Aldosterone stimulates gene expression of hepatic gluconeogenic enzymes through the glucocorticoid receptor in a manner independent of the protein kinase B cascade.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Endocrine journal

• Publication date

  2004-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1507/ENDOCRJ.51.243PMID 15118277
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Insulin action in primary hyperaldosteronism before and after surgical or pharmacological treatment.

  2012cited by this paper
• Crosstalk between insulin and angiotensin II signalling systems.

  2009cited by this paper
• The effect of aldosterone on glucose metabolism

  2003cited by this paper
• Expression and modulation of steroidogenic acute regulatory protein messenger ribonucleic acid in rat cardiocytes and after myocardial infarction.

  2003cited by this paper
• Epigallocatechin Gallate, a Constituent of Green Tea, Represses Hepatic Glucose Production*

  2002cited by this paper
• Can primary hyperaldosteronism be considered as a specific form of diabetes mellitus?

  2001cited by this paper
• Mineralocorticoid and glucocorticoid receptors inhibit UCP expression and function in brown adipocytes.

  2001cited by this paper
• Genetic variation in aldosterone synthase predicts plasma glucose levels

  2001cited by this paper
• A new human MR splice variant is a ligand-independent transactivator modulating corticosteroid action.

  2001cited by this paper
• Minireview: 11beta-hydroxysteroid dehydrogenase type 1- a tissue-specific amplifier of glucocorticoid action.

  2001cited by this paper
• Insulin-regulated gene expression.

  2001cited by this paper
• Regulation of glucose-6-phosphatase gene expression by protein kinase Balpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity.

  2000cited by this paper
• Printed in U.S.A. Copyright © 2001 by The Endocrine Society Minireview: 11�-Hydroxysteroid Dehydrogenase Type 1— A Tissue-Specific Amplifier of Glucocorticoid Action*

  2000cited by this paper
• Specificity in mineralocorticoid versus glucocorticoid action.

  2000cited by this paper
• Regulation of Glucose-6-phosphatase Gene Expression by Protein Kinase Bα and the Forkhead Transcription Factor FKHR

  2000cited by this paper
• Dehydroepiandrosterone suppresses elevated hepatic glucose-6-phosphatase mRNA level in C57BL/KsJ-db/db mice: comparison with troglitazone.

  2000cited by this paper
• Leptin levels are suppressed in primary aldosteronism.

  1999cited by this paper
• Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence.

  1999cited by this paper
• Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison with troglitazone.

  1999cited by this paper
• Diabetes Affects Similarly the Catalytic Subunit and Putative Glucose-6-phosphate Translocase of Glucose-6-phosphatase*

  1999cited by this paper
• Visceral obesity and insulin resistance are associated with plasma aldosterone levels in women.

  1999cited by this paper
• Central Role for Phosphatidylinositide 3-Kinase in the Repression of Glucose-6-phosphatase Gene Transcription by Insulin*

  1998cited by this paper
• Mineralocorticoid receptor splice variants in different human tissues.

  1998cited by this paper
• Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.

  1997cited by this paper
• Cloning and sequencing of the 5′ region of the human glucose‐6‐phosphatase gene: transcriptional regulation by cAMP, insulin and glucocorticoids in H4IIE hepatoma cells

  1996cited by this paper
• Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin

  1995cited by this paper
• Increased insulin sensitivity in patients with aldosterone producing adenoma

  1994cited by this paper
• Isolation of a cDNA for the catalytic subunit of rat liver glucose-6-phosphatase: regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP.

  1994cited by this paper
• Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.

  1987cited by this paper
• Effect of adrenal steroids on insulin release from cultured rat islets of Langerhans

  1986cited by this paper
• Improvement of growth hormone response to stimulation in primary aldosteronism with correction of potassium deficiency.

  1976cited by this paper
• Cationic Environment and Dynamics of Insulin Secretion: II. Effect of a High Concentration of Potassium

  1974cited by this paper
• Glucose Intolerance with Hypokalemia: Failure of Short-term Potassium Depletion in Normal Subjects to Reproduce the Glucose and Insulin Abnormalities of Clinical Hypokalemia

  1973cited by this paper
• HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

  1969cited by this paper
• Hypertension, the potassium ion and impaired carbohydrate tolerance.

  1965cited by this paper

• A novel mineralocorticoid receptor blocker, CS-3150, improves insulin resistance and reduces inflammation in db/db mice

  2025cites this paper
• Maternal nutrient metabolism in the liver during pregnancy

  2024cites this paper
• Chronic unpredictable mild stress increases serum aldosterone without affecting corticosterone levels and induces hepatic steatosis and renal injury in young adult male rats

  2024cites this paper
• Diabete e sindrome metabolica nel paziente con iperaldosteronismo primario

  2024cites this paper
• Secondary diabetes mellitus due to primary aldosteronism

  2022cites this paper
• Differences in Glycemic Abnormalities Between Primary Aldosteronism and Essential Hypertension: A Systematic Review and Meta-Analysis

  2022cites this paper
• Themed Issue: Emerging Fields for Therapeutic Targeting of the Aldosterone-Mineralocorticoid Receptor Signaling Pathway

  2022influential citation
• Insulin sensitivity and pancreatic β-cell function in patients with primary aldosteronism

  2021cites this paper
• Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model

  2021cites this paper
• Links between aldosterone excess and metabolic complications: A comprehensive review.

  2020cites this paper
• Assessment of Glycometabolism Impairment and Glucose Variability Using Flash Glucose Monitoring System in Patients With Adrenal Diseases

  2020cites this paper
• Impact of Endocrine Disorders on the Liver

  2020cites this paper
• Endocrine Diseases and the Liver: An Update.

  2019cites this paper
• Impaired Glucose Metabolism in Primary Aldosteronism Is Associated With Cortisol Cosecretion.

  2019cites this paper
• Associations between primary aldosteronism and diabetes, poor bone health, and sleep apnea—what do we know so far?

  2019cites this paper
• Emerging Role of Aldosterone in Mediating the Vicious Cycle of Obesity, Insulin Resistance and Metabolic Syndrome

  2018cites this paper
• Design of the Magnetic Resonance Imaging Evaluation of Mineralocorticoid Receptor Antagonism in Diabetic Atherosclerosis (MAGMA) Trial

  2017cites this paper
• The effects of goutweed (Aegopodium podagraria L.) preparations on glycemia in intact rats and against the background of metformin

  2017cites this paper
• Caveolin 1 Modulates Aldosterone‐Mediated Pathways of Glucose and Lipid Homeostasis

  2016cites this paper
• Adrenal disorders and non-alcoholic fatty liver disease.

  2016cites this paper
• АЛЬДОСТЕРОН И ОЖИРЕНИЕ: ГДЕ ИСКАТЬ КЛЮЧ К ТЕРАПИИ?

  2016cites this paper
• Glucose Metabolism in Primary Aldosteronism

  2015cites this paper
• The necessity and effectiveness of mineralocorticoid receptor antagonist in the treatment of diabetic nephropathy

  2015cites this paper
• Effects of Aegopodium podagraria Preparations on the Metabolic Disorders Induced in Rats by Excess Fructose Combined WITH Hydrochlorothiazide: The Relationship between Influence on Electrolyte and Carbohydrate Metabolism.

  2014cites this paper
• Revisión Aldosterone : a cardiometabolic risk hormone ?

  2014cites this paper
• Aldosterone: a cardiometabolic risk hormone?

  2014cites this paper
• Effects of aldosterone on insulin sensitivity and secretion.

  2014cites this paper
• Diabetes-Ameliorating Effects of Fermented Red Ginseng and Causal Effects on Hormonal Interactions: Testing the Hypothesis by Multiple Group Path Analysis

  2013cites this paper
• The mineralocorticoid receptor: a new player controlling energy homeostasis

  2013cites this paper
• Aldosterone, mineralocorticoid receptor and the metabolic syndrome: role of the mineralocorticoid receptor antagonists.

  2012cites this paper
• Excess aldosterone-induced changes in insulin signaling molecules and glucose oxidation in gastrocnemius muscle of adult male rat

  2012cites this paper
• The Role of Aldosterone in the Metabolic Syndrome

  2011cites this paper
• Aldosterone Perturbs Adiponectin and PAI-1 Expression and Secretion in 3T3-L1 Adipocytes

  2011cites this paper
• Effect of spironolactone and vitamin E on serum metabolic parameters and insulin resistance in patients with nonalcoholic fatty liver disease

  2011cites this paper
• Primary Aldosteronism and Metabolic Syndrome

  2011cites this paper
• Aldosterone, from (patho)physiology to treatment in cardiovascular and renal damage.

  2011cites this paper
• Diabetic Lipoproteins and Adrenal Aldosterone Synthesis – A Possible Pathophysiological Link?

  2011cites this paper
• Aldosterone: role in edematous disorders, hypertension, chronic renal failure, and metabolic syndrome.

  2010cites this paper
• Role of Adenosine A1 Receptors in Native Coronary Atherosclerosis, In-stent Stenosis, and Coronary Blood Flow Regulation in Metabolic Syndrome and Exercise

  2010cites this paper
• Impact of excess aldosterone on glucose homeostasis in adult male rat.

  2009cites this paper
• Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in GR-deficient BE(2)C and T84 cells in vitro.

  2009cites this paper
• A Central Role of RLIP76 in Regulation of Glycemic Control

  2009cites this paper
• Aldosterone and cardiovascular risk

  2009cites this paper
• Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.

  2009cites this paper
• The metabolic syndrome in primary aldosteronism

  2008cites this paper
• Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat.

  2008cites this paper
• Aldosterone and Metabolic Syndrome: Is Increased Aldosterone in Metabolic Syndrome Patients an Additional Risk Factor?

  2008cites this paper
• Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor.

  2007cites this paper
• Aldosterone Suppresses Insulin Signaling Via the Downregulation of Insulin Receptor Substrate-1 in Vascular Smooth Muscle Cells

  2007cites this paper
• The association of aldosterone with obesity-related hypertension and the metabolic syndrome.

  2007cites this paper
• Aldosterone as a key mediator of the cardiometabolic syndrome in primary aldosteronism: an observational study

  2007cites this paper
• The metabolic syndrome in primary aldosteronism

  2007cites this paper
• Mineralocorticoid receptor is involved in the regulation of genes responsible for hepatic glucose production.

  2006cites this paper
• Role of the renin-angiotensin- aldosterone system in the metabolic syndrome.

  2006cites this paper
• Molecular Mechanism of the Inhibitory Effect of Aldosterone on Endothelial NO Synthase Activity

  2006cites this paper
• Effects of dehydroepiandrosterone on gluconeogenic enzymes and glucose uptake in human hepatoma cell line, HepG2.

  2005cites this paper
• Aldosterone and end-organ damage

  2005cites this paper
• Shimatsu, Yasunobu Hirata and Mitsuhide Naruse Activity Molecular Mechanism of the Inhibitory Effect of Aldosterone on Endothelial No Synthase Molecular Mechanism of the Inhibitory Effect of Aldosterone on Endothelial No Synthase Activity Aldosterone and Vascular Endothelium Construction of Gtp Cycl

  year unknowncites this paper