Diversity of Bacterial Chemosensory Arrays.

Chemotaxis is crucial for the survival of bacteria, and the signaling systems associated with it exhibit a high level of evolutionary conservation. The architecture of the chemosensory array and the signal transduction mechanisms have been extensively studied in Escherichia coli. More recent studies have revealed a vast diversity of the chemosensory system among bacteria. Unlike E. coli, some bacteria assemble more than one chemosensory array and respond to a broader spectrum of environmental and internal stimuli. These chemosensory arrays exhibit a great variability in terms of protein composition, cellular localization, and functional variability. Here, we present recent findings that emphasize the extent of diversity in chemosensory arrays and highlight the importance of studying chemosensory arrays in bacteria other than the common model organisms.

• Publication year

  2019

• Venue

  Trends in Microbiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.tim.2019.08.002PMID 31473052
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins

  2019cited by this paper
• Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution

  2019cited by this paper
• Bacterial chemotaxis coupling protein: Structure, function and diversity.

  2019cited by this paper
• Cross Talk between Chemosensory Pathways That Modulate Chemotaxis and Biofilm Formation

  2019cited by this paper
• Repurposing a macromolecular machine: Architecture and evolution of the F7 chemosensory system

  2019cited by this paper
• Chemotaxis Arrays in Vibrio Species and Their Intracellular Positioning by the ParC/ParP System

  2018cited by this paper
• Functional Annotation of Bacterial Signal Transduction Systems: Progress and Challenges

  2018cited by this paper
• Colonization, localization, and inflammation: the roles of H. pylori chemotaxis in vivo.

  2018cited by this paper
• Baseplate variability of Vibrio cholerae chemoreceptor arrays

  2018cited by this paper
• CryoEM-based hybrid modeling approaches for structure determination.

  2018cited by this paper
• Cellular targeting and segregation of bacterial chemosensory systems.

  2018cited by this paper
• Structural and Proteomic Changes in Viable but Non-culturable Vibrio cholerae

  2018cited by this paper
• Progress and Potential of Electron Cryotomography as Illustrated by Its Application to Bacterial Chemoreceptor Arrays.

  2017cited by this paper
• Galangin Reduces the Loss of Dopaminergic Neurons in an LPS-Evoked Model of Parkinson’s Disease in Rats

  2017cited by this paper
• Flexible Hinges in Bacterial Chemoreceptors

  2017cited by this paper
• Recent Advances and Future Prospects in Bacterial and Archaeal Locomotion and Signal Transduction

  2017cited by this paper
• His-Tag-Mediated Dimerization of Chemoreceptors Leads to Assembly of Functional Nanoarrays

  2017cited by this paper
• Chemoreceptor-based signal sensing.

  2017cited by this paper
• Is there any crosstalk between the chemotaxis and virulence induction signaling in Agrobacterium tumefaciens?

  2017cited by this paper
• Coupling chemosensory array formation and localization

  2017cited by this paper
• Two-component systems required for virulence in Pseudomonas aeruginosa

  2017cited by this paper
• Assigning chemoreceptors to chemosensory pathways in Pseudomonas aeruginosa

  2017cited by this paper
• Sensory Repertoire of Bacterial Chemoreceptors

  2017cited by this paper
• Emergent properties of bacterial chemotaxis pathway.

  2017cited by this paper
• Evolutionary Genomics Suggests That CheV Is an Additional Adaptor for Accommodating Specific Chemoreceptors within the Chemotaxis Signaling Complex

  2016cited by this paper
• The Borrelia burgdorferi CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle

  2016cited by this paper
• Differential Localization of Chemotactic Signaling Arrays during the Lifecycle of Vibrio parahaemolyticus

  2016cited by this paper
• Chemotaxis cluster 1 proteins form cytoplasmic arrays in Vibrio cholerae and are stabilized by a double signaling domain receptor DosM

  2016cited by this paper
• The source of high signal cooperativity in bacterial chemosensory arrays

  2016cited by this paper
• Borrelia burgdorferi CheY2 Is Dispensable for Chemotaxis or Motility but Crucial for the Infectious Life Cycle of the Spirochete

  2016cited by this paper
• Structural conservation of chemotaxis machinery across Archaea and Bacteria.

  2015cited by this paper
• Pseudomonas chemotaxis.

  2015cited by this paper
• RpoS and quorum sensing control expression and polar localization of Vibrio cholerae chemotaxis cluster III proteins in vitro and in vivo

  2015cited by this paper
• Positioning of bacterial chemoreceptors.

  2015cited by this paper
• Chemodetection and Destruction of Host Urea Allows Helicobacter pylori to Locate the Epithelium.

  2015cited by this paper
• CryoEM and computer simulations reveal a novel kinase conformational switch in bacterial chemotaxis signaling

  2015cited by this paper
• Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa

  2015cited by this paper
• Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update.

  2015cited by this paper
• Methyl-accepting chemotaxis proteins 3 and 4 are responsible for Campylobacter jejuni chemotaxis and jejuna colonization in mice in response to sodium deoxycholate.

  2014cited by this paper
• New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography

  2014cited by this paper
• Bacterial chemoreceptors of different length classes signal independently

  2014cited by this paper
• Internal Sense of Direction: Sensing and Signaling from Cytoplasmic Chemoreceptors

  2014cited by this paper
• Chemosensory signaling systems that control bacterial survival.

  2014cited by this paper
• Selective allosteric coupling in core chemotaxis signaling complexes

  2014cited by this paper
• Correlated cryogenic photoactivated localization microscopy and electron cryotomography

  2014cited by this paper
• Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling

  2014cited by this paper
• Super-Resolution Microscopy Using Standard Fluorescent Proteins in Intact Cells under Cryo-Conditions

  2014cited by this paper
• Functional Organization of a Multimodular Bacterial Chemosensory Apparatus

  2014cited by this paper
• Insights into Vibrio cholerae Intestinal Colonization from Monitoring Fluorescently Labeled Bacteria

  2014cited by this paper
• Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling.

  2013cited by this paper
• Defining a key receptor-CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS Study.

  2013cited by this paper
• Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study.

  2013cited by this paper
• The 3.2 Å resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays.

  2013cited by this paper
• Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells

  2012cited by this paper
• CheA-receptor interaction sites in bacterial chemotaxis.

  2012cited by this paper
• Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins

  2012cited by this paper
• Cellular Stoichiometry of the Chemotaxis Proteins in Bacillus subtilis

  2011cited by this paper
• Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions.

  2010cited by this paper
• Identification and characterization of the aspartate chemosensory receptor of Campylobacter jejuni

  2010cited by this paper
• Correlated light and electron cryo-microscopy.

  2010cited by this paper
• Specificity of localization and phosphotransfer in the CheA proteins of Rhodobacter sphaeroides

  2010cited by this paper
• Origins and Diversification of a Complex Signal Transduction System in Prokaryotes

  2010cited by this paper
• An MCP-like protein interacts with the MamK cytoskeleton and is involved in magnetotaxis in Magnetospirillum magneticum AMB-1.

  2010cited by this paper
• Signaling mechanisms of HAMP domains in chemoreceptors and sensor kinases.

  2010cited by this paper
• CheV: CheW-like coupling proteins at the core of the chemotaxis signaling network.

  2010cited by this paper
• Self-Organization of the Escherichia coli Chemotaxis Network Imaged with Super-Resolution Light Microscopy

  2009cited by this paper
• Universal architecture of bacterial chemoreceptor arrays

  2009cited by this paper
• Structure and signaling mechanism of Per-ARNT-Sim domains.

  2009cited by this paper
• The core signaling proteins of bacterial chemotaxis assemble to form an ultrastable complex.

  2009cited by this paper
• The MiST2 database: a comprehensive genomics resource on microbial signal transduction

  2009cited by this paper
• Bacterial chemoreceptors: high-performance signaling in networked arrays.

  2008cited by this paper
• Evolutionary genomics reveals conserved structural determinants of signaling and adaptation in microbial chemoreceptors

  2007cited by this paper
• Spatial organization of the bacterial chemotaxis system.

  2006cited by this paper
• Two different Pseudomonas aeruginosa chemosensory signal transduction complexes localize to cell poles and form and remould in stationary phase

  2006cited by this paper
• Cellular Stoichiometry of the Components of the Chemotaxis Signaling Complex

  2004cited by this paper
• Making sense of it all: bacterial chemotaxis

  2004cited by this paper
• Crosslinking snapshots of bacterial chemoreceptor squads

  2004cited by this paper
• The rotary motor of bacterial flagella.

  2003cited by this paper
• Analyses of the Roles of the Three cheA Homologs in Chemotaxis of Vibrio cholerae

  2002cited by this paper
• Phosphorylation of the Response Regulator CheV Is Required for Adaptation to Attractants during Bacillus subtilisChemotaxis*

  2001cited by this paper
• Real-Time Imaging of Fluorescent Flagellar Filaments

  2000cited by this paper
• Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor

  1999cited by this paper
• Structure of CheA, a signal-transducing histidine kinase.

  1999cited by this paper
• Detection of a Conserved α-Helix in the Kinase-docking Region of the Aspartate Receptor by Cysteine and Disulfide Scanning*

  1998cited by this paper
• Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand.

  1995cited by this paper
• Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria

  1993cited by this paper
• Flagellar rotation and the mechanism of bacterial motility

  1974cited by this paper
• Change in direction of flagellar rotation is the basis of the chemotactic response in Escherichia coli

  1974cited by this paper
• Dynamic properties of bacterial flagellar motors

  1974cited by this paper
• Dynamic properties of bacterial flagellar motors.

  1974cited by this paper
• Chemoreceptors in bacteria.

  1969cited by this paper
• Chemotaxis in Bacteria

  1966cited by this paper
• Chemotaxis in Escherichia coli.

  1965cited by this paper

• Benzoxazinoids and Plant Growth-Promoting Bacteria: A Pathway to Sustainable Agriculture

  2026cites this paper
• Agrobacterium fabrum (tumefaciens) Chemosensory System: A Typical Model of One Histidine Kinase for Two Coupling Proteins and Multiple Response Regulators

  2025cites this paper
• Phospho-mimetic CheV interacts with a subset of chemoreceptors

  2025cites this paper
• A review of molecular signaling and communication between root tissues and their endophytes

  2025cites this paper
• Morphological plasticity of endophytic Chitinophaga pinensis

  2025cites this paper
• Comparative genomics of Leptospira santarosai reveals genomic adaptations in bovine genital strains

  2025cites this paper
• Multiple input–multiple output (MIMO) designs in two-component signalling systems of Mycobacterium tuberculosis

  2025cites this paper
• Physics of bacterial chemotaxis.

  2024cites this paper
• Role of a single MCP in evolutionary adaptation of Shewanella putrefaciens for swimming in planktonic and structured environments

  2024influential citation
• The motility and chemosensory systems of Rhizobium leguminosarum, their role in symbiosis, and link to PTSNtr regulation

  2024cites this paper
• Phenotypic Variability Shapes Bacterial Responses to Opposing Gradients

  2024cites this paper
• The dual role of a novel Sinorhizobium meliloti chemotaxis protein CheT in signal termination and adaptation

  2024cites this paper
• Chemosensory systems interact to shape relevant traits for bacterial plant pathogenesis

  2024cites this paper
• Iron limitation induces motility in uropathogenic E. coli CFT073 partially through action of LpdA

  2024cites this paper
• An Azospirillum brasilense chemoreceptor that mediates nitrate chemotaxis has conditional roles in the colonization of plant roots

  2024cites this paper
• Comparison of the Antiadhesion Activity and Mechanism between Different Chiral Molecules L-Borneol and D-Borneol against Escherichia coli

  2024cites this paper
• Chemotactic Micro/Nanomotors for Biomedical Applications.

  2023cites this paper
• Altered motility in response to iron-limitation is regulated by lpdA in uropathogenic E. coli CFT073

  2023cites this paper
• New Roles for HAMP Domains: the Tri-HAMP Region of Pseudomonas aeruginosa Aer2 Controls Receptor Signaling and Cellular Localization

  2022cites this paper
• Biosurfactants and chemotaxis interplay in microbial consortium-based hydrocarbons degradation

  2022cites this paper
• Hexameric rings of the scaffolding protein CheW enhance response sensitivity and cooperativity in Escherichia coli chemoreceptor arrays

  2022cites this paper
• Leptospira interrogans Aer2: an Unusual Membrane-Bound PAS-Heme Oxygen Sensor

  2022cites this paper
• Revealing bacterial cell biology using cryo-electron tomography.

  2022cites this paper
• The evolutionary path of chemosensory and flagellar macromolecular machines in Campylobacterota

  2022cites this paper
• Substrate size-dependent conformational changes of bacterial pectin-binding protein crucial for chemotaxis and assimilation

  2022cites this paper
• Redox-based sensing controls bacterial chemotaxis to copper

  2022cites this paper
• Mechanisms of E. coli chemotaxis signaling pathways visualized using cryoET and computational approaches

  2022cites this paper
• Defining Two Chemosensory Arrays in Shewanella oneidensis

  2022cites this paper
• Effects of Organic Acids on the Chemotaxis Pro les and Biocontrol Traits of Antagonistic Bacterial Endophytes Against Root-Rot Disease in Panax Notoginseng

  2021cites this paper
• Cyclic AMP signalling and glucose metabolism mediate pH taxis by African trypanosomes

  2021cites this paper
• The Only Chemoreceptor Encoded by che Operon Affects the Chemotactic Response of Agrobacterium to Various Chemoeffectors

  2021cites this paper
• Multiple functions of flagellar motility and chemotaxis in bacterial physiology

  2021cites this paper
• Non-Genetic Diversity in Chemosensing and Chemotactic Behavior

  2021cites this paper
• Effects of organic acids on the chemotaxis profiles and biocontrol traits of antagonistic bacterial endophytes against root-rot disease in Panax notoginseng

  2021cites this paper
• Nitrate- and Nitrite-Sensing Histidine Kinases: Function, Structure, and Natural Diversity

  2021cites this paper
• Diversity of bacterial chemosensory systems.

  2021cites this paper
• Chemotactic Host-Finding Strategies of Plant Endoparasites and Endophytes

  2020influential citation
• The phosphorylated regulator of chemotaxis is crucial throughout biofilm biogenesis in Shewanella oneidensis

  2020cites this paper
• Programmed Proteolysis of Chemotaxis Proteins in Sinorhizobium meliloti: Features in the C-Terminal Region Control McpU Degradation

  2020cites this paper
• Cellular Stoichiometry of Chemotaxis Proteins in Sinorhizobium meliloti

  2020cites this paper
• Making science tangible Creating scientific animations from cryo-electron tomography data of microbiological organisms

  2020cites this paper
• Alternative Architecture of the E. coli Chemosensory Array

  2020cites this paper
• Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax volcanii, Suggesting Roles in Motility Regulation

  2020cites this paper
• The phosphorylated regulator of chemotaxis is crucial throughout biofilm biogenesis in Shewanella oneidensis

  2020cites this paper
• Deciphering the Che2 chemosensory pathway and the roles of individual Che2 proteins from Pseudomonas aeruginosa

  2020cites this paper
• A nonflagellated, predatory soil bacterium reprograms a chemosensory system to control antifungal antibiotic production via cyclic di-GMP signaling.

  2020cites this paper