Development and characterisation of levosulpiride-loaded suppositories with improved bioavailability in vivo

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Pharmaceutical development and technology (Print)

• Publication date

  2019-01-02

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1080/10837450.2017.1419256PMID 29251521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Irinotecan-loaded double-reversible thermogel with improved antitumor efficacy without initial burst effect and toxicity for intramuscular administration.

  2017cited by this paper
• Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration

  2017cited by this paper
• Development of a novel l-sulpiride-loaded quaternary microcapsule: Effect of TPGS as an absorption enhancer on physicochemical characterization and oral bioavailability.

  2016influential reference
• Comparison of solvent-wetted and kneaded l-sulpiride-loaded solid dispersions: Powder characterization and in vivo evaluation.

  2016influential reference
• Novel dual-reverse thermosensitive solid lipid nanoparticle-loaded hydrogel for rectal administration of flurbiprofen with improved bioavailability and reduced initial burst effect.

  2015influential reference
• Development of a novel solid lipid nanoparticles-loaded dual-reverse thermosensitive nanomicelle for intramuscular administration with sustained release and reduced toxicity

  2015influential reference
• Docetaxel-Loaded Thermosensitive and Bioadhesive Nanomicelles as a Rectal Drug Delivery System for Enhanced Chemotherapeutic Effect

  2013influential reference
• Novel sulpiride-loaded solid lipid nanoparticles with enhanced intestinal permeability

  2013cited by this paper
• Docetaxel-loaded thermosensitive liquid suppository: optimization of rheological properties

  2013influential reference
• Thermosensitive and mucoadhesive in situ gel based on poloxamer as new carrier for rectal administration of nimesulide.

  2012cited by this paper
• In vitro biocompatibility of thermally gelling liquid mucoadhesive loaded curcuminoids in colorectal cancer chemoprevention

  2012cited by this paper
• Development of thermo-sensitive injectable hydrogel with sustained release of doxorubicin: Rheological characterization and in vivo evaluation in rats

  2011influential reference
• Mucoadhesive drug delivery systems

  2011cited by this paper
• Injectable thermally responsive mucoadhesive gel for sustained protein delivery.

  2011cited by this paper
• Levosulpiride in premature ejaculation.

  2010cited by this paper
• Formulation and in vitro characterization of an in situ gelable, photo-polymerizable Pluronic hydrogel suitable for injection.

  2007cited by this paper
• Development of a Thermogelling Ophthalmic Formulation of Cysteine

  2006cited by this paper
• Canine versus in vitro data for predicting input profiles of L-sulpiride after oral administration.

  2005cited by this paper
• PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release.

  2005cited by this paper
• The basics and underlying mechanisms of mucoadhesion.

  2005cited by this paper
• Preparation of ibuprofen-loaded liquid suppository using eutectic mixture system with menthol.

  2004cited by this paper
• Temporary vascular occlusion with poloxamer 407.

  2004cited by this paper
• Levosulpiride: a new solution for premature ejaculation?

  2002cited by this paper
• Poloxamer 407 as a Thermogelling and Adhesive Polymer for Rectal Administration of Short-Chain Fatty Acids

  2001cited by this paper
• Effect of sodium chloride on the gelation temperature, gel strength and bioadhesive force of poloxamer gels containing diclofenac sodium.

  2001cited by this paper
• Effect of additives on the physicochemical properties of liquid suppository bases.

  1999cited by this paper
• Controlled release of vancomycin from poloxamer 407 gels.

  1999influential reference
• Bioadhesive Drug Delivery Systems : Fundamentals, Novel Approaches, and Development

  1999cited by this paper
• Development of in situ-gelling and mucoadhesive acetaminophen liquid suppository

  1998influential reference
• In situ gelling and mucoadhesive liquid suppository containing acetaminophen : Enhanced bioavailability

  1998influential reference
• Thermally reversible xyloglucan gels as vehicles for rectal drug delivery.

  1998cited by this paper
• Mucoadhesive Drug Delivery Systems

  1997cited by this paper

• Formulation and in vitro, in vivo characterizations of colchicine loaded nanoemulsion for gout management

  2026cites this paper
• Improved wound care via novel dextran and boric acid loaded wound healing gel in excision mice wound model

  2025cites this paper
• Development of novel electrospun nanofibers loaded with Levosulpiride and Cannabidiol encapsulated in cyclodextrin-phospholipid inclusion complex for ameliorated treatment of anxiety and depression.

  2025cites this paper
• Improved biopharmaceutical performance of chlorpromazine-nanostructured lipid carriers: In vitro release, pharmacokinetics and toxicity testing

  2025cites this paper
• A Bibliometric Analysis and Systematic Review of Research Advances in In Situ Gel Drug Delivery Systems from 2003 to 2023

  2025cites this paper
• A thermoresponsive system of niclosamide for colon specific delivery in ulcerative colitis: Bioavailability and safety investigation

  2025cites this paper
• Injectable dual thermoreversible hydrogel for sustained intramuscular drug delivery.

  2024cites this paper
• Thermoresponsive biomaterial system of irinotecan and curcumin for the treatment of colorectal cancer: in-vitro and in-vivo investigations

  2024cites this paper
• Nanostructured lipid carriers as a strategy to enhance oral levosulpiride delivery: An in vitro and ex vivo assessment.

  2024cites this paper
• Formulating an Innovative Emulsion Based on Poloxamer 407 Containing Oregano and Thyme Essential Oils as Alternatives for the Control of Mastitis Caused by Staphylococcus aureus

  2024cites this paper
• Development and validation of a reversed-phase HPLC-UV method for simultaneous determination of levosulpiride and omeprazole in human plasma: Applicability of the method for evaluation of pharmacokinetic drug-drug interactions

  2024cites this paper
• In situ gels: The next new frontier in ophthalmic drug delivery system

  2023cites this paper
• Development and evaluation of regorafenib loaded liquid suppository for rectal delivery: In vitro, in vivo analyses

  2023cites this paper
• Quality by design for sumatriptan loaded nano-ethosomal mucoadhesive gel for the therapeutic management of nitroglycerin induced migraine.

  2023cites this paper
• Micellar Encapsulation of Propofol Reduces its Adsorption on Extracorporeal Membrane Oxygenator (ECMO) Circuit

  2023cites this paper
• Co-delivery of trifluralin and miltefosin with enhanced skin penetration and localization in Leishmania affected macrophages

  2023cites this paper
• Levosulpiride-loaded nanostructured lipid carriers for brain delivery with antipsychotic and antidepressant effects.

  2022cites this paper
• Designing, optimization and characterization of Trifluralin transfersomal gel to passively target cutaneous leishmaniasis.

  2022cites this paper
• Development and characterization of a novel mucoadhesive sol-gel suppository of sumatriptan: design, optimization, in vitro and ex vivo evaluation for rectal drug delivery.

  2022cites this paper
• Formulation of oxybutynin chloride microparticle-loaded suppositories: in vitro characterization and in vivo pharmacokinetic study

  2022cites this paper
• Rectal administration of Celecoxib liquid suppositories with enhanced bioavailability and safety in rats.

  2022cites this paper
• Recent advances in wearable medical diagnostic sensors and new therapeutic dosage forms for fever in children.

  2022cites this paper
• A cutback in Imiquimod cutaneous toxicity; comparative cutaneous toxicity analysis of Imiquimod nanotransethosomal gel with 5% marketed cream on the BALB/c mice

  2022cites this paper
• Novel Curcumin-Encapsulated α-Tocopherol Nanoemulsion System and Its Potential Application for Wound Healing in Diabetic Animals

  2022cites this paper
• Improved biopharmaceutical performance of antipsychotic drug using lipid nanoparticles via intraperitoneal route

  2022cites this paper
• Particle and Gel Characterization of Irinotecan-Loaded Double-Reverse Thermosensitive Hydrogel

  2021cites this paper
• Fluconazole-loaded thermosensitive system: In vitro release, pharmacokinetics and safety study

  2021cites this paper
• Preparation, characterizations and in vitro evaluation of Econazole-Betamethasone loaded solid lipid nanoparticles (SLNs)

  2021cites this paper
• Intranasal delivery of Clozapine using nanoemulsion-based in-situ gels: An approach for bioavailability enhancement

  2021cites this paper
• Chitosan (Poly-(D) glucosamine) based solid lipid nanoparticles of dexibuprofen for topical delivery: Formulation development and characterizations

  2021cites this paper
• Pre‐clinical and clinical applications of thermoreversible hydrogels in biomedical engineering: a review

  2021cites this paper
• Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery

  2021cites this paper
• Topotecan-loaded thermosensitive nanocargo for tumor therapy: In vitro and in vivo analyses.

  2021cites this paper
• Achievements in Thermosensitive Gelling Systems for Rectal Administration

  2021influential citation
• Fabrication of a Thermosensitive In Situ Gel Nanoemulsion for Nose to Brain Delivery of Temozolomide

  2021cites this paper
• Preparation, in-vitro and in-vivo evaluation of Rifampicin and Vancomycin Co-loaded transfersomal gel for the treatment of cutaneous leishmaniasis

  2020cites this paper
• Development of levosulpiride-loaded solid lipid nanoparticles and their in vitro and in vivo comparison with commercial product

  2020cites this paper
• Polyethylene glycol (5,000) succinate conjugate of lopinavir and its associated toxicity using Danio rerio as a model organism

  2020cites this paper
• Development, In vitro and In vivo Evaluation of Miltefosine Loaded Nanostructured Lipid Carriers for the Treatment of Cutaneous Leishmaniasis.

  2020cites this paper
• GSK3 inhibitor-loaded osteotropic Pluronic hydrogel effectively mitigates periodontal tissue damage associated with experimental periodontitis.

  2020cites this paper
• The Gut Microbiome and Treatment-Resistance in Schizophrenia

  2019cites this paper
• Physiological and Pharmaceutical Considerations for Rectal Drug Formulations

  2019cites this paper
• Tolmetin sodium-loaded thermosensitive mucoadhesive liquid suppositories for rectal delivery; strategy to overcome oral delivery drawbacks

  2018cites this paper
• Mucosal Applications of Poloxamer 407-Based Hydrogels: An Overview

  2018influential citation