The Leeuwenhoek Lecture, 1978 Bacteria as proper subjects for cancer research

No abstract is available for this paper.

• Publication year

  1980

• Venue

  Proceedings of the Royal Society of London. Series B. Biological Sciences

• Publication date

  1980-06-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1098/rspb.1980.0046PMID 6105653
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quantitation of the adaptive response to alkylating agents

  1979cited by this paper
• Volatile N-nitrosamines in the urine of normal donors and of bladder cancer patients.

  1979cited by this paper
• Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents

  1979cited by this paper
• Increased excision of O6-methylguanine from rat liver DNA after chronic administration of dimethylnitrosamine.

  1979cited by this paper
• Molecular events and molecules that lead to induction of prophage and SOS functions.

  1979cited by this paper
• DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by O(6)-methylguanine.

  1979cited by this paper
• Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

  1979cited by this paper
• An Adaptive Response of E.coli to Low Levels of Alkylating Agent

  1978cited by this paper
• Dimethylnitrosamine inhibits enzymatic removal of O6-methylguanine from DNA

  1978cited by this paper
• Estimate of the volatile nitrosamine content of UK food

  1978cited by this paper
• Volatile nitrosamines in normal human faeces

  1978cited by this paper
• Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents

  1978cited by this paper
• Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens.

  1978cited by this paper
• Repair of O6-methylguanine in adapted Escherichia coli.

  1978cited by this paper
• The segregation of DNA in epithelial stem cells.

  1978cited by this paper
• The adaptive response of E. coli to low levels of alkylating agent: The role of polA in killing adaptation

  1978cited by this paper
• LA TECHNIQUE DE CULTURE CONTINUE THÉORIE ET APPLICATIONS

  1978cited by this paper
• An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

  1977cited by this paper
• A new pathway for DNA repair in Escherichia coli

  1977cited by this paper
• Formation in vivo of volatile N-nitrosamines in man after ingestion of cooked bacon and spinach

  1977cited by this paper
• Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli.

  1977cited by this paper
• Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine.

  1977cited by this paper
• Carcinogenicity of N-nitrosopyrrolidine: Dose-response study in rats

  1977cited by this paper
• Exhaustion and recovery of repair excision of O6-methylguanine from rat liver DNA

  1976cited by this paper
• Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

  1976cited by this paper
• Possible repair of carcinogenic damage caused by dimethylnitrosamine in rat kidney

  1976cited by this paper
• All oxygens in nucleic acids react with carcinogenic ethylating agents

  1976cited by this paper
• Chemical carcinogenesis in the nervous system. Preferential accumulation of O6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of N-methyl-N-nitrosourea.

  1975cited by this paper
• Molecular mechanisms in alkylation mutagenesis. Induced reversion of bacteriophage T4rII AP72 by ethyl methanesulphonate in relation to extent and mode of ethylation of purines in bacteriophage deoxyribonucleic acid.

  1975cited by this paper
• Normal genetically mosaic mice produced from malignant teratocarcinoma cells.

  1975cited by this paper
• Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

  1975cited by this paper
• Mutagenesis by nitrosoguanidine, ethyl methanesulfonate, and mutator gene mutH in continuous cultures of Escherichia coli.

  1975cited by this paper
• Fate of teratocarcinoma cells injected into early mouse embryos

  1975cited by this paper
• Mutation selection and the natural history of cancer

  1975cited by this paper
• THE EFFECT OF CELLS TRANSFERRED INTO THE MOUSE BLASTOCYST ON SUBSEQUENT DEVELOPMENT

  1974cited by this paper
• Persistence of O6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea.

  1974cited by this paper
• Correlation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian species.

  1974cited by this paper
• The properties of O 6 -methylguanine in templates for RNA polymerase.

  1973cited by this paper
• Comparative Studies of the Hepatocarcinogen N,N-Dimethylnitrosamine in vivo: Reaction Sites in Rat Liver DNA and the Significance of their Relative Stabilities

  1973cited by this paper
• Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.

  1973cited by this paper
• The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos.

  1970cited by this paper
• Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N'-nitro-N-nitrosoguanidine.

  1970cited by this paper
• Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation.

  1970cited by this paper
• THE MUTAGENICITY AND INITIATING ACTIVITY OF SOME AROMATIC AMINE METABOLITES *

  1969cited by this paper
• Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

  1969cited by this paper
• A Host-Mediated Microbial Assay for the Detection of Mutagenic Compounds

  1969cited by this paper
• Hepatic pathology in rats on low dietary levels of dimethylnitrosamine.

  1967cited by this paper
• HOW MANY CELL-GENERATIONS?

  1965cited by this paper
• MUTATION IN CONTINUOUS CULTURES. II. MUTATIONS INDUCED WITH ULTRAVIOLET LIGHT AND 2-AMINOPURINE.

  1964cited by this paper
• Induction of Bacteriophage Formation in Lysogenic Bacteria by a Potent Carcinogen, 4-Nitroquinoline l-oxide, and its Derivatives

  1963cited by this paper
• BACTERIAL SYNCHRONIZATION BY SELECTION OF CELLS AT DIVISION.

  1963cited by this paper
• N-Hydroxy-2-acetylaminofluorene: a metabolite of 2-acetylaminofluorene with increased carcinogenic activity in the rat.

  1961cited by this paper
• Mutagens and antimutagens.

  1956cited by this paper
• MUTATION RATES OF BACTERIA IN STEADY STATE POPULATIONS

  1955cited by this paper
• Periodic selection in Escherichia coli.

  1951cited by this paper
• Experiments with the Chemostat on spontaneous mutations of bacteria.

  1950cited by this paper
• Measurements of rate of mutation of flagellar antigenic phase in Salmonella typhi-murium

  1949cited by this paper
• Chemical Carcinogenesis and Experimental Chemotherapy of Cancer *

  1948cited by this paper
• Neoplastic transformation of granulosa cells in grafts of normal ovaries into spleens of gonadectomized mice.

  1947cited by this paper
• A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin

  1947cited by this paper
• THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION

  1944cited by this paper

• Dietary-induced cancer prevention: An expanding research arena of emerging diet related to healthcare system

  2012cites this paper
• Models of carcinogenesis: an overview.

  2010cites this paper
• Converging concepts: adaptive response, preconditioning, and the Yerkes-Dodson Law are manifestations of hormesis.

  2008cites this paper
• Wound Healing and Skin Substitutes

  2006cites this paper
• A review of DNA metabolism in Escherichia coli.

  1991cites this paper
• New DNA Repair Systems and New Insights on Old Systems in Escherichia coli

  1986cites this paper
• Studies of the repair of O6-alkylguanine and O4-alkylthymine in DNA by alkyltransferases from mammalian cells and bacteria.

  1985cites this paper
• Relevance of nitrosamines to human cancer.

  1984cites this paper
• Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli.

  1984cites this paper
• O6-alkylguanine-DNA alkyltransferase activity in human brain and brain tumors.

  1984cites this paper
• Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.

  1984cites this paper
• Introduction: DNA damage and repair.

  1983cites this paper
• Removal of O6-methylguanine from DNA by human liver fractions.

  1982cites this paper
• [Molecular mechanisms of adaptation of cells to low levels of carcinogenic agents (author's transl)].

  1982cites this paper
• The inducible repair of alkylated DNA.

  1981cites this paper
• Enzymatic synthesis of double-stranded DNA containing radioactively labeled O(6)-ethylguanine as the only modified base.

  1981cites this paper
• Alkylation of DNA and tissue specificity in nitrosamine carcinogenesis.

  1981cites this paper