Influence of Ghrelin and Growth Hormone Deficiency on AMP‐Activated Protein Kinase and Hypothalamic Lipid Metabolism

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of neuroendocrinology

• Publication date

  2010-03-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-2826.2010.01994.xPMID 20298456
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hypothalamic lipotoxicity and the metabolic syndrome.

  2010cited by this paper
• Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion.

  2009cited by this paper
• Endoplasmic reticulum stress plays a central role in development of leptin resistance.

  2009cited by this paper
• UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

  2009cited by this paper
• Glucocorticoids increase neuropeptide Y and agouti-related peptide gene expression via adenosine monophosphate-activated protein kinase signaling in the arcuate nucleus of rats.

  2008cited by this paper
• UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals

  2008cited by this paper
• Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

  2008cited by this paper
• Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats.

  2008cited by this paper
• The Orexigenic Effect of Ghrelin Is Mediated through Central Activation of the Endogenous Cannabinoid System

  2008cited by this paper
• Key Role for AMP-Activated Protein Kinase in the Ventromedial Hypothalamus in Regulating Counterregulatory Hormone Responses to Acute Hypoglycemia

  2008cited by this paper
• Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion.

  2008cited by this paper
• Triiodothyronine (T3) stimulates food intake via enhanced hypothalamic AMP-activated kinase activity.

  2008cited by this paper
• Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling.

  2008cited by this paper
• Faculty Opinions recommendation of Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity.

  2008cited by this paper
• Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver.

  2007cited by this paper
• Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver

  2007cited by this paper
• Regulation of hypothalamic malonyl-CoA by central glucose and leptin

  2007cited by this paper
• Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

  2007cited by this paper
• Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.

  2007cited by this paper
• Tamoxifen-Induced Anorexia Is Associated With Fatty Acid Synthase Inhibition in the Ventromedial Nucleus of the Hypothalamus and Accumulation of Malonyl-CoA

  2006cited by this paper
• Molecular disruption of hypothalamic nutrient sensing induces obesity

  2006cited by this paper
• The Role of Hypothalamic Malonyl-CoA in Energy Homeostasis*

  2006cited by this paper
• Ghrelin action in the brain controls adipocyte metabolism.

  2006cited by this paper
• The brain-specific carnitine palmitoyltransferase-1c regulates energy homeostasis.

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• Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice.

  2006cited by this paper
• SREBPs: sterol-regulated transcription factors.

  2006cited by this paper
• Expression of ghrelin receptor mRNA in the rat and the mouse brain

  2006cited by this paper
• Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice.

  2006cited by this paper
• Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.

  2005cited by this paper
• From the authors

  2005cited by this paper
• Cannabinoids and Ghrelin Have Both Central and Peripheral Metabolic and Cardiac Effects via AMP-activated Protein Kinase*

  2005cited by this paper
• Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction.

  2005cited by this paper
• Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.

  2004cited by this paper
• Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

  2004cited by this paper
• AMP-activated Protein Kinase Plays a Role in the Control of Food Intake*

  2004cited by this paper
• AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

  2004cited by this paper
• Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production

  2003cited by this paper
• Hypothalamic malonyl-CoA as a mediator of feeding behavior

  2003cited by this paper
• A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans.

  2001cited by this paper
• Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors.

  2000cited by this paper
• Ghrelin-induced growth hormone secretion in humans.

  2000cited by this paper
• Ghrelin induces adiposity in rodents

  2000cited by this paper
• The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion.

  2000cited by this paper
• Importance of glucose-6-phosphate dehydrogenase activity in cell death.

  1999cited by this paper
• Ghrelin is a growth-hormone-releasing acylated peptide from stomach

  1999cited by this paper
• Importance of glucose-6-phosphate dehydrogenase activity in cell death.

  1999cited by this paper
• Hypothalamic/pituitary-axis of the spontaneous dwarf rat: autofeedback regulation of growth hormone (GH) includes suppression of GH releasing-hormone receptor messenger ribonucleic acid.

  1998cited by this paper
• Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat.

  1997cited by this paper
• A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

  1996cited by this paper
• Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat.

  1996cited by this paper
• Influence of food deprivation in the rat on hypothalamic expression of growth hormone-releasing factor and somatostatin.

  1990cited by this paper
• Growth hormone-deficient dwarfism in the rat: a new mutation.

  1988cited by this paper
• The regulation of triglyceride synthesis and fatty acid synthesis in rat epididymal adipose tissue. Effects of altered dietary and hormonal conditions.

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• Development of human growth hormone-treated chimeric mice with humanized livers for an evaluation model of drug-induced fatty liver disease

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  2025cites this paper
• Multiple metabolic signals in the CeA regulate feeding: The role of AMPK.

  2024cites this paper
• LEAP-2 Counteracts Ghrelin-Induced Food Intake in a Nutrient, Growth Hormone and Age Independent Manner

  2022cites this paper
• AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin

  2020cites this paper
• Ghrelin fiber projections from the hypothalamic arcuate nucleus into the dorsal vagal complex and the regulation of glycolipid metabolism.

  2019cites this paper
• Analyzing AMPK Function in the Hypothalamus.

  2018cites this paper
• AMP-activated protein kinase α1 in Megalobrama amblycephala: Molecular characterization and the transcriptional modulation by nutrient restriction and glucose and insulin loadings.

  2018cites this paper
• Hypothalamic AMPK and energy balance

  2018cites this paper
• Hypothalamic AMPK : a golden target against obesity ?

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• Estradiol effects on hypothalamic AMPK and BAT thermogenesis: A gateway for obesity treatment?

  2017cites this paper
• Effects of metformin on cell growth and AMPK activity in pituitary adenoma cell cultures, focusing on the interaction with adenylyl cyclase activating signals.

  2017cites this paper
• Ceramide counteracts the effects of ghrelin on the metabolic control of food intake in rainbow trout

  2017cites this paper
• The cellular and molecular bases of leptin and ghrelin resistance in obesity

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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• Ghrelin requires p53 to stimulate lipid storage in fat and liver.

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