Diversity and evolution of actin-dependent phenotypes.

The actin cytoskeleton governs a vast array of core eukaryotic phenotypes that include cell movement, endocytosis, vesicular trafficking, and cytokinesis. Although the basic principle underlying these processes is strikingly simple - actin monomers polymerize into filaments that can depolymerize back into monomers - eukaryotic cells have sophisticated and layered control systems to regulate actin dynamics. The evolutionary origin of these complex systems is an area of active research. Here, we review the regulation and diversity of actin networks to provide a conceptual framework for cell biologists interested in evolution and for evolutionary biologists interested in actin-dependent phenotypes.

• Publication year

  2019

• Venue

  Current Opinion in Genetics and Development

• Publication date

  2019-08-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.gde.2019.07.016PMID 31466039
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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