Bone Mineral Density and Trabecular Bone Score in Patients with Non-Radiographic Axial Spondyloarthropathy

Background: spondyloarthropathies (SpA) are a group of chronic inflammatory rheumatic conditions that share multiple clinical features including axial and/or peripheral arthritis, enthesitis, absence of serum rheumatoid factor and presence of common extra articular manifestations. Objective: the aim of this work is to study bone mineral density and trabecular bone score at patients with nonradiographic axial spondyloarthropathy. Patients and Methods: this study is a cross sectional study in which 200 patients having chronic back pain selected from those attending the outpatient clinic and inpatient of Al-Azhar University Hospitals, Damietta and were divided into two groups: 1- (Group A, study group): (160) patients had inflammatory low back pain fulfilling Calin criteria for inflammatory low back pain. 2- (Group B, control group): (40) patients had mechanical low back pain not fulfilling criteria of inflammatory back pain. Results: regarding results of clinical examination, there was significant increase of arthritis, dactylitis, enthesitis and psoriasis in Group A when compared to Group B (43.3%, 16.7%, 30.0%, 20.0% vs 3.3%, 0.0%, 3.3% and 3.3% respectively). In addition, there was significant increase of arthritis plus dactylitis and arthritis plus enthesitis in Group A when compared to Group B (16.7%, 30.0% vs 3.3% and 0.0% respectively). Conclusion: results of the present study proved that, both bone mineral density and trabecular bone scores showed early changes in patients with non-radiographic axial spondylo-arthropathy. In addition, both correlated with each other and with results of axial magnetic resonance imaging. Thus, they are advocated in diagnosis of nr. SPA.

• Publication year

  2019

• Venue

  The Egyptian Journal of Hospital Medicine

• Publication date

  2019-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.12816/EJHM.2019.45044
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Recommendations for acquisition and interpretation of MRI of the spine and sacroiliac joints in the diagnosis of axial spondyloarthritis in the UK.

  2019influential reference
• A Fifty‐Two–Week, Randomized, Placebo‐Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis

  2019cited by this paper
• Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis

  2018influential reference
• Comparison of Patients with Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis-A Cross Sectional Study

  2018influential reference
• Impact of lumbar syndesmophyte on bone health as assessed by bone density (BMD) and bone texture (TBS) in men with axial spondyloarthritis.

  2017cited by this paper
• Serum inflammatory biomarkers fail to identify early axial spondyloarthritis: results from the SpondyloArthritis Caught Early (SPACE) cohort

  2017cited by this paper
• Trabecular Bone Score in obese, overweight and normal-weight young men

  2017influential reference
• MRI evidence of structural changes in the sacroiliac joints of patients with non-radiographic axial spondyloarthritis even in the absence of MRI inflammation

  2017cited by this paper
• Severe bone marrow edema on sacroiliac joint MRI increases the risk of low BMD in patients with axial spondyloarthritis

  2016cited by this paper
• The prevalence and clinical characteristics of nonradiographic axial spondyloarthritis among patients with inflammatory back pain in rheumatology practices: a multinational, multicenter study

  2016cited by this paper
• Nonsteroidal Antiinflammatory Drugs for Axial Spondyloarthritis: A Cochrane Review

  2016cited by this paper
• A Meta‐Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX

  2016cited by this paper
• Impact of tobacco smoking on response to tumour necrosis factor-alpha inhibitor treatment in patients with ankylosing spondylitis: results from the Danish nationwide DANBIO registry.

  2016cited by this paper
• Assessment of fracture risk in patients with axial spondyloarthritis: a case–control study using the fifth Korean National Health and Nutrition Examination Survey (KNHANES V)

  2016cited by this paper
• Spondyloarthropathies: Sacroiliac joint radiographic progression — speed and determinants

  2016influential reference
• Correlation between clinical and MRI disease activity scores in axial spondyloarthritis

  2015cited by this paper
• EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice

  2015influential reference
• Bone mass in axial spondyloarthritis: A literature review.

  2015cited by this paper
• Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score.

  2015influential reference
• FRI0232 Evaluations of Bone Microarchitectural Status of the Lumbar Spine in Ankylosing Spondylitis Patients by Trabecular Bone Score Assessment

  2015cited by this paper
• Ankylosing spondylitis confers substantially increased risk of clinical spine fractures: a nationwide case-control study

  2014influential reference
• Evidence for inflammation-induced bone loss in non-radiographic axial spondyloarthritis.

  2014cited by this paper
• Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN)

  2014cited by this paper
• The prevalence of inflammatory back pain: population-based estimates from the US National Health and Nutrition Examination Survey, 2009–10

  2012cited by this paper
• Current Concept of Spondyloarthritis: Special Emphasis on Early Referral and Diagnosis

  2012cited by this paper
• Trabecular bone score improves fracture risk prediction in non-osteoporotic women: the OFELY study

  2012cited by this paper
• Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

  2012cited by this paper
• Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis

  2011cited by this paper
• Bone loss in very early inflammatory back pain in undifferentiated spondyloarthropathy: a 1-year observational study

  2010cited by this paper
• The diagnostic utility of magnetic resonance imaging in spondylarthritis: an international multicenter evaluation of one hundred eighty-seven subjects.

  2010cited by this paper
• Spondyloarthritis: update on pathogenesis and management.

  2005cited by this paper
• Combining information obtained from magnetic resonance imaging and conventional radiographs to detect sacroiliitis in patients with recent onset inflammatory back pain

  2005cited by this paper
• The Global Burden of Disease Study

  2003cited by this paper
• Update on Spondyloarthropathies

  2002influential reference
• Clinical applications of visual analogue scales: a critical review

  1988cited by this paper

• No citing papers are available for this paper.