Considering the complexity of neuronal circuits and their epilepsy‐associated alterations, epilepsy models cannot be completely replaced by in vitro experimental approaches. Decisions about ethical approval of in vivo studies require a thorough weighing of the animal's burden and the benefit regarding the expected gain in knowledge.
Toward evidence‐based severity assessment in rat models with repeated seizures: II. Chemical post–status epilepticus model
Ines Koska,R. M. van Dijk,Isabel Seiffert,Valentina Di Liberto,Christina Möller,R. Palme,R. Hellweg,H. Potschka
Published 2019 in Epilepsia
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
Epilepsia
- Publication date
2019-08-31
- Fields of study
Medicine, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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