The bHLH transcription factor gene AtUPB1 regulates growth by mediating cell cycle progression in Arabidopsis.

Plant growth, development and interaction with the environment involve the action of transcription factor. bHLH proteins play an essential and often conserved role in the plant kingdom. However, bHLH proteins that participate in the cell division process are less well known. Here, we report that the bHLH transcription factor gene AtUPB1 is involved in mediating cell cycle progression and root development. In yeast cells, AtUPB1 inhibits cells proliferation and the cells had increased numbers of nuclei. UPB1 overexpression decreased the expression of the cell division marker CYCB1-1, and CDKA1 expression could overcome the defect of UPB1 overexpression. Moreover, UPB1 could directly bind to the promoter region of the SIM and SMR1 genes to regulate cell cycle. These results support a new role for AtUPB1 regulating root meristem development by mediating the expression of SIM/SMR1 genes.

• Publication year

  2019

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2019-10-20

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.bbrc.2019.08.088PMID 31445703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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