Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  DNA Repair

• Publication date

  2011-01-02

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.dnarep.2010.09.005PMID 20961817PMCID PMC3065367
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• DNA polymerase beta-dependent long patch base excision repair in living cells.

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• Human DNA polymerase iota protects cells against oxidative stress

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• Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta.

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• Single-turnover Kinetic Analysis of the Mutagenic Potential of 8-Oxo-7,8-dihydro-2′-deoxyguanosine during Gap-filling Synthesis Catalyzed by Human DNA Polymerases λ and β

  2007cited by this paper
• Kinetic Effect of a Downstream Strand and Its 5′-Terminal Moieties on Single Nucleotide Gap-filling Synthesis Catalyzed by Human DNA Polymerase λ*

  2006cited by this paper
• Up-regulation of the Fidelity of Human DNA Polymerase λ by Its Non-enzymatic Proline-rich Domain*

  2006cited by this paper
• Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase.

  2006cited by this paper
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  2006cited by this paper
• Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain.

  2006cited by this paper
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  2006cited by this paper
• Comparison of functional properties of mammalian DNA polymerase λ and DNA polymerase β in reactions of DNA synthesis related to DNA repair

  2005cited by this paper
• DNA polymerase lambda protects mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage/repair.

  2005cited by this paper
• Structure-function studies of DNA polymerase lambda.

  2005cited by this paper
• DNA Polymerase λ Mediates a Back-up Base Excision Repair Activity in Extracts of Mouse Embryonic Fibroblasts*

  2005cited by this paper
• DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair.

  2005cited by this paper
• Comparison of functional properties of mammalian DNA polymerase lambda and DNA polymerase beta in reactions of DNA synthesis related to DNA repair.

  2005cited by this paper
• DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts.

  2005cited by this paper
• A closed conformation for the Pol lambda catalytic cycle.

  2005cited by this paper
• DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex.

  2004cited by this paper
• A Structural Solution for the DNA Polymerase λ-Dependent Repair of DNA Gaps with Minimal Homology

  2004cited by this paper
• A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology.

  2004cited by this paper
• Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells.

  2004cited by this paper
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  2004cited by this paper
• The Frameshift Infidelity of Human DNA Polymerase λ

  2003cited by this paper
• Localization of the Deoxyribose Phosphate Lyase Active Site in Human DNA Polymerase ι by Controlled Proteolysis*

  2003cited by this paper
• Over‐expression of human DNA polymerase lambda in E. coli and characterization of the recombinant enzyme

  2002cited by this paper
• Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage.

  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
• Two novel human and mouse DNA polymerases of the polX family.

  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• The Fidelity of DNA Polymerase β during Distributive and Processive DNA Synthesis*

  1999cited by this paper
• Quality control by DNA repair.

  1999cited by this paper
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  1998cited by this paper
• Mammalian base excision repair by DNA polymerases δ and ε

  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• DNA polymerase β : effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes1

  1998cited by this paper
• Second pathway for completion of human DNA base excision‐repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

  1997cited by this paper
• Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.

  1997cited by this paper
• Increased Activity and Fidelity of DNA Polymerase β on Single-nucleotide Gapped DNA*

  1997cited by this paper
• Requirement of mammalian DNA polymerase-beta in base-excision repair.

  1996cited by this paper
• Characterization of the DNA polymerase requirement of human base excision repair.

  1996cited by this paper
• Two Pathways for Base Excision Repair in Mammalian Cells (*)

  1996influential reference
• DNA Polymerase Conducts the Gap-filling Step in Uracil-initiated Base Excision Repair in a Bovine Testis Nuclear Extract (*)

  1995cited by this paper
• Short gap-filling synthesis by DNA polymerase beta is processive.

  1993cited by this paper
• DNA Polymerase (cid:1) and Flap Endonuclease 1 Enzymatic Specificities Sustain DNA Synthesis for Long Patch Base Excision Repair*

  year unknowncited by this paper
• DNA Polymerase (cid:1) Protects Mouse Fibroblasts against Oxidative DNA Damage and Is Recruited to Sites of DNA Damage/Repair*

  year unknowncited by this paper

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