Oscillating Purkinje neuron activity causing involuntary eye movement in a mutant mouse deficient in the glutamate receptor delta2 subunit.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Neuroscience

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15014119PMCID PMC6729495
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Locomotor deficits in the mutant mouse, Lurcher

  2004cited by this paper
• Distal Extension of Climbing Fiber Territory and Multiple Innervation Caused by Aberrant Wiring to Adjacent Spiny Branchlets in Cerebellar Purkinje Cells Lacking Glutamate Receptor δ2

  2002influential reference
• Expression of Protein Kinase C Inhibitor Blocks Cerebellar Long-Term Depression without Affecting Purkinje Cell Excitability in Alert Mice

  2001influential reference
• Roles of Glutamate Receptor δ2 Subunit (GluRδ2) and Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Climbing Fiber Synapse Elimination during Postnatal Cerebellar Development

  2001influential reference
• Motor skills and motor learning in Lurcher mutant mice during aging.

  2001cited by this paper
• Dynamic properties, interactions and adaptive modifications of vestibulo-ocular reflex and optokinetic response in mice.

  2001cited by this paper
• Beyond parallel fiber LTD: the diversity of synaptic and non-synaptic plasticity in the cerebellum

  2001cited by this paper
• Classical eyeblink conditioning in glutamate receptor subunit δ2 mutant mice is impaired in the delay paradigm but not in the trace paradigm

  2001cited by this paper
• Cerebellar long-term depression: characterization, signal transduction, and functional roles.

  2001cited by this paper
• Mutant mice as a model for cerebellar ataxia.

  2001cited by this paper
• Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons

  2000cited by this paper
• Inhibition of nitric oxide synthesis and gene knockout of neuronal nitric oxide synthase impaired adaptation of mouse optokinetic response eye movements.

  2000cited by this paper
• Mutation of a glutamate receptor motif reveals its role in gating and δ2 receptor channel properties

  2000cited by this paper
• A comparison of video and magnetic search coil recordings of mouse eye movements.

  2000cited by this paper
• Suppression of inhibitory synaptic potentiation by presynaptic activity through postsynaptic GABA(B) receptors in a Purkinje neuron.

  2000cited by this paper
• Long-term depression of the cerebellar climbing fiber--Purkinje neuron synapse.

  2000cited by this paper
• Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin.

  1999influential reference
• Patterns of Spontaneous Purkinje Cell Complex Spike Activity in the Awake Rat

  1999cited by this paper
• Ionic Currents Underlying Spontaneous Action Potentials in Isolated Cerebellar Purkinje Neurons

  1999cited by this paper
• Plasticity in the intrinsic excitability of cortical pyramidal neurons

  1999cited by this paper
• Evidence for NMDA and mGlu receptor-dependent long-term potentiation of mossy fiber-granule cell transmission in rat cerebellum.

  1999cited by this paper
• Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex.

  1998cited by this paper
• Impaired parallel fiber→purkinje cell synapse stabilization during cerebellar development of mutant mice lacking the glutamate receptor δ2 subunit

  1998influential reference
• Improvement in motor performance of Weaver mutant mice following lesions of the cerebellum.

  1998cited by this paper
• The tetrameric structure of a glutamate receptor channel.

  1998cited by this paper
• Impaired Parallel Fiber→Purkinje Cell Synapse Stabilization during Cerebellar Development of Mutant Mice Lacking the Glutamate Receptor δ2 Subunit

  1997cited by this paper
• Differential Roles of Apamin- and Charybdotoxin-Sensitive K+ Conductances in the Generation of Inferior Olive Rhythmicity In Vivo

  1997cited by this paper
• Neurodegeneration in Lurcher mice caused by mutation in δ2 glutamate receptor gene

  1997influential reference
• δ‐Glutamate Receptors Are Differentially Distributed at Parallel and Climbing Fiber Synapses on Purkinje Cells

  1997cited by this paper
• Analysis of spontaneous electrical activity in cerebellar Purkinje cells acutely isolated from postnatal rats.

  1997cited by this paper
• Some organizing principles for the control of movement based on olivocerebellar physiology.

  1997cited by this paper
• Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor coordination in GFAP mutant mice.

  1996cited by this paper
• Developmental changes in expression and distribution of the glutamate receptor channel delta 2 subunit according to the Purkinje cell maturation.

  1996cited by this paper
• Suppression of the glutamate receptor delta 2 subunit produces a specific impairment in cerebellar long-term depression.

  1996influential reference
• The Cerebellum: A Neuronal Learning Machine?

  1996cited by this paper
• Postsynaptic mechanisms underlying long-term depression of GABAergic transmission in neurons of the deep cerebellar nuclei.

  1996cited by this paper
• Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice.

  1995cited by this paper
• Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice

  1995cited by this paper
• Dynamic organization of motor control within the olivocerebellar system

  1995cited by this paper
• Retarded vestibular compensation in mutant mice deficient in delta 2 glutamate receptor subunit.

  1995cited by this paper
• Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit.

  1995cited by this paper
• Long-term synaptic depression.

  1995cited by this paper
• Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor δ2 subunit

  1995influential reference
• Retarded vestibular compensation in mutant mice deficient in δ2 glutamate receptor subunit

  1995cited by this paper
• Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice.

  1995cited by this paper
• Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluRδ2 mutant mice

  1995influential reference
• Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

  1994cited by this paper
• Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice.

  1994cited by this paper
• Involvement of the glutamate receptor δ2 subunit in the long-term depression of glutamate responsiveness in cultured rat Purkinje cells

  1994influential reference
• Cloned glutamate receptors.

  1994cited by this paper
• Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

  1994cited by this paper
• Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells.

  1993cited by this paper
• The rat delta‐1 and delta‐2 subunits extend the excitatory amino acid receptor family

  1993cited by this paper
• Selective Expression of the Glutamate Receptor Channel δ2 Subunit in Cerebellar Purkinje Cells

  1993cited by this paper
• Cerebellectomy eliminates the motor syndrome of the genetically dystonic rat.

  1993cited by this paper
• Synaptic excitation produces a long-lasting rebound potentiation of inhibitory synaptic signals in cerebellar Purkinje cells

  1992cited by this paper
• Synaptic currents in cerebellar Purkinje cells.

  1990cited by this paper
• Oscillatory properties of guinea‐pig inferior olivary neurones and their pharmacological modulation: an in vitro study.

  1986cited by this paper
• The cerebellum and neural control

  1984cited by this paper
• Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices.

  1980cited by this paper
• Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices.

  1980cited by this paper
• Control of eye movement

  1978cited by this paper
• Cerebellar histogenesis in the lurcher (Lc) mutant mouse

  1977cited by this paper

• Autoimmune Cerebellar Ataxia Associated with Anti-Glutamate Receptor δ2 Antibodies: a Rare but Treatable Entity

  2023cites this paper
• Is essential tremor a disorder of GABA dysfunction? No.

  2022cites this paper
• Acute Cerebellar Inflammation and Related Ataxia: Mechanisms and Pathophysiology

  2022cites this paper
• Increased Climbing Fiber Lateral Crossings on Purkinje Cell Dendrites in the Cerebellar Hemisphere in Essential Tremor

  2021influential citation
• Synergistic excitability plasticity in cerebellar functioning

  2020cites this paper
• Essential Tremor - a cerebellar driven disorder?

  2020cites this paper
• Glutamate receptor δ2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome

  2018cites this paper
• NMDA receptors play important roles in acquisition and expression of the eyeblink conditioned response in glutamate receptor subunit 2 mutant mice

  2018cites this paper
• Animal Models of Tremor: Relevance to Human Tremor Disorders

  2018cites this paper
• A GABAergic Dysfunction in the Olivary–Cerebellar–Brainstem Network May Cause Eye Oscillations and Body Tremor. II. Model Simulations of Saccadic Eye Oscillations

  2017cites this paper
• The Successful Application of Plasmapheresis in the Treatment of a Patient with Opsoclonus and Autoantibodies to Glutamate Receptor δ2

  2017cites this paper
• Climbing fiber-Purkinje cell synaptic pathology in tremor and cerebellar degenerative diseases

  2016cites this paper
• Title Long-term Potentiation of Inhibitory Synaptic Transmission onto Cerebellar Purkinje Neurons Contributes to Adaptation of Vestibulo-Ocular Reflex

  2016cites this paper
• Purkinje cell responses during visually and vestibularly driven smooth eye movements in mice

  2015cites this paper
• Opsoclonus associated with autoantibodies to glutamate receptors δ2

  2015cites this paper
• Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum.

  2015cites this paper
• Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice

  2015cites this paper
• A unifying neurologic mechanism for infantile nystagmus.

  2014cites this paper
• Altered Actions of Memantine and NMDA-Induced Currents in a New Grid2-Deleted Mouse Line

  2014cites this paper
• Abnormal climbing fibre-Purkinje cell synaptic connections in the essential tremor cerebellum.

  2014cites this paper
• Deletions in GRID2 lead to a recessive syndrome of cerebellar ataxia and tonic upgaze in humans

  2013cites this paper
• Long-term Potentiation of Inhibitory Synaptic Transmission onto Cerebellar Purkinje Neurons Contributes to Adaptation of Vestibulo-Ocular Reflex

  2013cites this paper
• Disruption of cerebellar microzonal organization in GluD2 (GluRδ2) knockout mouse

  2013cites this paper
• Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners

  2012cites this paper
• Opsoclonus: clinical and immunological features.

  2012cites this paper
• Computational Modelling of Information Processing in Deep Cerebellar Nucleus Neurons

  2012cites this paper
• Glutamate Receptor δ2 Is Essential for Input Pathway-Dependent Regulation of Synaptic AMPAR Contents in Cerebellar Purkinje Cells

  2011cites this paper
• Involvement of the Cerebellar Synaptic Plasticity in Adaptation of the Vestibulo-Ocular Reflex and Optokinetic Response

  2011cites this paper
• Cognitive repercussions of hereditary cerebellar disorders.

  2011cites this paper
• Glutamate-Receptor-Like Molecule GluRδ2 Involved in Synapse Formation at Parallel Fiber-Purkinje Neuron Synapses

  2010cites this paper
• Ablation of Glutamate Receptor GluRδ2 in Adult Purkinje Cells Causes Multiple Innervation of Climbing Fibers by Inducing Aberrant Invasion to Parallel Fiber Innervation Territory

  2010cites this paper
• To Gate or not to Gate: Are the Delta Subunits in the Glutamate Receptor Family Functional Ion Channels?

  2008cites this paper
• Inferior olive hypertrophy and cerebellar learning are both needed to explain ocular oscillations in oculopalatal tremor.

  2008cites this paper
• Asymmetric recovery in cerebellar-deficient mice following unilateral labyrinthectomy.

  2008influential citation
• Motor control mechanism by the cerebellum

  2008cites this paper
• Bifurcation theory explains waveform variability in a congenital eye movement disorder

  2008cites this paper
• Increased occurrence of climbing fiber inputs to the cerebellar flocculus in a mutant mouse is correlated with the timing delay of optokinetic response

  2007cites this paper
• The Lurcher mouse: fresh insights from an old mutant.

  2007cites this paper
• Sparse cerebellar innervation can morph the dynamics of a model oculomotor neural integrator

  2007cites this paper
• Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol.

  2007cites this paper
• Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission

  2007cites this paper
• Neural mechanism underlying the transsynaptic shift of memory trace in motor learning

  2006cites this paper
• Integrin alpha3beta1 suppresses long-term potentiation at inhibitory synapses on the cerebellar Purkinje neuron.

  2006cites this paper
• Cerebellar regulation mechanisms learned from studies on GluRdelta2.

  2006cites this paper
• Response to Gilbert: Rhythmicity, randomness and synchrony in climbing fiber signals

  2006cites this paper
• Integrin α3β1 suppresses long-term potentiation at inhibitory synapses on the cerebellar Purkinje neuron

  2006cites this paper
• Mechanism of cerebellar function studied using mutant mice

  2006cites this paper
• Antiphasic Purkinje cell responses in mouse uvula-nodulus are sensitive to static roll-tilt and topographically organized.

  2006cites this paper
• Cerebellar regulation mechanisms learned from studies on GluRδ2

  2006cites this paper
• Impaired cerebellar functions in mutant mice lacking DNER.

  2006cites this paper
• Defective control and adaptation of reflex eye movements in mutant mice deficient in either the glutamate receptor δ2 subunit or Purkinje cells

  2005cites this paper
• N-methyl-D-aspartate receptors play important roles in acquisition and expression of the eyeblink conditioned response in glutamate receptor subunit delta2 mutant mice.

  2005cites this paper
• Rhythmicity, randomness and synchrony in climbing fiber signals.

  2005cites this paper
• —神経情報科学サマースクールNISS2002講義録— 小脳皮質のニューロン・回路と機能

  2004cites this paper
• Enhanced Inhibitory Synaptic Transmission in the Cerebellar Molecular Layer of the GluRδ2 Knock-Out Mouse

  2004influential citation
• Two reciprocal translocations provide new clues to the high mutability of the Grid2 locus

  2004cites this paper
• Edinburgh Research Explorer Ablation of Glutamate Receptor GluR delta 2 in Adult Purkinje Cells Causes Multiple Innervation of Climbing Fibers by Inducing Aberrant Invasion to Parallel Fiber Innervation Territory

  year unknowncites this paper