Eyeless collaborates with Hedgehog and Decapentaplegic signaling in Drosophila eye induction.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Developmental Biology

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0012-1606(02)00123-9PMID 12654291
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The TGFp Homolog dpp and the Segment Polarity Gene hedgehog Are Required for Propagation of a Morphogenetic Wave in the Drosophila Retina

  2003cited by this paper
• A positive role for patched-smoothened signaling in promoting cell proliferation during normal head development in Drosophila.

  2002cited by this paper
• Hedgehog signal transduction: recent findings.

  2002cited by this paper
• Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless.

  2002cited by this paper
• Temporal control of glial cell migration in the Drosophila eye requires gilgamesh, hedgehog, and eye specification genes.

  2002cited by this paper
• An absolute requirement for Cubitus interruptus in Hedgehog signaling.

  2001cited by this paper
• Hedgehog signaling in animal development: paradigms and principles.

  2001cited by this paper
• Dpp and Hh signaling in the Drosophila embryonic eye field.

  2001cited by this paper
• Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus.

  2000influential reference
• Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila.

  2000cited by this paper
• Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein.

  2000cited by this paper
• Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system.

  2000cited by this paper
• Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus.

  2000cited by this paper
• Morphogenetic furrow initiation and progression during eye development in Drosophila: the roles of decapentaplegic, hedgehog and eyes absent.

  2000influential reference
• Early retinal development in Drosophila.

  2000cited by this paper
• Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened.

  2000cited by this paper
• Transducing the Dpp morphogen gradient in the wing of Drosophila: regulation of Dpp targets by brinker.

  1999cited by this paper
• The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation.

  1999influential reference
• Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.

  1999influential reference
• twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development.

  1999influential reference
• Ci: a complex transducer of the hedgehog signal.

  1999cited by this paper
• Progression of the morphogenetic furrow in the Drosophila eye: the roles of Hedgehog, Decapentaplegic and the Raf pathway.

  1999cited by this paper
• Dual role for Hedgehog in the regulation of the proneural gene atonal during ommatidia development.

  1999cited by this paper
• Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila.

  1999influential reference
• Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development.

  1998influential reference
• Transducing Hedgehog: the story so far

  1998cited by this paper
• The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila.

  1998influential reference
• Eye development: governed by a dictator or a junta?

  1997cited by this paper
• The eye-specification proteins So and Eya form a complex and regulate multiple steps in Drosophila eye development.

  1997cited by this paper
• The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells.

  1997influential reference
• Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye.

  1997cited by this paper
• Eye Development : Minireview Governed by a Dictator or a Junta ?

  1997cited by this paper
• The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates.

  1997cited by this paper
• Role of decapentaplegic in initiation and progression of the morphogenetic furrow in the developing Drosophila retina.

  1997cited by this paper
• A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing.

  1997cited by this paper
• Ectopic eye development in Drosophila induced by directed dachshund expression.

  1997influential reference
• Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila.

  1997cited by this paper
• Induction of Drosophila eye development by decapentaplegic.

  1997influential reference
• Retinal morphogenesis in Drosophila: hints from an eye-specific decapentaplegic allele.

  1997cited by this paper
• Hedgehog is an indirect regulator of morphogenetic furrow progression in the Drosophila eye disc.

  1997cited by this paper
• Sending and Receiving the Hedgehog Signal: Control by the Drosophila Gli Protein Cubitus interruptus

  1996cited by this paper
• Direct and long-range action of a DPP morphogen gradient.

  1996cited by this paper
• The regulation of hedgehog and decapentaplegic during Drosophila eye imaginal disc development.

  1996cited by this paper
• Hedgehog-dependent patterning in the Drosophila eye can occur in the absence of Dpp signaling.

  1996cited by this paper
• Hedgehog, transmitted along retinal axons, triggers neurogenesis in the developing visual centers of the Drosophila brain.

  1996influential reference
• Visualization of Gene Expression in Living Adult Drosophila

  1996influential reference
• Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye.

  1996cited by this paper
• Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila.

  1995influential reference
• Wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye.

  1995influential reference
• Mutations that alter the timing and pattern of cubitus interruptus gene expression in Drosophila melanogaster.

  1995cited by this paper
• Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A

  1995cited by this paper
• The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

  1995cited by this paper
• cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs.

  1995influential reference
• wingless inhibits morphogenetic furrow movement in the Drosophila eye disc.

  1995cited by this paper
• The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways.

  1995influential reference
• Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs.

  1994influential reference
• Ectopic decapentaplegic in the Drosophila midgut alters the expression of five homeotic genes, dpp, and wingless, causing specific morphological defects.

  1994cited by this paper
• Autoproteolysis in hedgehog protein biogenesis.

  1994cited by this paper
• The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system.

  1994influential reference
• Three distinct roles for the engrailed gene in Drosophila wing development.

  1994influential reference
• dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila.

  1994cited by this paper
• Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans.

  1994cited by this paper
• The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye.

  1993cited by this paper
• Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

  1993influential reference
• Organizing activity of wingless protein in Drosophila.

  1993cited by this paper
• Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.

  1992influential reference
• The Genome of Drosophila Melanogaster

  1992cited by this paper
• The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic wave.

  1991cited by this paper
• An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila.

  1991influential reference
• The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs.

  1990cited by this paper
• The engrailed locus of Drosophila: in situ localization of transcripts reveals compartment-specific expression.

  1985cited by this paper

• The Retinal Determination Gene Network in Drosophila

  2026cites this paper
• miR-137 targets Myc to regulate growth during eye development

  2025cites this paper
• Interlocking of co-opted developmental gene networks in Drosophila and the evolution of pre-adaptive novelty

  2023cites this paper
• The timing of cell fate decisions is crucial for initiating pattern formation in the Drosophila eye.

  2022cites this paper
• The early history of the eye-antennal disc of Drosophila melanogaster.

  2022cites this paper
• Yorkie-Cactus (IκBα)-JNK axis promotes tumor growth and progression in Drosophila

  2021cites this paper
• Newt regeneration genes regulate Wingless signaling to restore patterning in Drosophila eye

  2021cites this paper
• Early Eye Development: Specification and Determination

  2020cites this paper
• Catching the Next Wave: Patterning of the Drosophila Eye by the Morphogenetic Furrow

  2020cites this paper
• Hippo signaling: bridging the gap between cancer and neurodegenerative disorders

  2020cites this paper
• An E3 ubiquitin ligase, cullin‐4 regulates retinal differentiation in Drosophila eye

  2020cites this paper
• THE YKI-CACTUS (IKBα)-JNK AXIS PROMOTES TUMOR GROWTH AND PROGRESSION IN DROSOPHILA

  2020cites this paper
• Myogenesis control by SIX transcriptional complexes.

  2020cites this paper
• Drosophila Eye as a Model to Study Regulation of Growth Control: The Discovery of Size Control Pathways

  2020cites this paper
• Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye

  2020cites this paper
• A Two-Clone Approach to Study Signaling Interactions among Neuronal Cells in a Pre-clinical Alzheimer's Disease Model

  2020cites this paper
• Proximal fate marker homothorax marks the lateral extension of stalk‐eyed fly Cyrtodopsis whitei

  2019cites this paper
• Eyeless/Pax6 initiates eye formation non-autonomously from the peripodial epithelium

  2018cites this paper
• A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye

  2018cites this paper
• Pleiotropy in Drosophila organogenesis: Mechanistic insights from Combgap and the retinal determination gene network

  2018cites this paper
• Characterization of a morphogenetic furrow specific Gal4 driver in the developing Drosophila eye

  2018cites this paper
• Integrative genomic analysis reveals novel regulatory mechanisms of eyeless during Drosophila eye development

  2018cites this paper
• Master regulators in development: Views from the Drosophila retinal determination and mammalian pluripotency gene networks.

  2017influential citation
• Noncanonical Decapentaplegic Signaling Activates Matrix Metalloproteinase 1 To Restrict Hedgehog Activity and Limit Ectopic Eye Differentiation in Drosophila

  2017cites this paper
• Dynamic genome wide expression profiling of Drosophila head development reveals a novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

  2017cites this paper
• Expression profiling reveals novel role of Hunchback in retinal glia cell development and blood-brain barrier integrity

  2017cites this paper
• Identification of Novel Direct Targets of Drosophila Sine Oculis by Integration of Genome-wide Data Sets

  2016cites this paper
• Identification of novel direct targets of Drosophila Sine oculis and Eyes absent by integration of genome-wide data sets.

  2016cites this paper
• The morphogen Decapentaplegic employs a two-tier mechanism to activate target retinal determining genes during ectopic eye formation in Drosophila

  2016cites this paper
• Role of Growth Regulatory Pathways in Eye Development and Differentiation

  2014cites this paper
• Hipk promotes photoreceptor differentiation through the repression of Twin of eyeless and Eyeless expression.

  2014cites this paper
• Catching the Next Wave: Patterning of the Drosophila Eye by the Morphogenetic Furrow

  2013cites this paper
• Retinal differentiation in Drosophila

  2013cites this paper
• Segregation of eye and antenna fates maintained by mutual antagonism in Drosophila

  2012cites this paper
• MAPK Target Sites of Eyes Absent Are Not Required for Eye Development or Survival in Drosophila

  2012cites this paper
• The protein kinase Nemo integrates specification, proliferation and morphogenesis to shape the Drosophila eye

  2011cites this paper
• The eye imaginal disc as a model to study the coordination of neuronal and glial development

  2010cites this paper
• Identification of Retinal Transformation Hot Spots in Developing Drosophila Epithelia

  2010influential citation
• Dorsal eye selector pannier (pnr) suppresses the eye fate to define dorsal margin of the Drosophila eye.

  2010cites this paper
• Retinal determination the beginning of eye development.

  2010cites this paper
• The transcriptional co-factor Chip acts with LIM-homeodomain proteins to set the boundary of the eye field in Drosophila

  2010cites this paper
• Braid and Verheyen Nemo promotes eye specification 1 Drosophila Nemo Promotes Eye Specification Directed by the Retinal Determination Gene Network

  2008cites this paper
• Drosophila Nemo Promotes Eye Specification Directed by the Retinal Determination Gene Network

  2008cites this paper
• Ancient mechanisms of visual sense organ development based on comparison of the gene networks controlling larval eye, ocellus, and compound eye specification in Drosophila.

  2006cites this paper
• Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog

  2005cites this paper
• Duplicated Pax6 genes in Glomeris marginata (Myriapoda: Diplopoda), an arthropod with simple lateral eyes.

  2005cites this paper
• Developmental palaeobiology of trilobite eyes and its evolutionary significance

  2005cites this paper
• Conservation and non-conservation of genetic pathways in eye specification.

  2004cites this paper
• Coming to our senses.

  2004cites this paper
• Molecular genetic analysis of a "sine oculis" enhancer and the "leventina" gene as a model system to study human macular degeneration in "Drosophila"

  2004cites this paper
• Genetic analysis of genes found on the 4th chromosome of Drosophila - emphasizing the developmental context of Pax6

  2004cites this paper
• The Eye Specification Network in Drosophila.

  2004cites this paper
• The Epistemology of Development, Evolution, and Genetics: DEVELOPMENT

  2004cites this paper
• The Epistemology of Development, Evolution, and Genetics: On Conflicts between Genetic and Developmental Viewpoints – and Their Attempted Resolution in Molecular Biology

  2004cites this paper
• Stem cells and retinal repair.

  2004cites this paper
• Reconceiving Animals and Their Evolution: On Some Consequences of New Research on the Modularity of Development and Evolution

  2004cites this paper
• Transdetermination in Drosophila imaginal discs: a model for understanding pluripotency and selector gene maintenance.

  2003cites this paper
• Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development

  2003cites this paper
• Drosophila Nemo Promotes Eye Specification Directed by the Retinal Determination Gene Network

  year unknowncites this paper