Multimodality MR Imaging Findings of Low-Grade Brain Edema in Hepatic Encephalopathy

SUMMARY: HE is a neuropsychiatric syndrome that develops in patients with severe liver diseases, with portosystemic shunt surgery in the form of diffuse mild brain edema. It is also associated with functional changes, such as those in attention and the DMN. MR imaging offers a range of capabilities for assessing the low-grade brain edema and its functional changes in brain affected by HE; therefore, it provides the opportunity to uncover the pathophysiologic mechanisms of HE. This article will review our current understanding of the pathophysiology of low-grade brain edema and will outline the role of structural MR imaging, MTR, DWI, DTI, and MR spectroscopy in the detection of low-grade brain edema, and the role of BOLD fMRI in the exploration of the related functional changes. A perspective of the study in this area will also be provided.

• Publication year

  2013

• Venue

  American Journal of Neuroradiology

• Publication date

  2013-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.3174/ajnr.A2968PMID 22383235PMCID PMC7964470
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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