Energetics of Blood Flow in Fontan Circulation under VAD Support.

The need to simulate the normal operating conditions of the human body is the key factor in every study and engineering process of bioelectronic devices designed for the implantation. The Fontan procedure is an example of such process aimed to support the human body functioning. It is a standard treatment method for patients with a functional univentricular heart. However, it has significant drawbacks such as overload of the only functional heart ventricle that often leads to the necessity of the heart transplantation. In this study we analyze the total cavopulmonary connection (TCPC) influence on the blood with and without connected auxiliary blood circulation pump. We investigate four different types of TCPC configurations, analyze blood pressure and different flow rate, study the turbulent kinetic energy distribution, and evaluate hydraulic and power losses for various cases. Finally, we calculate volumetric scalar shear stresses distribution, and demonstrate the high potential of TCPC configuration with connected rotary pump as a tool for the load redistribution in the functional heart ventricle. This work is particularly relevant for improving of existing TCPCs quality that can extend life of Fontan patients. Moreover, reduce morbidity and mortality of the patients waiting for the heart transplantation. This article is protected by copyright. All rights reserved.

• Publication year

  2019

• Venue

  Artificial Organs

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1111/aor.13564PMID 31489642
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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