Suitability of near-infrared methods for the determination of moisture in a freeze-dried injection product containing different amounts of the active ingredient.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Pharmaceutical and Biomedical Analysis

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/0731-7085(93)80084-EPMID 8123715
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Near infrared reflectance analysis: features and applications in pharmaceutical and biomedical analysis.

  1993cited by this paper
• Development and transferability of near-infrared methods for determination of moisture in a freeze-dried injection product.

  1993cited by this paper
• Near-Infrared Spectroscopic Determination of Residual Moisture in Lyophilized Sucrose Through Intact Glass Vials

  1989cited by this paper
• Uses of near-infrared spectroscopy in pharmaceutical analysis

  1987cited by this paper

• A Review on Pharmaceutical and Bio-Allied Applications of Infrared Spectroscopy.

  2025cites this paper
• Noninvasive moisture detection in lyophilized drug product using NIR spectrometer and headspace moisture analyzer.

  2022cites this paper
• Near Infrared and Frequency Modulated Spectroscopy as Non-invasive methods for Moisture Assessment of Freeze-Dried Biologics.

  2021cites this paper
• Analytical Techniques for Structural Characterization of Proteins in Solid Pharmaceutical Forms: An Overview

  2021cites this paper
• Model-based design of secondary drying using in-line near-infrared spectroscopy data

  2021cites this paper
• Evaluation of the robustness of a novel NIR-based technique to measure the residual moisture in freeze-dried products.

  2021cites this paper
• Application of Near-Infrared Spectroscopy to statistical control in freeze-drying processes.

  2021cites this paper
• Near-infrared spectroscopy to determine residual moisture in freeze-dried products: model generation by statistical design of experiments.

  2019cites this paper
• Multi-resonance Microwave Sensors for Moisture Monitoring in Fluid-bed Processes

  2019influential citation
• Influence of controlled ice nucleation on the freeze-drying of pharmaceutical products: the secondary drying step.

  2017cites this paper
• Spectroscopic evaluation of a freeze-dried vaccine during an accelerated stability study.

  2016cites this paper
• Advances in Process Analytical Technology in Freeze-Drying

  2015cites this paper
• FTIR spectroscopy for the detection and evaluation of live attenuated viruses in freeze dried vaccine formulations

  2015cites this paper
• Near-infrared spectroscopic analysis of the breaking force of extended-release matrix tablets prepared by roller-compaction: influence of plasticizer levels and sintering temperature

  2015cites this paper
• Granulation, drying, and coating

  2014cites this paper
• Evaluation of the moisture prediction capability of near-infrared and attenuated total reflectance fourier transform infrared spectroscopy using superdisintegrants as model compounds.

  2014cites this paper
• Controlled ice nucleation in the field of freeze-drying: fundamentals and technology review.

  2013cites this paper
• Near‐infrared spectroscopic evaluation of lyophilized viral vaccine formulations

  2013cites this paper
• In-line multipoint near-infrared spectroscopy for moisture content quantification during freeze-drying.

  2013cites this paper
• Quality by Design in the Secondary Drying Step of a Freeze-Drying Process

  2012cites this paper
• Monitoring of the secondary drying in freeze-drying of pharmaceuticals.

  2011cites this paper
• On‐Line PAT Applications of Spectroscopy in the Pharmaceutical Industry

  2010cites this paper
• Process Analytical Technologies (PAT) in freeze-drying of parenteral products

  2009cites this paper
• Applying spectral peak area analysis in near-infrared spectroscopy moisture assays.

  2007cites this paper
• A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies.

  2007cites this paper
• Near infrared spectroscopy in the development of solid dosage forms

  2007cites this paper
• Near-infrared spectroscopy applications in pharmaceutical analysis.

  2007cites this paper
• Physical Characterization of Pharmaceutical Formulations in Frozen and Freeze-Dried Solid States: Techniques and Applications in Freeze-Drying Development

  2006cites this paper
• Near-infrared spectroscopy and imaging: basic principles and pharmaceutical applications.

  2005cites this paper
• Strategies for constructing the calibration set for a near infrared spectroscopic quantitation method.

  2004cites this paper
• Increasing process understanding of wet granulation by spectroscopic methods and dimension reduction tools

  2004cites this paper
• Near Infrared spectroscopy, a quality control tool for the different steps in the manufacture of herbal medicinal products

  2003cites this paper
• Development of a Novel Multichamber Microscale Fluid Bed with In-line Near Infrared Spectroscopy and Non-invasive Electrostatic Measurement

  2003cites this paper
• Development of a Novel Multichamber Microscale Fluid Bed with In-line Near Infrared Spectroscopy and Non-invasive Electrostatic Measurement

  2003cites this paper
• Validation of Lyophilization

  2003cites this paper
• Determination of residual moisture in lyophilized protein pharmaceuticals using a rapid and non-invasive method: near infrared spectroscopy.

  2002cites this paper
• Sensitive NIRS measurement of increased moisture in stored hygroscopic freeze dried product.

  2002cites this paper
• Characterization of Wet Massing Behavior of Silicified Microcrystalline Cellulose and α-Lactose Monohydrate Using Near-Infrared Spectroscopy

  2001cites this paper
• Near-Infrared Reflectance Spectroscopy in the Measurement of Water as a Part of Multivariate Process Monitoring of Fluidised Bed Granulation Process

  2000cites this paper
• Use of the Near-Infrared Reflectance Method for Measurement of Moisture Content During Granulation

  2000cites this paper
• Evaluation of a container closure integrity test model using visual inspection with confirmation by near infra-red spectroscopic analysis.

  2000cites this paper
• In-line moisture measurement during granulation with a four-wavelength near infrared sensor: an evaluation of particle size and binder effects.

  2000cites this paper
• Diffuse reflectance near-infrared spectroscopy as a nondestructive analytical technique for polymer implants.

  1999cites this paper
• Evaluation of key sources of variability in the measurement of pharmaceutical drug products by near infrared reflectance spectroscopy.

  1998cites this paper
• Quantification of an Active Substance in a Tablet by NIR and Raman Spectroscopy

  1998cites this paper
• Near-infrared spectroscopy in the pharmaceutical industry.

  1998cites this paper
• The use of near-infrared spectroscopy in the efficient prediction of a specification for the residual moisture content of a freeze-dried product.

  1998cites this paper
• Process control and end-point determination of a fluid bed granulation by application of near infra-red spectroscopy

  1997cites this paper
• Development and Validation of an Analytical Method for Identification of Granulated Nicarbazin by near Infrared Reflectance Spectroscopy

  1997cites this paper
• Determination of SB 216469-S during tablet production using near-infrared reflectance spectroscopy.

  1996cites this paper
• Vibrational spectrometry for the assessment of active substance in metoprolol tablets: a comparison between transmission and diffuse reflectance near-infrared spectrometry.

  1996cites this paper
• Pharmaceuticals and related drugs.

  1995cites this paper