Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of Immunology

• Publication date

  2015-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.1402006PMID 25917084
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.

  2017cited by this paper
• Cell-Specific TLR9 Trafficking in Primary APCs of Transgenic TLR9-GFP Mice

  2013cited by this paper
• An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing

  2013cited by this paper
• Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

  2013cited by this paper
• An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing

  2013cited by this paper
• UNC93B1 mediates differential trafficking of endosomal TLRs

  2013cited by this paper
• Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

  2013cited by this paper
• Signaling organelles of the innate immune system.

  2012cited by this paper
• Designing a type I interferon signaling phagosome.

  2012cited by this paper
• Differential but Competitive Binding of Nogo Protein and Class I Major Histocompatibility Complex (MHCI) to the PIR-B Ectodomain Provides an Inhibition of Cells*

  2011cited by this paper
• Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum.

  2011cited by this paper
• Arabidopsis RTNLB1 and RTNLB2 Reticulon-Like Proteins Regulate Intracellular Trafficking and Activity of the FLS2 Immune Receptor[C][W]

  2011cited by this paper
• Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation.

  2011cited by this paper
• GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria

  2011cited by this paper
• Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation

  2010cited by this paper
• Functions of Nogo proteins and their receptors in the nervous system

  2010cited by this paper
• Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling

  2010cited by this paper
• Ras-related protein Rab10 facilitates TLR4 signaling by promoting replenishment of TLR4 onto the plasma membrane

  2010cited by this paper
• The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

  2010cited by this paper
• Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair

  2009cited by this paper
• Augmented TLR9-induced Btk activation in PIR-B–deficient B-1 cells provokes excessive autoantibody production and autoimmunity

  2009cited by this paper
• Central Nervous System Regeneration Inhibitors and their Intracellular Substrates

  2009cited by this paper
• Reticulon-4A (Nogo-A) Redistributes Protein Disulfide Isomerase to Protect Mice from SOD1-Dependent Amyotrophic Lateral Sclerosis

  2009cited by this paper
• STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

  2009cited by this paper
• Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

  2009cited by this paper
• A cell biological view of Toll-like receptor function: regulation through compartmentalization

  2009cited by this paper
• PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

  2008cited by this paper
• UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

  2008influential reference
• STING an Endoplasmic Reticulum Adaptor that Facilitates Innate Immune Signaling

  2008cited by this paper
• Reticulon RTN2B Regulates Trafficking and Function of Neuronal Glutamate Transporter EAAC1*

  2008cited by this paper
• Polar Mapper: a computational tool for integrated visualization of protein interaction networks and mRNA expression data

  2008cited by this paper
• A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

  2007cited by this paper
• Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages.

  2007cited by this paper
• The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

  2007influential reference
• Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4.

  2007cited by this paper
• Shotgun proteomics using the iTRAQ isobaric tags.

  2006cited by this paper
• The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

  2006cited by this paper
• Pathogen recognition and innate immunity.

  2006cited by this paper
• Glial inhibition of CNS axon regeneration

  2006cited by this paper
• A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53

  2005cited by this paper
• Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi.

  2005cited by this paper
• Golgins and GTPases, giving identity and structure to the Golgi apparatus.

  2005cited by this paper
• Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9.

  2004cited by this paper
• Nogo and its paRTNers.

  2003cited by this paper
• Genomic structure and functional characterisation of the promoters of human and mouse nogo/rtn4.

  2003cited by this paper
• Myelin-Associated Glycoprotein as a Functional Ligand for the Nogo-66 Receptor

  2002cited by this paper
• Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth

  2002cited by this paper
• Patterns of Nogo mRNA and Protein Expression in the Developing and Adult Rat and After CNS Lesions

  2002cited by this paper
• Myelin-associated glycoprotein interacts with the Nogo66 receptor to inhibit neurite outgrowth.

  2002cited by this paper
• Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

  2001cited by this paper
• Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion.

  2000cited by this paper
• Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein

  2000influential reference
• Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

  2000influential reference
• GRAM, a novel domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins.

  2000cited by this paper
• Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1

  1999cited by this paper
• Constitutive tyrosine phosphorylation of the inhibitory paired Ig-like receptor PIR-B.

  1999cited by this paper
• Molecular Cloning of a Novel Murine Cell-surface Glycoprotein Homologous to Killer Cell Inhibitory Receptors*

  1997cited by this paper
• A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells.

  1997cited by this paper
• Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression

  1994cited by this paper

• mimicDetector: a pipeline for protein motif mimicry detection in host-pathogen interactions

  2026cites this paper
• Nogo-B impairs efferocytosis in monocyte-derived macrophages and exacerbates septic liver injury

  2025cites this paper
• mimicDetector: a pipeline for protein motif mimicry detection in host-pathogen systems

  2025cites this paper
• The Overexpression of RTN4 Significantly Associated With an Unfavourable Prognosis in Patients With Lower‐Grade Gliomas

  2025cites this paper
• Nuclear envelope rupture in cardiomyocytes orchestrates early transcriptomic changes and immune activation in LMNA-DCM that are reversed by LINC complex disruption

  2024cites this paper
• Examining genotype-phenotype associations of GRAM domain proteins using GWAS, PheWAS and literature review in cattle, human, pig, mouse and chicken

  2024cites this paper
• Identification of Sex-Specific Genetic Polymorphisms Associated with Asthma in Middle-Aged and Older Canadian Adults: An Analysis of CLSA Data

  2023cites this paper
• IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses

  2022cites this paper
• IFITM3 regulates virus-induced inflammatory cytokine production by titrating Nogo-B orchestration of TLR responses

  2021influential citation
• Gene variations in Autism Spectrum Disorder are associated with alternation of gut microbiota, metabolites and cytokines

  2021cites this paper
• Nogo-B promotes epithelial-mesenchymal transition in lung fibrosis via PERK branch of the endoplasmic reticulum stress pathway

  2021cites this paper
• GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma

  2021cites this paper
• The myocardial infarct-exacerbating effect of cell-free DNA is mediated by the high-mobility group box 1-receptor for advanced glycation end products-Toll-like receptor 9 pathway.

  2019cites this paper
• Microglial homeostasis requires balanced CSF-1/CSF-2 receptor signaling

  2019cites this paper
• The myocardial infarct-exacerbating effect of cell-free DNA is mediated by HMGB1-RAGE-TLR9 pathway

  2019cites this paper
• Nogo‐B promotes tumor angiogenesis and provides a potential therapeutic target in hepatocellular carcinoma

  2018cites this paper
• Deciphering molecular consequences of the proprotein convertase 1/3 inhibition in macrophages for application in anti-tumour immunotherapy.

  2018cites this paper
• Nogo-B Promotes Angiogenesis in Proliferative Diabetic Retinopathy via VEGF/PI3K/Akt Pathway in an Autocrine Manner

  2017cites this paper
• Nogo-B Facilitates LPS-Mediated Immune Responses by Up-Regulation of TLR4-Signaling in Macrophage RAW264.7

  2017cites this paper
• NOGO-A/RTN4A and NOGO-B/RTN4B are simultaneously expressed in epithelial, fibroblast and neuronal cells and maintain ER morphology

  2016cites this paper
• De la classification moléculaire des gliomes à une nouvelle stratégie thérapeutique de réactivation des macrophages au sein de la tumeur

  2016cites this paper
• The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways

  2016cites this paper