Absence of nicotinic acetylcholine receptor α7 subunit amplifies inflammation and accelerates onset of fibrosis: an inflammatory kidney model

No abstract is available for this paper.

• Publication year

  2015

• Venue

  The FASEB Journal

• Publication date

  2015-05-18

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1096/fj.14-262493PMID 25985801PMCID PMC4511204
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Morphological and functional differentiation in BE(2)-M17 human neuroblastoma cells by treatment with Trans-retinoic acid

  2013cited by this paper
• Loss of TIMP3 underlies diabetic nephropathy via FoxO1/STAT1 interplay

  2013cited by this paper
• Coagulation and coagulation signalling in fibrosis.

  2013cited by this paper
• Overexpression of Tissue Inhibitor of Metalloproteinase 3 in Macrophages Reduces Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice

  2012cited by this paper
• Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor.

  2012cited by this paper
• Neural reflexes in inflammation and immunity

  2012cited by this paper
• TIMP3 Overexpression in Macrophages Protects From Insulin Resistance, Adipose Inflammation, and Nonalcoholic Fatty Liver Disease in Mice

  2012influential reference
• Erratum: Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

  2011cited by this paper
• Adenosine A(2A) receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation.

  2011cited by this paper
• Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit

  2011cited by this paper
• Distinct macrophage phenotypes contribute to kidney injury and repair.

  2011cited by this paper
• Suppressors of cytokine signaling abrogate diabetic nephropathy.

  2010cited by this paper
• Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor α7 subunit gene knockout mice

  2010cited by this paper
• Mechanistic connection between inflammation and fibrosis.

  2010cited by this paper
• Cellular distribution of the nicotinic acetylcholine receptor alpha7 subunit in rat hippocampus.

  2009cited by this paper
• Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice.

  2009cited by this paper
• Loss of TIMP3 enhances interstitial nephritis and fibrosis.

  2009cited by this paper
• Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease

  2009cited by this paper
• Cholinergic agonists attenuate renal ischemia-reperfusion injury in rats.

  2008cited by this paper
• Nicotinic acetylcholine receptor expression and regulation in the rat kidney after ischemia-reperfusion injury.

  2008cited by this paper
• Metalloproteinase Expression in Monocytes and Macrophages and its Relationship to Atherosclerotic Plaque Instability

  2008cited by this paper
• Inhibition of CXCL16 attenuates inflammatory and progressive phases of anti-glomerular basement membrane antibody-associated glomerulonephritis.

  2007cited by this paper
• Chemokine receptor CXCR3 mediates T cell recruitment and tissue injury in nephrotoxic nephritis in mice.

  2007cited by this paper
• Nicotine Protects Kidney from Renal Ischemia/Reperfusion Injury through the Cholinergic Anti-Inflammatory Pathway

  2007cited by this paper
• SOCS proteins, cytokine signalling and immune regulation

  2007cited by this paper
• Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases.

  2007cited by this paper
• The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice.

  2006cited by this paper
• Conditional ablation of macrophages halts progression of crescentic glomerulonephritis.

  2005influential reference
• Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

  2005cited by this paper
• Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha.

  2005cited by this paper
• Biomarkers of inflammation and progression of chronic kidney disease.

  2005cited by this paper
• Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair.

  2005cited by this paper
• Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis.

  2005cited by this paper
• Role of the coagulation/fibrinolysis system in fibrin-associated glomerular injury.

  2004cited by this paper
• Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells.

  2003cited by this paper
• Mononuclear cell-infiltrate inhibition by blocking macrophage-derived chemokine results in attenuation of developing crescentic glomerulonephritis.

  2003cited by this paper
• Intrinsic renal cells are the major source of tumor necrosis factor contributing to renal injury in murine crescentic glomerulonephritis.

  2003cited by this paper
• Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.

  2003influential reference
• Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation.

  2003cited by this paper
• Rat nicotinic ACh receptor α7 and β2 subunits co‐assemble to form functional heteromeric nicotinic receptor channels

  2002cited by this paper
• The inflammatory reflex

  2002cited by this paper
• Nicotinic α7 Receptor Clusters on Hippocampal GABAergic Neurons: Regulation by Synaptic Activity and Neurotrophins

  2002cited by this paper
• Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation

  2002cited by this paper
• Rat nicotinic ACh receptor alpha7 and beta2 subunits co-assemble to form functional heteromeric nicotinic receptor channels.

  2002cited by this paper
• Prevention and treatment of experimental crescentic glomerulonephritis by blocking tumour necrosis factor-alpha.

  2001cited by this paper
• Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats.

  2000cited by this paper
• Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

  2000cited by this paper
• the systemic inflammatory response to endotoxin

  2000cited by this paper
• Heparin-binding EGF-like growth factor contributes to reduced glomerular filtration rate during glomerulonephritis in rats.

  2000cited by this paper
• Remarkable roles of proteolysis on and beyond the cell surface.

  2000cited by this paper
• NF‐κB‐dependent fractalkine induction in rat aortic endothelial cells stimulated by IL‐1β, TNF‐α, and LPS

  2000cited by this paper
• NF-kappaB-dependent fractalkine induction in rat aortic endothelial cells stimulated by IL-1beta, TNF-alpha, and LPS.

  2000cited by this paper
• Extraneuronal cholinergic system in lymphocytes.

  2000cited by this paper
• A2A adenosine receptors in human peripheral blood cells

  2000cited by this paper
• Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication.

  1999cited by this paper
• Impaired Antibacterial Host Defense in Mice Lacking the N-formylpeptide Receptor

  1999cited by this paper
• In Vivo Inhibition of CC and CX3C Chemokine–induced Leukocyte Infiltration and Attenuation of Glomerulonephritis in Wistar-Kyoto (WKY) Rats by vMIP-II

  1998cited by this paper
• Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: expression and function in humans.

  1998cited by this paper
• Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers.

  1998cited by this paper
• Glomerular ICAM-1 Expression Related to Circulating TNF-α in Human Glomerulonephritis

  1997cited by this paper
• Glomerular ICAM-1 expression related to circulating TNF-alpha in human glomerulonephritis.

  1997cited by this paper
• Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides.

  1997cited by this paper
• RelB regulation of chemokine expression modulates local inflammation.

  1997cited by this paper
• Podocytes are the major source of IL-1α and IL-1β in human glomerulonephritides

  1997cited by this paper
• Ultrastructural localization of vascular cell adhesion molecule-1 in proliferative and crescentic glomerulonephritis

  1996cited by this paper
• Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody.

  1995cited by this paper
• Interleukin-1 receptor antagonist ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis.

  1994cited by this paper
• The Family of Matrix Metalloproteinasesa

  1994cited by this paper
• The family of matrix metalloproteinases.

  1994cited by this paper
• LPS-induced MCP-1, IL-1 beta, and TNF-alpha mRNA expression in isolated erythrocyte-perfused rat kidney.

  1993cited by this paper
• Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

  1990cited by this paper
• Distribution of type I collagen in human kidney diseases in comparison with type III collagen

  1990cited by this paper
• Glomerular macrophages express augmented procoagulant activity in experimental fibrin-related glomerulonephritis in rabbits.

  1988cited by this paper
• The basis for the immunoregulatory role of macrophages and other accessory cells.

  1987influential reference
• Interactions between the Neuroendocrine and Immune Systems: Common Hormones and Receptors

  1987cited by this paper
• Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum.

  1981influential reference
• Network of immune-neuroendocrine interactions.

  1977cited by this paper
• Effects of a bacterial polysaccharide (piromen) on the pituitary-adrenal axis: adrenal ascorbic acid, cholesterol and histologic alterations.

  1957cited by this paper
• Vagus nerve stimulation attenuates the systemic in ̄ ammatory response to endotoxin

  year unknowncited by this paper

• Translational implications of CHRFAM7A, an elusive human-restricted fusion gene

  2024cites this paper
• Production of Acetylcholine by Podocytes and its Protection from Kidney Injury in GN

  2024influential citation
• Nicotine aggravates liver fibrosis via α7 nicotinic acetylcholine receptor expressed on activated hepatic stellate cells in mice

  2024cites this paper
• Nicotine promotes renal interstitial fibrosis via upregulation of XIAP in an alpha7-nAChR-dependent manner.

  2023cites this paper
• Electroacupuncture Ameliorates Intestinal Barrier Destruction in Mice With Bile Duct Ligation-Induced Liver Injury by Activating the Cholinergic Anti-Inflammatory Pathway.

  2022cites this paper
• The role of advanced technologies against COVID-19: Prevention, Detection, and Treatments.

  2022cites this paper
• Up‐regulation of the human‐specific CHRFAM7A gene protects against renal fibrosis in mice with obstructive nephropathy

  2022cites this paper
• The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice

  2021cites this paper
• Cigarette smoke promotes oral leukoplakia via regulating glutamine metabolism and M2 polarization of macrophage

  2021cites this paper
• Expression of the α7 Nicotinic Acetylcholine Receptor Is Critically Required for the Antifibrotic Effect of PHA-543613 on Skin Fibrosis

  2021cites this paper
• Systemic Administration of α7-Nicotinic Acetylcholine Receptor Ligands Does Not Improve Renal Injury or Behavior in Mice With Advanced Systemic Lupus Erythematosus

  2021cites this paper
• Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice

  2020cites this paper
• Positive Allosteric Modulation of Alpha7 Nicotinic Acetylcholine Receptors Transiently Improves Memory but Aggravates Inflammation in LPS-Treated Mice

  2020cites this paper
• The α7 nicotinic acetylcholine receptor - a promising target for the treatment of fibrotic skin disorders.

  2020cites this paper
• Cardioprotective role of GTS-21 by attenuating the TLR4/NF-κB pathway in streptozotocin-induced diabetic cardiomyopathy in rats

  2020cites this paper
• Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis

  2020cites this paper
• Cardioprotective role of GTS-21 by attenuating the TLR4/NF-κB pathway in streptozotocin-induced diabetic cardiomyopathy in rats

  2020cites this paper
• Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.

  2019cites this paper
• S‐oxiracetam ameliorates ischemic stroke induced neuronal apoptosis through up‐regulating &agr;7 nAChR and PI3K / Akt / GSK3&bgr; signal pathway in rats

  2018cites this paper
• The crosstalk of gut microbiota and chronic kidney disease: role of inflammation, proteinuria, hypertension, and diabetes mellitus

  2018cites this paper
• The and role and

  2018cites this paper
• Inflammation and Autonomic Function

  2018cites this paper
• Nicotinic acetylcholine receptor α7 subunit improves energy homeostasis and inhibits inflammation in nonalcoholic fatty liver disease.

  2018cites this paper
• Gut microbiota and inflammation in chronic kidney disease and their roles in the development of cardiovascular disease

  2018influential citation
• Different effects of global osteopontin and macrophage osteopontin in glomerular injury.

  2018cites this paper
• Activation of the cholinergic anti-inflammatory pathway by GTS-21 attenuates cisplatin-induced acute kidney injury in mice

  2017cites this paper
• N‐Stearoylethanolamine protects the brain and improves memory of mice treated with lipopolysaccharide or immunized with the extracellular domain of &agr;7 nicotinic acetylcholine receptor

  2017cites this paper
• Sodium ion transport participates in non-neuronal acetylcholine release in the renal cortex of anesthetized rabbits

  2017cites this paper
• Zingiberis Siccatum Rhizoma, the active component of the Kampo formula Daikenchuto, induces anti‐inflammatory actions through α7 nicotinic acetylcholine receptor activation

  2017cites this paper
• The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice.

  2016cites this paper
• Molecular Mechanisms Regulating LPS-Induced Inflammation in the Brain

  2016cites this paper
• Macrophage A2A Adenosine Receptors Are Essential to Protect from Progressive Kidney Injury.

  2016cites this paper
• The Role of α7 Nicotinic Acetylcholine Receptors and α7-Specific Antibodies in Neuroinflammation Related to Alzheimer Disease.

  2016cites this paper
• Autonomic nervous system activity and inflammation: good ideas, good treatments, or both?

  2015cites this paper
• Endogenous Inhibitors of Kidney Inflammation.

  2015cites this paper
• Manuscript Title: Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of immune-mediated kidney disease. Authors and Affiliations:

  year unknowncites this paper