Association Between SLC16A5 Genetic Variation and Cisplatin-Induced Ototoxic Effects in Adult Patients With Testicular Cancer

No abstract is available for this paper.

• Publication year

  2017

• Venue

  JAMA Oncology

• Publication date

  2017-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1001/jamaoncol.2017.0502PMID 28448657PMCID PMC5824214
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• SHIELD: an integrative gene expression database for inner ear research

  2015cited by this paper
• Gene Expression by Mouse Inner Ear Hair Cells during Development

  2015cited by this paper
• Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.

  2015cited by this paper
• Repurposing drugs in oncology (ReDO)—cimetidine as an anti-cancer agent

  2014cited by this paper
• Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy

  2013cited by this paper
• Pharmacogenomics Knowledge for Personalized Medicine

  2012cited by this paper
• Prediction of copper transport protein 1 (CTR1) genotype on severe cisplatin induced toxicity in non-small cell lung cancer (NSCLC) patients.

  2012cited by this paper
• Cisplatin ototoxicity in rat cochlear organotypic cultures.

  2011cited by this paper
• Understanding the contribution of synonymous mutations to human disease

  2011cited by this paper
• Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions.

  2010cited by this paper
• Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy

  2009cited by this paper
• Transient ribosomal attenuation coordinates protein synthesis and co-translational folding

  2009cited by this paper
• FUNCTIONAL CHARACTERIZATION OF HUMAN MONOCARBOXYLATE TRANSPORTER 6 (SLC16A5)

  2005cited by this paper
• Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer.

  1998cited by this paper
• Codon usage and tRNA content in unicellular and multicellular organisms.

  1985cited by this paper

• Role of solute carrier transporters in the biodistribution and toxicity of chemotherapeutic drugs.

  2026cites this paper
• Strategies to Mitigate Cisplatin-Induced Ototoxicity: A Literature Review of Protective Agents, Mechanisms, and Clinical Gaps

  2025cites this paper
• Comparison of associations suggests mainly distinct pools of genetic risk factors contribute to cisplatin-induced hearing loss and hearing difficulty in the general population

  2025cites this paper
• The Role of Genetic and Non-Genetic Factors in the Occurrence of Cisplatin-Associated Ototoxicity

  2025cites this paper
• Combined genetic polymorphisms of the GSTT1 and NRF2 genes increase susceptibility to cisplatin-induced ototoxicity: A preliminary study.

  2024cites this paper
• Cisplatin-Induced Hearing Loss, Oxidative Stress, and Antioxidants as a Therapeutic Strategy—A State-of-the-Art Review

  2024cites this paper
• Impact of genetic variants in the solute carrier (SLC) genes encoding drug uptake transporters on the response to anticancer chemotherapy

  2024cites this paper
• In-silico approaches to assessing multiple high-level drug-drug and drug-disease adverse drug effects

  2024cites this paper
• Role of Cisplatin Dose Intensity and TPMT Variation in the Development of Hearing Loss in Children

  2023cites this paper
• Systematic Critical Review of Genetic Factors Associated with Cisplatin-induced Ototoxicity: Canadian Pharmacogenomics Network for Drug Safety 2022 Update

  2023influential citation
• Ototoxicity prognostic models in adult and pediatric cancer patients: a rapid review

  2023cites this paper
• Advancing the Science of Vaccine Safety During the Coronavirus Disease 2019 (COVID-19) Pandemic and Beyond: Launching an International Network of Special Immunization Services

  2022cites this paper
• Platinum-induced ototoxicity in pediatric cancer survivors: GSTP1 c.313A>G variant association

  2022cites this paper
• Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4

  2022cites this paper
• Current Understanding of Membrane Transporters as Regulators or Targets for Cisplatin-Induced Hearing Loss

  2021influential citation
• Solute carrier family 16 member 5 downregulation and its methylation might serve as a prognostic indicator of prostate cancer

  2021cites this paper
• A pan-cancer analysis revealed the role of the SLC16 family in cancer

  2021cites this paper
• Late adverse effects and quality of life in survivors of testicular germ cell tumour

  2021cites this paper
• Screening and identification of key biomarkers in clear cell renal cell carcinoma based on bioinformatics analysis

  2020cites this paper
• Application of gene therapy in auditory system diseases

  2020cites this paper
• Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease

  2020cites this paper
• Comprehensive analysis of the SLC16A gene family in pancreatic cancer via integrated bioinformatics

  2020cites this paper
• Current insights into interethnic variability in testicular cancers: Population pharmacogenetics, clinical trials, genetic basis of chemotherapy-induced toxicities and molecular signal transduction.

  2020cites this paper
• Usefulness of current candidate genetic markers to identify childhood cancer patients at risk for platinum-induced ototoxicity: Results of the European PanCareLIFE cohort study.

  2020cites this paper
• The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition

  2020cites this paper
• Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

  2020cites this paper
• Genetic Predisposition to Late Effects: Pharmacogenomics of Cisplatin-Induced Ototoxicity

  2020cites this paper
• The genetic landscape of the human solute carrier (SLC) transporter superfamily

  2019cites this paper
• Analytical Validation of Variants to Aid in Genotype-Guided Therapy for Oncology.

  2019cites this paper
• The genetic vulnerability to cisplatin ototoxicity: a systematic review

  2019cites this paper
• Weighted single-step GWAS identified candidate genes associated with semen traits in a Duroc boar population

  2019cites this paper
• Advances in Toxicological Research of the Anticancer Drug Cisplatin.

  2019cites this paper
• Testicular Cancer: Genes, Environment, Hormones

  2019cites this paper
• Outcome Definition Influences the Relationship between Genetic Polymorphisms of ERCC1, ERCC2, SLC22A2 and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients

  2019influential citation
• Pharmacogenomics of Cisplatin‐Induced Ototoxicity: Successes, Shortcomings, and Future Avenues of Research

  2019cites this paper
• Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study

  2019cites this paper
• Pharmacogenetics implementation in the clinics: information and guidelines for germline variants

  2019cites this paper
• The role of pharmacogenomics in adverse drug reactions

  2019cites this paper
• Genetic Determinants of Ototoxicity During and After Childhood Cancer Treatment: Protocol for the PanCareLIFE Study

  2019cites this paper
• Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy

  2018cites this paper
• Further Investigation of the Role of ACYP2 and WFS1 Pharmacogenomic Variants in the Development of Cisplatin-Induced Ototoxicity in Testicular Cancer Patients

  2018influential citation
• Clinical and Genetic Predictors of Aromatase Inhibitor-Induced Arthralgia

  2018cites this paper
• Analyses of Adverse Drug Reactions–Nationwide Active Surveillance Network: Canadian Pharmacogenomics Network for Drug Safety Database

  2018cites this paper
• Association between genetic polymorphisms and platinum-induced ototoxicity in children

  2018cites this paper
• [The analysis of the association of the polymorphic variants of the TPMT, COMT, and ABCC3 genes with the development of hearing disorders induced by the cisplatin treatment].

  2018cites this paper
• Pharmacogenomics of Vincristine‐Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes

  2018cites this paper
• Pharmacogenetics of drug-induced ototoxicity caused by aminoglycosides and cisplatin.

  2017influential citation