A 21-amino acid peptide from the cysteine cluster II of the family D DNA polymerase from Pyrococcus horikoshii stimulates its nuclease activity which is Mre11-like and prefers manganese ion as the cofactor.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Nucleic Acids Research

• Publication date

  2004-01-16

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/NAR/GKH153PMID 14704353PMCID PMC373266
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Eukaryotic DNA polymerases].

  2005cited by this paper
• Subunit interaction and regulation of activity through terminal domains of the family D DNA polymerase from Pyrococcus horikoshii.

  2004cited by this paper
• Subunit Interaction and Regulation of Activity through Terminal Domains of the Family D DNA Polymerase from Pyrococcus horikoshii*

  2003cited by this paper
• Tethering on the brink: the evolutionarily conserved Mre11-Rad50 complex.

  2002cited by this paper
• NurA, a novel 5′–3′ nuclease gene linked to rad50 and mre11 homologs of thermophilic Archaea

  2002cited by this paper
• Eukaryotic DNA polymerases.

  2002cited by this paper
• Structural basis for proofreading during replication of the Escherichia coli chromosome.

  2002cited by this paper
• Invariant Asp-1122 and Asp-1124 Are Essential Residues for Polymerization Catalysis of Family D DNA Polymerase fromPyrococcus horikoshii *

  2001cited by this paper
• Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.

  2001influential reference
• Crystal structure of DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis KOD1.

  2001cited by this paper
• Characterization of two DNA polymerases from the hyperthermophilic euryarchaeon Pyrococcus abyssi.

  2001cited by this paper
• Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine

  2000cited by this paper
• Identification of Conserved Residues Contributing to the Activities of Adenovirus DNA Polymerase

  2000cited by this paper
• Preliminary X-ray crystallographic and NMR studies on the exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III.

  2000cited by this paper
• DNA replication fidelity.

  2000cited by this paper
• Bacterial mode of replication with eukaryotic-like machinery in a hyperthermophilic archaeon.

  2000cited by this paper
• Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7.

  2000cited by this paper
• Mutational and pH Studies of the 3′ → 5′ Exonuclease Activity of Bacteriophage T4 DNA Polymerase*

  1999cited by this paper
• Crystal structure of an archaebacterial DNA polymerase.

  1999cited by this paper
• Archaeal DNA replication: identifying the pieces to solve a puzzle.

  1999cited by this paper
• Specific interaction between DNA polymerase II (PolD) and RadB, a Rad51/Dmc1 homolog, in Pyrococcus furiosus.

  1999cited by this paper
• A Novel mre11 Mutation Impairs Processing of Double-Strand Breaks of DNA during Both Mitosis and Meiosis

  1998cited by this paper
• Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11.

  1998cited by this paper
• Phosphoesterase domains associated with DNA polymerases of diverse origins.

  1998cited by this paper
• The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA.

  1998cited by this paper
• Role of the Putative Zinc Finger Domain of Saccharomyces cerevisiae DNA Polymerase ε in DNA Replication and the S/M Checkpoint Pathway*

  1998cited by this paper
• Complex formation and functional versatility of Mre11 of budding yeast in recombination.

  1998cited by this paper
• Nuclease Activities in a Complex of Human Recombination and DNA Repair Factors Rad50, Mre11, and p95*

  1998cited by this paper
• Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates.

  1998cited by this paper
• Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

  1998cited by this paper
• A heterodimeric DNA polymerase: evidence that members of Euryarchaeota possess a distinct DNA polymerase.

  1998influential reference
• Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution.

  1997cited by this paper
• Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69

  1997cited by this paper
• Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity

  1997cited by this paper
• Copyright © 1998, American Society for Microbiology A Novel DNA Polymerase Family Found in Archaea

  1997cited by this paper
• Raster3D: photorealistic molecular graphics.

  1997cited by this paper
• A novel DNA polymerase in the hyperthermophilic archaeon, Pyrococcus furiosus: gene cloning, expression, and characterization

  1997cited by this paper
• Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.

  1997cited by this paper
• Herpes Simplex Virus Type 1 DNA Polymerase

  1996cited by this paper
• Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.

  1995cited by this paper
• X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.

  1995cited by this paper
• Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex

  1995cited by this paper
• Crystal structure of Thermus aquaticus DNA polymerase

  1995cited by this paper
• Crystal structure of a purple acid phosphatase containing a dinuclear Fe(III)-Zn(II) active site.

  1995cited by this paper
• Mutational analysis of a Ser/Thr phosphatase. Identification of residues important in phosphoesterase substrate binding and catalysis.

  1994cited by this paper
• Yeast mitochondrial DNA mutators with deficient proofreading exonucleolytic activity.

  1992cited by this paper
• Evidence favouring the hypothesis of a conserved 3'-5' exonuclease active site in DNA-dependent DNA polymerases.

  1992cited by this paper
• Compilation and alignment of DNA polymerase sequences.

  1991cited by this paper
• A program to produce both detailed and schematic plots of protein structures

  1991cited by this paper
• Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.

  1991cited by this paper
• Structural basis for the 3′‐5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

  1991cited by this paper
• Use of polymerase chain reaction catalyzed by Taq DNA polymerase for site-specific mutagenesis.

  1989cited by this paper
• A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases.

  1989cited by this paper
• Isolation and characterization of mutants with deletions in dnaQ, the gene for the editing subunit of DNA polymerase III in Salmonella typhimurium

  1989cited by this paper
• Exonucleolytic proofreading.

  1988cited by this paper
• Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3' leads to 5' exonuclease activity in deoxyribonucleic acid polymerases.

  1972cited by this paper
• Enzymatic Synthesis of Deoxyribonucleic Acid XXXVI. A PROOFREADING FUNCTION FOR THE 3' → 5' EXONUCLEASE ACTIVITY IN DEOXYRIBONUCLEIC ACID POLYMERASES

  1972cited by this paper
• Enzymatic synthesis of deoxyribonucleic acid.

  1969cited by this paper

• Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases

  2023cites this paper
• Haloferax volcanii—a model archaeon for studying DNA replication and repair

  2020cites this paper
• Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

  2020cites this paper
• An updated structural classification of replicative DNA polymerases.

  2019cites this paper
• Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

  2019cites this paper
• Genome-Wide Characterization and Expression Analyses of Pleurotus ostreatus MYB Transcription Factors during Developmental Stages and under Heat Stress Based on de novo Sequenced Genome

  2018cites this paper
• Elucidating functions of DP1 and DP2 subunits from the Thermococcus kodakarensis family D DNA polymerase

  2018cites this paper
• Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography

  2016cites this paper
• Synthesis of protected 2′-O-deoxyribonucleotides on a precipitative soluble support: a useful procedure for the preparation of trimer phosphoramidites

  2016cites this paper
• Pre-steady-state Kinetic Analysis of a Family D DNA Polymerase from Thermococcus sp. 9°N Reveals Mechanisms for Archaeal Genomic Replication and Maintenance*

  2015cites this paper
• Serial intermediates with a 1 nt 3′-flap and 5′ variable-length flaps are formed by cooperative functioning of Pyrococcus horikoshii FEN-1 with either B or D DNA polymerases

  2014cites this paper
• Characterization of Family D DNA polymerase from Thermococcus sp. 9°N

  2014cites this paper
• Archaeal DNA Polymerases: Enzymatic Abilities, Coordination, and Unique Properties

  2014cites this paper
• Thermostable DNA polymerases in replication, repair and biotechnology

  2014influential citation
• Domain Structures and Inter-Domain Interactions Defining the Holoenzyme Architecture of Archaeal D-Family DNA Polymerase

  2013cites this paper
• The Eukaryotic Replisome: a Guide to Protein Structure and Function

  2012cites this paper
• The Pol α-primase complex.

  2012cites this paper
• Novel structure of an N‐terminal domain that is crucial for the dimeric assembly and DNA‐binding of an archaeal DNA polymerase D large subunit from Pyrococcus horikoshii

  2011cites this paper
• Regulation of cell cycle and DNA repair in post-mitotic GABA neurons in psychotic disorders.

  2011cites this paper
• The glycine-rich motif of Pyrococcus abyssi DNA polymerase D is critical for protein stability.

  2010cites this paper
• Investigation of Noncanonical DNA Polymerases and Their Mechanisms

  2009cites this paper
• A highly conserved family of inactivated archaeal B family DNA polymerases

  2008cites this paper
• Improvement of an Unusual Twin-Arginine Transporter Leader Peptide by a Codon-Based Randomization Approach

  2006cites this paper
• Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase.

  2006cites this paper
• The catalytic mechanisms of binuclear metallohydrolases.

  2006cites this paper
• The screening of expression and purification conditions for replicative DNA polymerase associated B-subunits, assignment of the exonuclease activity to the C-terminus of archaeal pol D DP1 subunit.

  2005cites this paper
• The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication.

  2005cites this paper
• Domain topology of the DNA polymerase D complex from a hyperthermophilic archaeon Pyrococcus horikoshii.

  2004cites this paper
• Replicative DNA polymerase associated B-subunits

  2004cites this paper
• Characterization of the 3' exonuclease subunit DP1 of Methanococcus jannaschii replicative DNA polymerase D.

  2004cites this paper
• REPLICATIVE DNA POLYMERASE ASSOCIATED B-SUBUNITS

  2004cites this paper
• REPLICATIVE DNA POLYMERASE ASSOCIATED B-SUBUNITS MAARIT JOKELA

  2004cites this paper