A Role for Intercellular Antigen Transfer in the Recognition of EBV-Transformed B Cell Lines by EBV Nuclear Antigen-Specific CD4+ T Cells1

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Immunology

• Publication date

  2006-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.177.6.3746PMID 16951335
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins

  2006cited by this paper
• CD4+ T-Cell Responses to Epstein-Barr Virus (EBV) Latent-Cycle Antigens and the Recognition of EBV-Transformed Lymphoblastoid Cell Lines

  2005cited by this paper
• Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

  2005cited by this paper
• Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens.

  2005cited by this paper
• CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells

  2005cited by this paper
• Long-Term MHC Class II Presentation of the EBV Lytic Protein BHRF1 by EBV Latently Infected B Cells following Capture of BHRF1 Antigen1

  2005cited by this paper
• Endogenous MHC Class II Processing of a Viral Nuclear Antigen After Autophagy

  2005influential reference
• Towards a cellular definition of CD8+ T-cell memory: the role of CD4+ T-cell help in CD8+ T-cell responses.

  2004cited by this paper
• Epstein‐Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells

  2004cited by this paper
• Direct killing of Epstein-Barr virus (EBV)-infected B cells by CD4 T cells directed against the EBV lytic protein BHRF1.

  2004influential reference
• Epstein–Barr virus: 40 years on

  2004cited by this paper
• Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by autophagy

  2003influential reference
• Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells.

  2002cited by this paper
• Epstein–Barr virus–associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2

  2002cited by this paper
• Inhibition of EBV-Induced Lymphoproliferation by CD4+ T Cells Specific for an MHC Class II Promiscuous Epitope1

  2002cited by this paper
• Epstein-Barr Nuclear Antigen 1-Specific CD4+ Th1 Cells Kill Burkitt’s Lymphoma Cells1

  2002cited by this paper
• Differential Immunogenicity of Epstein-Barr Virus Latent-Cycle Proteins for Human CD4+ T-Helper 1 Responses

  2001cited by this paper
• Efficient Presentation of Both Cytosolic and Endogenous Transmembrane Protein Antigens on MHC Class II Is Dependent on Cytoplasmic Proteolysis1

  2001cited by this paper
• Complete regression of posttransplant lymphoproliferative disease using partially HLA-matched Epstein Barr virus-specific cytotoxic T cells.

  2001cited by this paper
• Epstein-Barr virus-specific cytotoxic T lymphocyte responses in the blood and tumor site of Hodgkin's disease patients: implications for a T-cell-based therapy.

  2001cited by this paper
• Targeting Antigen in Mature Dendritic Cells for Simultaneous Stimulation of CD4+ and CD8+ T Cells1

  2001cited by this paper
• Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1

  2000cited by this paper
• Cytoplasmic Processing Is a Prerequisite for Presentation of an Endogenous Antigen by Major Histocompatibility Complex Class II Proteins

  2000cited by this paper
• A repetitive sequence of Epstein-Barr virus nuclear antigen 6 comprises overlapping T cell epitopes which induce HLA-DR-restricted CD4(+) T lymphocytes.

  2000influential reference
• The Epstein–Barr virus lytic program is controlled by the co‐operative functions of two transactivators

  2000cited by this paper
• Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease.

  1999cited by this paper
• Identification of MAGE-3 Epitopes Presented by HLA-DR Molecules to CD4+ T Lymphocytes

  1999cited by this paper
• Efficient Class II Major Histocompatibility Complex Presentation of Endogenously Synthesized Hepatitis C Virus Core Protein by Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Lines to CD4+ T Cells

  1998cited by this paper
• Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine.

  1998cited by this paper
• Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients.

  1998cited by this paper
• Class I processing-defective Burkitt's lymphoma cells are recognized efficiently by CD4+ EBV-specific CTLs.

  1997cited by this paper
• Targeting Epstein-Barr virus nuclear antigen 1 (EBNA1) through the class II pathway restores immune recognition by EBNA1-specific cytotoxic T lymphocytes: evidence for HLA-DM-independent processing.

  1997cited by this paper
• Major Histocompatibility Complex Class II-dependent Unfolding, Transport, and Degradation of Endogenous Proteins*

  1997cited by this paper
• Conserved CTL epitopes within EBV latent membrane protein 2: a potential target for CTL-based tumor therapy.

  1997cited by this paper
• Human CD8+ T cell responses to EBV EBNA1: HLA class I presentation of the (Gly-Ala)-containing protein requires exogenous processing.

  1997cited by this paper
• B lymphocytes secrete antigen-presenting vesicles

  1996cited by this paper
• Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen.

  1996cited by this paper
• Processing of a viral glycoprotein in the endoplasmic reticulum for class II presentation

  1995cited by this paper
• Presentation of endogenous viral proteins in association with major histocompatibility complex class II: On the role of intracellular compartmentalization, invariant chain and the TAP transporter system

  1995cited by this paper
• Isolation of cytotoxic T lymphocytes from healthy seropositive individuals specific for peptide epitopes from Epstein-Barr virus nuclear antigen 1: implications for viral persistence and tumor surveillance.

  1995cited by this paper
• Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens.

  1995cited by this paper
• Restoration of endogenous antigen processing in Burkitt's lymphoma cells by Epstein‐Barr virus latent membrane protein‐1: coordinate up‐regulation of peptide transporters and HLA‐class I antigen expression

  1995cited by this paper
• Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3.

  1994cited by this paper
• Endoplasmic reticulum signal sequence facilitated transport of peptide epitopes restores immunogenicity of an antigen processing defective tumour cell line.

  1994cited by this paper
• Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide

  1993cited by this paper
• Multiple HLA A11-restricted cytotoxic T-lymphocyte epitopes of different immunogenicities in the Epstein-Barr virus-encoded nuclear antigen 4

  1993cited by this paper
• Presentation of cytosolic antigen by HLA-DR requires a function encoded in the class II region of the MHC.

  1993cited by this paper
• Localization of Epstein-Barr virus cytotoxic T cell epitopes using recombinant vaccinia: implications for vaccine development

  1992cited by this paper
• Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells

  1992cited by this paper
• Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies

  1992cited by this paper
• MHC class II-restricted presentation of intracellular antigen.

  1991cited by this paper
• An endogenous processing pathway in vaccinia virus-infected cells for presentation of cytoplasmic antigens to class II-restricted T cells

  1990cited by this paper
• Anchor sequence-dependent endogenous processing of human immunodeficiency virus 1 envelope glycoprotein gp160 for CD4+ T cell recognition

  1990cited by this paper
• Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen

  1988cited by this paper
• 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes.

  1982cited by this paper
• The purification fo four strains of poxvirus.

  1962cited by this paper

• The molecular regulation of autophagy in antimicrobial immunity

  2022cites this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

  2021cites this paper
• Cytotoxic CD4+ T-cells specific for EBV capsid antigen BORF1 are maintained in long-term latently infected healthy donors

  2021cites this paper
• Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway

  2019cites this paper
• Chaperone protein HSC70 regulates intercellular transfer of Y chromosome antigen DBY.

  2019cites this paper
• Autophagy and Viral Infection

  2019cites this paper
• Epstein–Barr virus strain heterogeneity impairs human T-cell immunity

  2018cites this paper
• Harnessing CD4+ T cell effectors for lymphoma therapy

  2018cites this paper
• Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival

  2018cites this paper
• Epstein-Barr virus and multiple sclerosis: investigating EBV antigen-induced T-cell cross-recognition of central nervous system proteins

  2017cites this paper
• Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4+ T Cells

  2016cites this paper
• The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer

  2016cites this paper
• Development of MHC class II-restricted TCR gene therapy for Epstein Barr virus associated malignancies

  2016influential citation
• Epstein-Barr Virus-Specific Humoral Immune Responses in Health and Disease.

  2015cites this paper
• T-Cell Responses to EBV.

  2015cites this paper
• T cells specific for different latent and lytic viral proteins efficiently control Epstein-Barr virus-transformed B cells.

  2015cites this paper
• The immunology of Epstein-Barr virus-induced disease.

  2015cites this paper
• EBV-Associated Cancer and Autoimmunity: Searching for Therapies

  2015cites this paper
• Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways

  2015cites this paper
• Transfer T Cells after Intercellular Antigen + CD 4 Direct Recognition of Melanoma Cells by The Tumor Antigen NY-ESO-1 Mediates and

  2015cites this paper
• Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses

  2015cites this paper
• Investigating the role of Epstein-Barr virus in the pathogenesis of Multiple Sclerosis

  2015cites this paper
• Epstein Barr Virus Volume 2

  2015cites this paper
• Re-examining class-I presentation and the DRiP hypothesis.

  2014cites this paper
• Regulation of Autophagic Activation by Rta of Epstein-Barr Virus via the Extracellular Signal-Regulated Kinase Pathway

  2014cites this paper
• Modified Vaccinia Virus Ankara-Infected Dendritic Cells Present CD4+ T-Cell Epitopes by Endogenous Major Histocompatibility Complex Class II Presentation Pathways

  2014cites this paper
• A game of survival: herpesvirus strategies of autophagy manipulation.

  2014cites this paper
• Autophagy in Immune Responses to Viruses

  2014cites this paper
• Cellular immune controls over Epstein-Barr virus infection: new lessons from the clinic and the laboratory.

  2014cites this paper
• Substrate-Induced Protein Stabilization Reveals a Predominant Contribution from Mature Proteins to Peptides Presented on MHC Class I

  2013cites this paper
• The biological basis and clinical correlates of the association between EBV-positive Hodgkin lymphoma and HLA class I

  2013cites this paper
• and Macrophages Mediated by Class A Transfer between Human B Lymphocytes Editing Antigen Presentation: Antigen

  2013cites this paper
• Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance

  2013cites this paper
• MHC II tetramers visualize human CD4+ T cell responses to Epstein–Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response

  2013cites this paper
• MHC Class I Mature Proteins to Peptides Presented on Reveals a Predominant Contribution from Substrate-Induced Protein Stabilization

  2013cites this paper
• Nonclassical Antigen-Processing Pathways Are Required for MHC Class II–Restricted Direct Tumor Recognition by NY-ESO-1–Specific CD4+ T Cells

  2013cites this paper
• The role of virus-specific CD4+ T cells in the control of Epstein-Barr virus infection.

  2012cites this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  2012cites this paper
• Herpesviruses Placating the Unwilling Host: Manipulation of the MHC Class II Antigen Presentation Pathway

  2012cites this paper
• HOW HERPESVIRUSES AND CELLS TUSSLE TO CONTROLAUTOPHAGY

  2012cites this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy

  2012cites this paper
• Heat Shock Protein 90-Mediated Peptide-Selective Presentation of Cytosolic Tumor Antigen for Direct Recognition of Tumors by CD4+ T Cells

  2012cites this paper
• Réponse cellulaire pan-spécifique : analyse de la présentation d’antigènes conservés du virus de l’influenza

  2011cites this paper
• Cytotoxic CD4+ T Cell Responses to EBV Contrast with CD8 Responses in Breadth of Lytic Cycle Antigen Choice and in Lytic Cycle Recognition

  2011influential citation
• Cycle Recognition Lytic Cycle Antigen Choice and in Lytic Contrast with CD8 Responses in Breadth of T Cell Responses to EBV + Cytotoxic CD4

  2011influential citation
• Immune defence against EBV and EBV-associated disease.

  2011cites this paper
• Phase I/II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma

  2011cites this paper
• The multiple roles of autophagy in cancer

  2011cites this paper
• The T-Cell Immune Response against Kaposi's Sarcoma-Associated Herpesvirus

  2011cites this paper
• Herpesviruses and Autophagy: Catch Me If You Can!

  2010cites this paper
• Viral pathophysiology of multiple sclerosis: A role for Epstein-Barr virus infection?

  2010cites this paper
• Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display

  2010cites this paper
• Epstein–Barr Virus and Multiple Sclerosis

  2010cites this paper
• Autophagy and adaptive immunity

  2010cites this paper
• Role of CD4+ Cytotoxic T Lymphocytes in the Control of Viral Diseases and Cancer

  2010cites this paper
• Exosome-Driven Antigen Transfer for MHC Class II Presentation Facilitated by the Receptor Binding Activity of Influenza Hemagglutinin

  2010cites this paper
• Characterising the adaptive t-cell immune response against Kaposi’s sarcoma-associated herpesvirus

  2010cites this paper
• HemagglutininReceptor Binding Activity of Influenza Class II Presentation Facilitated by the Exosome-Driven Antigen Transfer for MHC

  2010cites this paper
• Burkitt's lymphoma: The Rosetta Stone deciphering Epstein-Barr virus biology

  2009cites this paper
• Techniques to Study Autophagy in Plants

  2009cites this paper
• Autophagy and Its Role in MHC-Mediated Antigen Presentation1

  2009cites this paper
• Autophagy as an antimicrobial strategy

  2009cites this paper
• Autophagy and pattern recognition receptors in innate immunity

  2009cites this paper
• Epstein–Barr virus and multiple sclerosis

  2009cites this paper
• eview urkitt ’ s lymphoma : The Rosetta Stone deciphering Epstein-Barr virus biology

  2009cites this paper
• T Cell Detection of a B-Cell Tropic Virus Infection: Newly-Synthesised versus Mature Viral Proteins as Antigen Sources for CD4 and CD8 Epitope Display

  2009cites this paper
• CD4+ T-cell clones recognizing human lymphoma-associated antigens: generation by in vitro stimulation with autologous Epstein-Barr virus-transformed B cells.

  2009cites this paper
• Autophagy, antiviral immunity, and viral countermeasures

  2009cites this paper
• The latent membrane protein 1 oncogene modifies B-cell physiology by regulating autophagy

  2008cites this paper
• Definition of the peptide binding motif within DRB1*1401 restricted epitopes by peptide competition and structural modeling.

  2008cites this paper
• Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger Receptors1

  2008cites this paper
• Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products.

  2008cites this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

  2008cites this paper
• Antigens and Autophagy: The Path Less Travelled?

  2007cites this paper
• Cytosol to Lysosome Transport of Intracellular Antigens During Immune Surveillance

  2007cites this paper
• Immunodominance of Lytic Cycle Antigens in Epstein-Barr Virus-Specific CD4+ T Cell Preparations for Therapy

  2007cites this paper
• A CD8 T cell immune evasion protein specifi c to Epstein-Barr virus and its close relatives in Old World primates

  2007cites this paper
• A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates

  2007cites this paper
• Unveiling the roles of autophagy in innate and adaptive immunity

  2007cites this paper
• Cellular responses to viral infection in humans: lessons from Epstein-Barr virus.

  2007cites this paper
• T Cells + Tumors by Cd4 Tumor Antigen for Direct Recognition of Peptide-selective Presentation of Cytosolic Heat Shock Protein 90-mediated

  year unknowncites this paper