Inactivation of purified ox kidney branched‐chain 2‐oxoacid dehydrogenase complex by phosphorylation

No abstract is available for this paper.

• Publication year

  1981

• Venue

  FEBS Letters

• Publication date

  1981-09-28

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/0014-5793(81)81180-5PMID 7297698
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The regulation of branched-chain 2-oxo acid dehydrogenase of liver, kidney and heart by phosphorylation.

  1981cited by this paper
• Inactivation of rat liver and kidney branched chain 2‐oxoacid dehydrogenase complex by adenosine triphosphate

  1981cited by this paper
• Reversible ATP-induced inactivation of branched-chain 2-oxo acid dehydrogenase.

  1980cited by this paper
• Active and inactive forms of branched‐chain 2‐oxoacid dehydrogenase complex in rat heart and skeletal muscle

  1980cited by this paper
• Direct evidence for the inactivation of branched‐chain oxo‐acid dehydrogenase by enzyme phosphorylation

  1980cited by this paper
• Leucine degradation in cell-free extracts of skeletal muscle.

  1979cited by this paper
• Regulation of pig heart pyruvate dehydrogenase by phosphorylation. Studies on the subunit and phosphorylation stoicheiometries.

  1978cited by this paper
• Purification and characterization of branched chain alpha-keto acid dehydrogenase complex of bovine kidney.

  1978cited by this paper
• Inactivation of rat heart branched‐chain 2‐oxoacid dehydrogenase complex by adenosine triphosphate

  1978cited by this paper
• Regulation of heart muscle pyruvate dehydrogenase kinase.

  1974cited by this paper
• -Keto acid dehydrogenase complexes. XVI. Studies on the subunit structure of the pyruvate dehydrogenase complexes from bovine kidney and heart.

  1972cited by this paper
• α-Keto acid dehydrogenase complexes

  1972cited by this paper

• Component co-expression and purification of recombinant human pyruvate dehydrogenase complex from baculovirus infected SF9 cells.

  2014cites this paper
• Modified method for purifying rat liver branched-chain alpha-ketoacid dehydrogenase complex.

  2009cites this paper
• Modified Method for Purifying Rat Liver Branched-Chain α-Ketoacid Dehydrogenase Complex

  2009cites this paper
• Chapter 8 - Fifty Years of Biochemistry as Enjoyed by a Medical Biochemist Motivated by an Interest in Diabetes

  2003cites this paper
• Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats.

  2002cites this paper
• Uteroplacental Insufficiency Alters Liver and Skeletal Muscle Branched-Chain Amino Acid Metabolism in Intrauterine Growth-Restricted Fetal Rats

  2001cites this paper
• Branched-chain alpha-keto acid dehydrogenase kinase.

  2000cites this paper
• Branched-chain alpha-keto acid dehydrogenase kinase.

  2000cites this paper
• Regulation of branched-chain amino acid metabolism in the lactating rat.

  1998cites this paper
• Stimulation of rat-liver branched-chain alpha-keto acid dehydrogenase activity by chronic metabolic acidosis.

  1998cites this paper
• Molecular cloning of the p45 subunit of pyruvate dehydrogenase kinase.

  1994cites this paper
• Effects of diabetes on the activity and content of the branched-chain alpha-ketoacid dehydrogenase complex in liver.

  1993cites this paper
• Purification and characterization of the branched chain alpha-ketoacid dehydrogenase complex from Saccharomyces cerevisiae.

  1993cites this paper
• Purification and comparative study of the kinases specific for branched chain alpha-ketoacid dehydrogenase and pyruvate dehydrogenase.

  1991cites this paper
• Purification and properties of branched-chain alpha-keto acid dehydrogenase kinase from bovine kidney.

  1991cites this paper
• Both induction and activation of the branched-chain 2-oxo acid dehydrogenase complex in primary-cultured rat hepatocytes by clofibrate.

  1991cites this paper
• Branched-chain 2-oxoacid dehydrogenase kinase activity is regulated by alteration of protein thiol groups.

  1991cites this paper
• Evidence that rat liver pyruvate dehydrogenase kinase activator protein is a pyruvate dehydrogenase kinase.

  1991cites this paper
• Immunochemical identification of branched‐chain 2‐oxo acid dehydrogenase kinase

  1991cites this paper
• Protein phosphorylation in rat liver mitochondria

  1990cites this paper
• Activation of branched-chain alpha-keto acid dehydrogenase complex by exercise: effect of high-fat diet intake.

  1990cites this paper
• Inhibition of the bovine branched-chain 2-oxo acid dehydrogenase complex and its kinase by arylidenepyruvates.

  1990cites this paper
• Purification and partial characterization of branched-chain alpha-ketoacid dehydrogenase kinase from rat liver and rat heart.

  1990cites this paper
• Regulation of the branched-chain alpha-ketoacid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease.

  1990cites this paper
• Assignment of the gene for the E1 alpha subunit of branched chain alpha-ketoacid dehydrogenase to chromosome 19.

  1989cites this paper
• cDNA cloning of the E1 alpha subunit of the branched-chain alpha-keto acid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease.

  1989cites this paper
• cDNA Cloning of the E1α Subunit of the Branshed‐Chain α‐Keto Acid Dehydrogenase and Elucidation of a Molecular Basis for Maple Syrup Urine Disease a

  1989cites this paper
• Evidence for both a regulatory mutation and a structural mutation in a family with maple syrup urine disease.

  1989cites this paper
• Longer-term regulation of branched-chain-2-oxoacid dehydrogenase complex studied in rat hepatocytes in culture.

  1989cites this paper
• Purification, resolution, and reconstitution of branched-chain 2-keto acid dehydrogenase complex from bovine kidney.

  1988cites this paper
• [21] Assay of branched-chain α-keto acid dehydrogenase kinase in mitochondrial extracts and purified branched-chain α-keto acid dehydrogenase complexes

  1988cites this paper
• Branched-chain alpha-keto acid dehydrogenase phosphatase and its inhibitor protein from bovine kidney.

  1988cites this paper
• [15] Inhibition of branched-chain α-keto acid dehyrogenase kinase by α-chloroisocaproate

  1988cites this paper
• Assay of branched-chain alpha-keto acid dehydrogenase kinase in mitochondrial extracts and purified branched-chain alpha-keto acid dehydrogenase complexes.

  1988cites this paper
• Nucleotide and deduced amino acid sequence of the E1 alpha subunit of human liver branched-chain alpha-ketoacid dehydrogenase.

  1988cites this paper
• Activity of branched-chain 2-oxo acid dehydrogenase complex in rat liver mitochondria and in rat liver.

  1988cites this paper
• Inhibition of branched-chain alpha-keto acid dehydrogenase kinase by alpha-chloroisocaproate.

  1988cites this paper
• Branched-chain alpha-keto acid dehydrogenase phosphatase and its inhibitor protein from bovine kidney.

  1988cites this paper
• Monovalent cations and inorganic phosphate alter branched-chain alpha-ketoacid dehydrogenase-kinase activity and inhibitor sensitivity.

  1988cites this paper
• Transamination and oxidation of leucine and valine in rat adipose tissue.

  1988cites this paper
• Purification of branched chain alpha-ketoacid dehydrogenase complex from rat liver.

  1987cites this paper
• Activation of branched-chain α-ketoacid dehydrogenase in isolated hepatocytes by branched-chain α-ketoacids☆

  1987cites this paper
• Purification of branched chain α-ketoacid dehydrogenase complex from rat liver☆

  1987cites this paper
• Molecular cloning of a cDNA for the E1 alpha subunit of rat liver branched chain alpha-ketoacid dehydrogenase.

  1987cites this paper
• 3 Pyruvate Dehydrogenase

  1987cites this paper
• Activation of branched-chain alpha-ketoacid dehydrogenase in isolated hepatocytes by branched-chain alpha-ketoacids.

  1987cites this paper
• Protein serine/threonine kinases.

  1987cites this paper
• 4 Branched-Chain Ketoacid Dehydrogenase

  1987cites this paper
• Regulation of the branched-chain 2-oxo acid dehydrogenase complex in hepatocytes isolated from rats fed on a low-protein diet.

  1986cites this paper
• Regulation of branched-chain alpha-ketoacid dehydrogenase complex by covalent modification.

  1986cites this paper
• Regulation of oxidative decarboxylation of branched-chain 2-oxo acids in rat liver mitochondria.

  1986cites this paper
• Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart.

  1986cites this paper
• Phosphorylation of branched-chain 2-oxo acid dehydrogenase complex in isolated adipocytes. Effects of 2-oxo acids.

  1986cites this paper
• Phosphorylation sites and inactivation of branched-chain alpha-ketoacid dehydrogenase isolated from rat heart, bovine kidney, and rabbit liver, kidney, heart, brain, and skeletal muscle.

  1986cites this paper
• Resolution of branched-chain oxo acid dehydrogenase complex of Pseudomonas aeruginosa PAO.

  1986cites this paper
• A potent, heat-stable protein inhibitor of [branched-chain alpha-keto acid dehydrogenase]-phosphatase from bovine kidney mitochondria.

  1986cites this paper
• Rat tissue concentrations of branched-chain 2-oxo acid dehydrogenase complex. Re-evaluation by immunoassay and bioassay.

  1986cites this paper
• Activation of hepatic branched-chain 2-oxoacid dehydrogenase by rat liver cytosolic supernatant.

  1986cites this paper
• Regulation of branched-chain α-ketoacid dehydrogenase complex by covalent modification

  1986cites this paper
• Regulation of branched-chain amino acid metabolism.

  1986cites this paper
• Physiological covalent regulation of rat liver branched-chain alpha-ketoacid dehydrogenase.

  1985cites this paper
• Regulation of mammalian pyruvate and branched-chain alpha-keto acid dehydrogenase complexes by phosphorylation-dephosphorylation.

  1985cites this paper
• Regulation of branched chain alpha-ketoacid dehydrogenase complex by phosphorylation-dephosphorylation. Minisymposium report.

  1985cites this paper
• Pyruvate dehydrogenase kinase activity of pig heart pyruvate dehydrogenase (E1 component of pyruvate dehydrogenase complex).

  1985cites this paper
• Resolution and reconstitution of bovine kidney branched-chain 2-oxo acid dehydrogenase complex.

  1985cites this paper
• Physiological covalent regulation of rat liver branched-chain α-ketoacid dehydrogenase

  1985cites this paper
• Purification and properties of a protein activator of phosphorylated branched-chain 2-oxo acid dehydrogenase complex.

  1985cites this paper
• Regulation of bovine kidney branched-chain 2-oxoacid dehydrogenase complex by reversible phosphorylation.

  1984cites this paper
• Clofibric acid, phenylpyruvate, and dichloroacetate inhibition of branched-chain alpha-ketoacid dehydrogenase kinase in vitro and in perfused rat heart.

  1984cites this paper
• Evidence that the mitochondrial activator of phosphorylated branched‐chain 2‐oxoacid dehydrogenase complex is the dissociated E1 component of the complex

  1984cites this paper
• Regulation of branched-chain alpha-ketoacid dehydrogenase kinase.

  1984cites this paper
• Purification and properties of branched-chain alpha-keto acid dehydrogenase phosphatase from bovine kidney.

  1984cites this paper
• Catalytic and structural properties of the dihydrolipoyl transacylase component of bovine branched-chain alpha-keto acid dehydrogenase.

  1984cites this paper
• Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues.

  1984cites this paper
• Regulatory effects of fatty acids on decarboxylation of leucine and 4-methyl-2-oxopentanoate in the perfused rat heart.

  1984cites this paper
• Multi‐site phosphorylation of bovine kidney branched‐chain 2‐oxoacid dehydrogenase complex

  1983cites this paper
• Amino acid sequence at the major phosphorylation site on bovine kidney branched‐chain 2‐oxoacid dehydrogenase complex

  1983cites this paper
• Activity state of the branched chain alpha-ketoacid dehydrogenase complex in heart, liver, and kidney of normal, fasted, diabetic, and protein-starved rats.

  1983cites this paper
• Mitochondrial 2-oxoacid dehydrogenase complexes of animal tissues.

  1983cites this paper
• Multi‐site phosphorylation of branched‐chain 2‐oxoacid dehydrogenase complex within mitochondria isolated from rat liver, kidney and heart

  1983cites this paper
• Branched-chain ketoacid dehydrogenase activity and growth of normal and mutant human fibroblasts: The effect of branched-chain amino acid concentration in culture medium

  1983cites this paper
• Rapid purification of bovine kidney branched‐chain 2‐oxoacid dehydrogenase complex containing endogenous kinase activity

  1983cites this paper
• Multi‐site phosphorylation in ox‐kidney branched‐chain 2‐oxoacid dehydrogenase complex

  1983cites this paper
• Dephosphorylation and reactivation of phosphorylated purified ox‐kidney branched‐chain dehydrogenase complex by co‐purified phosphatase

  1983cites this paper
• Evidence for the regulation of the branched chain alpha-keto acid dehydrogenase multienzyme complex by a phosphorylation/dephosphorylation mechanism.

  1982cites this paper
• Activation of phosphorylated branched chain 2‐oxoacid dehydrogenase complex

  1982cites this paper
• Regulation of the branched chain 2‐oxoacid dehydrogenase kinase reaction

  1982cites this paper
• Regulation of the branched chain alpha-keto acid and pyruvate dehydrogenases in the perfused rat heart.

  1982cites this paper
• Isolation of rabbit liver branched chain alpha-ketoacid dehydrogenase and regulation by phosphorylation.

  1982cites this paper
• Pyruvate dehydrogenase kinase/activator in rat heart mitochondria, Assay, effect of starvation, and effect of protein-synthesis inhibitors of starvation.

  1982cites this paper