The surface structure seen on gonococci after treatment with CMP-NANA is due to sialylation of surface lipopolysaccharide previously described as a 'capsule'.

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Microbial Pathogenesis

• Publication date

  1991-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0882-4010(91)90050-KPMID 1724790
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A surface polysaccharide forms when gonococci are converted to serum resistance by cytidine 5'-monophospho-N-acetyl neuraminic acid.

  1990cited by this paper
• In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation

  1990cited by this paper
• Resistance to human serum of gonococci in urethral exudates is reduced by neuraminidase

  1990cited by this paper
• Modification by sialic acid of Neisseria gonorrhoeae lipooligosaccharide epitope expression in human urethral exudates: an immunoelectron microscopic analysis.

  1990cited by this paper
• Sialylation of lipopolysaccharide and loss of absorption of bactericidal antibody during conversion of gonococci to serum resistance by cytidine 5'-monophospho-N-acetyl neuraminic acid.

  1989cited by this paper
• Cytidine 5'-monophospho-N-acetylneuraminic acid or a related compound is the low Mr factor from human red blood cells which induces gonococcal resistance to killing by human serum.

  1988cited by this paper
• White blood cells including polymorphonuclear phagocytes contain a factor which induces gonococcal resistance to complement‐mediated serum killing

  1988cited by this paper
• Partitioning of gonococcal LPS into phenol and water: Different LPS composition of in vivo and in vitro selected variants

  1988cited by this paper
• Antibodies to the C epitope of Neisseria gonorrhoeae are present in patients with gonorrhoea and absent in normal sera.

  1988cited by this paper
• Cytidine 5'-monophospho-N-acetyl neuraminic acid and a low molecular weight factor from human blood cells induce lipopolysaccharide alteration in gonococci when conferring resistance to killing by human serum.

  1988cited by this paper
• Gonococcal variants selected by growth in vivo or in vitro have antigenically different LPS.

  1988cited by this paper
• Lipopolysaccharide alteration is associated with induced resistance of Neisseria gonorrhoeae to killing by human serum.

  1986cited by this paper
• Definition of a virulence-related antigen of Neisseria gonorrhoeae with monoclonal antibodies and lectins.

  1986cited by this paper
• Quantitation of picomole levels of N-acetyl- and N-glycolylneuraminic acids by a HPLC-adaptation of the thiobarbituric acid assay.

  1986cited by this paper
• NZB mouse system for production of monoclonal antibodies to weak bacterial antigens: isolation of an IgG antibody to the polysaccharide capsules of Escherichia coli K1 and group B meningococci.

  1985cited by this paper
• Red blood cells, a source of factors which induce Neisseria gonorrhoeae to resistance to complement-mediated killing by human serum.

  1984cited by this paper
• Fractionation of guinea pig serum for an inducer of gonococcal resistance to killing by human serum: active fractions containing glucopeptides similar to those from human red blood cells.

  1984cited by this paper
• A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels.

  1982cited by this paper
• Electron microscopy of the gonococcal capsule.

  1981cited by this paper
• Factors affecting the induction of phenotypically determined serum resistance of Neisseria gonorrhoeae grown in media containing serum or its diffusible components.

  1981cited by this paper
• Jackal helpers and pup survival

  1979cited by this paper
• Phenotypically determined resistance of Neisseria gonorrhoeae to normal human serum: environmental factors in subcutaneous chambers in guinea pigs.

  1979cited by this paper
• Demonstration by light and electron microscopy of capsules on gonococci recently grown in vivo.

  1978cited by this paper
• The capsule of the gonococcus

  1977cited by this paper
• Production of a capsule of Neisseria gonorrhoeae

  1977cited by this paper
• Selection from gonococci grown in vitro of a colony type with some virulence properties of organisms adapted in vivo.

  1977cited by this paper
• Morphological, biological and antigenic properties of Neisseria gonorrhoeae adapted to growth in guinea-pig subcutaneous chambers.

  1976cited by this paper
• DIFFERENTIAL ABILITY OF COLONIAL TYPES OF NEISSERIA GONORRHOEAE TO PRODUCE INFECTION AND AN INFLAMMATORY RESPONSE IN SUBCUTANEOUS PERFORATED PLASTIC CHAMBERS IN GUINEA-PIGS AND RABBITS

  1975cited by this paper
• Electrophoretic resolution of the ‘major outer membrane protein’ of Escherichia coli K12 into four bands

  1975cited by this paper
• Differential ability of colonial types of Neisseria gonorrhoeae to produce infection cutaneous perforated plastic chambers in guinea-pigs and rabbits.

  1975cited by this paper
• Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action

  1971cited by this paper
• Gonococci in Urethral Exudates possess a Virulence Factor lost on Subculture

  1970cited by this paper
• PRESERVATION OF LIVING CELLS BY FREEZE‐DRYING

  1960cited by this paper

• Transmission electron microscopy protocols for capsule visualisation in pathogenic respiratory and meningeal bacteria

  2017cites this paper
• Bacteremia in an Immunocompromised Patient Caused by a Commensal Neisseria meningitidis Strain Harboring the Capsule Null Locus (cnl)

  2004cites this paper
• Interactions between Neisseria meningitidis and human cells that promote colonisation and disease

  2004cites this paper
• Host-pathogen interactions In vivo experiments with N eisseria gonorrhoeae

  2001influential citation
• Uptake of metabolites by gonococci grown with lactate in a medium containing glucose: evidence for a surface location of the sialyltransferase.

  2000cites this paper
• The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis.

  1999cites this paper
• A Novel Sialic Acid Binding Site on Factor H Mediates Serum Resistance of Sialylated Neisseria gonorrhoeae

  1998cites this paper
• Characterization of a sialyltransferase-deficient mutant of Neisseria gonorrhoeae strain F62: instability of transposon Tn1545 delta3 in gonococci and evidence that multiple genetic loci are essential for lipooligosaccharide sialylation.

  1998cites this paper
• Increase of glycocalyx and altered lectin agglutination profiles of Pasteurella haemolytica A1 after incubation in bovine subcutaneous tissue chambers in vivo or in ruminant serum in vitro

  1997cites this paper
• Sialylation lessens the infectivity of Neisseria gonorrhoeae MS11mkC.

  1996cites this paper
• A serum-sensitive, sialyltransferase-deficient mutant of Neisseria gonorrhoeae defective in conversion to serum resistance by CMP-NANA or blood cell extracts.

  1995cites this paper
• Sialylation of neisserial lipopolysaccharide: a major influence on pathogenicity.

  1995cites this paper
• Aeromonas salmonicida grown in vivo

  1993cites this paper
• Gonococci in vivo: Host CMP-NANA, sialylated lipopolysaccharide and serum resistance.

  1993cites this paper
• Some Structural Aspects of the Antigenic O-Polysaccharide Components of Salmonella Somatic Lipopolysaccharides

  1993cites this paper
• Neisseria gonorrhoeae strain MS11 harbouring a mutation in gene aroA is attenuated and immunogenic.

  1993cites this paper
• Detection and some properties of the sialyltransferase implicated in the sialylation of lipopolysaccharide of Neisseria gonorrhoeae.

  1993cites this paper
• Role of the YadA protein in prevention of opsonization of Yersinia enterocolitica by C3b molecules

  1993cites this paper
• The serum resistance of gonococci in the majority of urethral exudates is due to sialylated lipopolysaccharide seen as a surface coat

  1992cites this paper
• A high Mr factor in human blood which confers serum resistance on gonococci: some properties and synergism with CMP-NANA.

  1992cites this paper
• The sialylation of gonococcal lipopolysaccharide by host factors: a major impact on pathogenicity.

  1992cites this paper
• The serum resistance of gonococci in the majority of urethral exudates is due to sialylated lipopolysaccharide seen as a surface coat.

  1992cites this paper
• The Leeuwenhoek Lecture, 1991. The influence of the host on microbes that cause disease

  1991cites this paper