Influence of fructose on the mechanisms for ethanol-induced hypertriglyceridaemia

I. Onyesom

Published 2005 in Tanzania Journal of Science

ABSTRACT

Twelve adult albino rabbits with an average weight of 1.42kg were purchased and divided equally into the normal saline, ethanol and ethanol+fructose-treated groups. The ethanol-treated group orally received 1.5g (40%) ethanol/kg body weight as single daily dose, while the ethanol +fructose-treated animals also received the same ethanol dose, but were given in addition, 0.25gfructose/kg body weight after about 10 min of the ethanol administration. The normal saline-treated rabbits were given the equivalent amount of normal saline in lieu of ethanol. The animals were exposed to these various treatments along with their usual feeding pattern for a regular period of 15 weeks. Results showed that the progressive increase (P 0.05) but decreased (P Tanzania Journal of Science Vol. 31 (2) 2005: pp. 5-12

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