptide

  1993cited by this paper
• Nested fullerene-like structures

  1993cited by this paper
• Cryptococcal meningitis and AIDS.

  1993cited by this paper
• Early penetration of the blood‐brain‐barrier by HIV

  1988cited by this paper
• Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms.

  1987cited by this paper

• Effects of statins on serum sCD40, sCD146 and PAPP-An in patients with coronary heart disease

  2025cites this paper
• The pathways and the mechanisms by which Cryptococcus enters the brain

  2024cites this paper
• Host cell membrane microdomains and fungal infection

  2021cites this paper
• Mutations of Glu560 within HIV-1 Envelope Glycoprotein N-terminal heptad repeat region contribute to resistance to peptide inhibitors of virus entry

  2019cites this paper
• HIV-1 gp41-enhanced binding of Cryptococcus neoformans to human brain microvascular endothelial cells is blocked by SBi4211

  2019influential citation
• CD44-mediated monocyte transmigration across Cryptococcus neoformans-infected brain microvascular endothelial cells is enhanced by HIV-1 gp41-I90 ectodomain

  2016cites this paper
• Real‐time in vivo imaging reveals the ability of neutrophils to remove Cryptococcus neoformans directly from the brain vasculature

  2016cites this paper
• Human‐Based In Vitro Brain Endothelial Cell Models

  2015cites this paper
• Alpha7 nicotinic acetylcholine receptor is required for blood-brain barrier injury-related CNS disorders caused by Cryptococcus neoformans and HIV-1 associated comorbidity factors

  2015influential citation
• Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV.

  2015cites this paper
• Circulating Brain Microvascular Endothelial Cells (cBMECs) as Potential Biomarkers of the Blood–Brain Barrier Disorders Caused by Microbial and Non-Microbial Factors

  2013cites this paper
• Cryptococcus neoformans-Derived Microvesicles Enhance the Pathogenesis of Fungal Brain Infection

  2012cites this paper