Deletion of the Cl-/HCO3- exchanger pendrin downregulates calcium-absorbing proteins in the kidney and causes calcium wasting.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Nephrology, Dialysis and Transplantation

• Publication date

  2012-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/ndt/gfr505PMID 21873623PMCID PMC3315671
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nephrolithiasis-associated bone disease: pathogenesis and treatment options.

  2011cited by this paper
• The renal connecting tubule: Resolved and unresolved issues in Ca(2+) transport.

  2011cited by this paper
• Deletion of the anion exchanger Slc26a4 (pendrin) decreases apical Cl(-)/HCO3(-) exchanger activity and impairs bicarbonate secretion in kidney collecting duct.

  2010cited by this paper
• Clinical practice. Calcium kidney stones.

  2010cited by this paper
• Testosterone increases urinary calcium excretion and inhibits expression of renal calcium transport proteins.

  2010cited by this paper
• Evidence for altered renal tubule function in idiopathic calcium stone formers

  2010cited by this paper
• Calcium Oxalate Stone Formation in the Inner Ear as a Result of an Slc26a4 Mutation*♦

  2010cited by this paper
• Slc26a9—Anion Exchanger, Channel and Na+ Transporter

  2009cited by this paper
• Deletion of the Chloride Transporter Slc26a7 Causes Distal Renal Tubular Acidosis and Impairs Gastric Acid Secretion*

  2009cited by this paper
• Species differences in Cl− affinity and in electrogenicity of SLC26A6‐mediated oxalate/Cl− exchange correlate with the distinct human and mouse susceptibilities to nephrolithiasis

  2008cited by this paper
• Mechanism of urinary calcium regulation by urinary magnesium and pH.

  2008cited by this paper
• Deletion of the chloride transporter Slc26a9 causes loss of tubulovesicles in parietal cells and impairs acid secretion in the stomach

  2008cited by this paper
• Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

  2007cited by this paper
• TRPV5, the gateway to Ca2+ homeostasis.

  2007cited by this paper
• SLC26 chloride/base exchangers in the kidney in health and disease.

  2006cited by this paper
• Dietary Cl(-) restriction upregulates pendrin expression within the apical plasma membrane of type B intercalated cells.

  2006cited by this paper
• Acid-base status determines the renal expression of Ca2+ and Mg2+ transport proteins.

  2006cited by this paper
• slc26a3 (dra)-deficient Mice Display Chloride-losing Diarrhea, Enhanced Colonic Proliferation, and Distinct Up-regulation of Ion Transporters in the Colon*

  2006cited by this paper
• Critical role of the epithelial Ca2+ channel TRPV5 in active Ca2+ reabsorption as revealed by TRPV5/calbindin-D28K knockout mice.

  2006cited by this paper
• Physiology of electrogenic SLC26 paralogues.

  2006cited by this paper
• Cystine calculi: challenging group of stones

  2006cited by this paper
• Calcium oxalate urolithiasis in mice lacking anion transporter Slc26a6

  2006cited by this paper
• SLC26A7 Is a Cl– Channel Regulated by Intracellular pH*

  2005cited by this paper
• Calcium absorption across epithelia.

  2005cited by this paper
• Renal and intestinal transport defects in Slc26a6-null mice.

  2005cited by this paper
• The Cl-/HCO3- exchanger pendrin in the rat kidney is regulated in response to chronic alterations in chloride balance.

  2004cited by this paper
• Regulation of the apical Cl-/HCO-3 exchanger pendrin in rat cortical collecting duct in metabolic acidosis.

  2003cited by this paper
• Mineralocorticoid-induced Hypertension ) in Mouse Kidney : Role of Pendrin in Slc26a4 ( Pds Deoxycorticosterone Upregulates

  2003cited by this paper
• Localization of pendrin in mouse kidney.

  2003cited by this paper
• Regulated expression of pendrin in rat kidney in response to chronic NH4Cl or NaHCO3 loading.

  2003cited by this paper
• Molecular and functional characterization of SLC26A11, a sodium‐independent sulfate transporter from high endothelial venules

  2003cited by this paper
• Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells.

  2003cited by this paper
• Pathophysiologic basis for normouricosuric uric acid nephrolithiasis.

  2002cited by this paper
• Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1.

  2002cited by this paper
• Immunocytochemical localization of pendrin in intercalated cell subtypes in rat and mouse kidney.

  2002cited by this paper
• Identification of an apical Cl(-)/HCO3(-) exchanger in the small intestine.

  2002cited by this paper
• Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status.

  2002cited by this paper
• Molecular mechanism of active Ca2+ reabsorption in the distal nephron.

  2002cited by this paper
• Functional Characterization of Three Novel Tissue-specific Anion Exchangers SLC26A7, -A8, and -A9*

  2002cited by this paper
• Paracellin-1 is critical for magnesium and calcium reabsorption in the human thick ascending limb of Henle.

  2001cited by this paper
• Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron.

  2001cited by this paper
• Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells

  2001cited by this paper
• Biochemical profile of idiopathic uric acid nephrolithiasis.

  2001cited by this paper
• Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex.

  2001cited by this paper
• Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion

  2001cited by this paper
• Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.

  2000cited by this paper
• Localization of the epithelial Ca(2+) channel in rabbit kidney and intestine.

  2000cited by this paper
• Prestin is the motor protein of cochlear outer hair cells

  2000cited by this paper
• Mouse Down-regulated in Adenoma (DRA) Is an Intestinal Cl−/HCO3 − Exchanger and Is Up-regulated in Colon of Mice Lacking the NHE3 Na+/H+Exchanger*

  1999cited by this paper
• Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)

  1997cited by this paper
• Mutations of the Down–regulated in adenoma (DRA) gene cause congenital chloride diarrhoea

  1996cited by this paper
• Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes.

  1994cited by this paper
• The diastrophic dysplasia gene encodes a novel sulfate transporter: positional cloning by fine-structure linkage disequilibrium mapping.

  1994cited by this paper
• Prophylaxis of uric acid stones with alternate day doses of alkaline potassium salts.

  1991cited by this paper

• Prospective associations between the CKD-mineral bone disorder and metabolic acidosis.

  2025cites this paper
• Deciphering the function of the fifth class of Gα proteins: regulation of ionic homeostasis as unifying hypothesis

  2024cites this paper
• OXGR1 is a candidate disease gene for human calcium oxalate nephrolithiasis.

  2022cites this paper
• Regulation of urinary calcium excretion by vasopressin

  2020cites this paper
• OP-NDTP200137 873..877

  2020cites this paper
• Importance of SLC26 Transmembrane Anion Exchangers in Sperm Post-testicular Maturation and Fertilization Potential

  2019cites this paper
• The non-diuretic hypotensive effects of thiazides are enhanced during volume depletion states

  2017cites this paper
• Acid Load and Phosphorus Homeostasis in CKD.

  2017cites this paper
• Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model of Distal Nephron Salt Wasting

  2016cites this paper
• The multiple roles of pendrin in the kidney.

  2015cites this paper
• Distal convoluted tubule.

  2015cites this paper
• Comparative Evaluation of the Gastroprotective Effect of L-Carnitine and Omeprazole on Ethanol-Induced Gastric Ulcer in Male Albino Wister Rats

  2014cites this paper
• Bicarbonate transport in health and disease

  2014cites this paper
• Molecular mechanisms and regulation of urinary acidification.

  2014cites this paper
• The role of drug transporters in the kidney: lessons from tenofovir

  2014cites this paper
• SLC26 Cl−/HCO3− Exchangers in the Kidney: Roles in Health and Disease

  2013cites this paper
• The SLC26 gene family of anion transporters and channels.

  2013cites this paper
• The Role of Pendrin in the Development of the Murine Inner Ear

  2011cites this paper
• Integration of Human and Mouse Genetics Reveals Pendrin Function in Hearing and Deafness

  2011cites this paper