Caveolin-1: a marker for pancreatic cancer diagnosis

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Expert Review of Molecular Diagnostics

• Publication date

  2008-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1586/14737159.8.4.395PMID 18598222
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Caveolin-1: A tumor-promoting role in human cancer

  2008cited by this paper
• CA 19-9 tumour-marker response to chemotherapy in patients with advanced pancreatic cancer enrolled in a randomised controlled trial.

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• TPS, CA 19-9, VEGF-A, and CEA as Diagnostic and Prognostic Factors in Patients with Mass Lesions in the Pancreatic Head

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• Caveolae/caveolin-1 are important modulators of store-operated calcium entry in Hs578/T breast cancer cells.

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• Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis

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• Protein profiling of microdissected pancreas carcinoma and identification of HSP27 as a potential serum marker.

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• The Ras-MAPK pathway downregulates Caveolin-1 in rodent fibroblast but not in human fibroblasts: implications in the resistance to oncogene-mediated transformation

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• Caveolin-1 Expression is Variably Displayed in Astroglial-derived Tumors and Absent in Oligodendrogliomas: Concrete Premises for a New Reliable Diagnostic Marker in Gliomas

  2007cited by this paper
• Combined detection of serum tumor markers for differential diagnosis of solid lesions located at the pancreatic head.

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• Over‐expression of S100A2 in pancreatic cancer correlates with progression and poor prognosis

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• Evaluation of clinical relevance of examining K-ras, p16 and p53 mutations along with allelic losses at 9p and 18q in EUS-guided fine needle aspiration samples of patients with chronic pancreatitis and pancreatic cancer.

  2007cited by this paper
• Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer.

  2007cited by this paper
• Differential expression and function of caveolin-1 in human gastric cancer progression.

  2007cited by this paper
• Preoperative serum carcinoembryonic antigen and carbohydrate antigen 19-9 levels for the evaluation of curability and resectability in patients with pancreatic adenocarcinoma.

  2007cited by this paper
• Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis.

  2007cited by this paper
• Differential expression of caveolin‐1 in renal neoplasms

  2007cited by this paper
• Molecular prognostic factors in patients with pancreatic cancer

  2007cited by this paper
• Effects of Vascular Endothelial Growth Factor on the Lymphocyte-Endothelium Interactions: Identification of Caveolin-1 and Nitric Oxide as Control Points of Endothelial Cell Anergy1

  2007cited by this paper
• Early detection and biomarkers in pancreatic cancer.

  2007cited by this paper
• Caveolin-1 expression in benign and malignant lesions of the breast

  2007cited by this paper
• Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1

  2007cited by this paper
• Cancer Statistics, 2006

  2006cited by this paper
• Caveolin-1 in meningiomas: expression and clinico-pathological correlations

  2006cited by this paper
• Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin

  2006cited by this paper
• Caveolin-1 as a potential new therapeutic target in multiple myeloma.

  2006cited by this paper
• Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?

  2006cited by this paper
• Is caveolin-1 a viable therapeutic target to reduce cancer metastasis?

  2006cited by this paper
• Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling

  2005cited by this paper
• Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells

  2005cited by this paper
• Expression of Ki-67, p53, and K-ras in chronic pancreatitis and pancreatic ductal adenocarcinoma.

  2005cited by this paper
• Antitumor effects of in vivo caveolin gene delivery are associated with the inhibition of the proangiogenic and vasodilatory effects of nitric oxide

  2005cited by this paper
• [Down-regulation of caveolin-1 in gastric carcinoma and its clinical biological significance].

  2005cited by this paper
• Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and Caveolin-1

  2005cited by this paper
• Caveolin-1 in oncogenic transformation, cancer, and metastasis.

  2005cited by this paper
• Caveolin-1 and 14-3-3 sigma expression in follicular variant of thyroid papillary carcinoma.

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• Caveolin‐1 is down‐regulated and inversely correlated with HER2 and EGFR expression status in invasive ductal carcinoma of the breast

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• Expression of caveolin-1 in pleomorphic carcinoma of the lung is correlated with a poor prognosis.

  2005cited by this paper
• Tumor M2-Pyruvate Kinase, a New Metabolic Marker for Pancreatic Cancer

  2004cited by this paper
• Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines.

  2004cited by this paper
• Promoter CpG methylation of caveolin-1 in sporadic colorectal cancer.

  2004cited by this paper
• CEACAM6 Cross-linking Induces Caveolin-1-dependent, Src-mediated Focal Adhesion Kinase Phosphorylation in BxPC3 Pancreatic Adenocarcinoma Cells*

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• Caveolins: structure and function in signal transduction.

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• The expression of Rho proteins decreases with human brain tumor progression: Potential tumor markers

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  2004cited by this paper
• Expression of caveolin-1 in gastrointestinal and extraintestinal cancers

  2003cited by this paper
• Comparison of tumor M2-pyruvate kinase (tumor M2-PK), carcinoembryonic antigen (CEA), carbohydrate antigens CA 19-9 and CA 72-4 in the diagnosis of gastrointestinal cancer.

  2003cited by this paper
• Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer.

  2003cited by this paper
• Caveolin-I overexpression is a favourable prognostic factor for patients with extrahepatic bile duct carcinoma.

  2003cited by this paper
• Caveolin-Induced Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Increases Arsenite Cytotoxicity

  2003cited by this paper
• Expression of caveolin-1 and caveolin-2 in urothelial carcinoma of the urinary bladder correlates with tumor grade and squamous differentiation.

  2003cited by this paper
• Caveolin-1 Maintains Activated Akt in Prostate CancerCells through Scaffolding Domain Binding Site Interactions with andInhibition of Serine/Threonine Protein Phosphatases PP1 andPP2A

  2003cited by this paper
• Peroxisome proliferator-activated receptor-γ upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells

  2003cited by this paper
• Peroxisome proliferator-activated receptor-gamma upregulates caveolin-1 and caveolin-2 expression in human carcinoma cells.

  2003cited by this paper
• Analysis of Ki-67 antigen expression, DNA proliferative fraction, and survival in resected cancer of the pancreas.

  2003cited by this paper
• Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation.

  2003cited by this paper
• Therapeutic targets for metastatic prostate cancer.

  2003cited by this paper
• Expression of caveolin-1 is associated with poor prognosis of patients with squamous cell carcinoma of the lung.

  2003cited by this paper
• Multiple Functions of Caveolin-1*

  2002cited by this paper
• Caveolin-1-mediated post-transcriptional regulation of inducible nitric oxide synthase in human colon carcinoma cells.

  2002cited by this paper
• Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation.

  2002cited by this paper
• Overexpression of caveolin‐1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage

  2002cited by this paper
• Caveolin-1 overexpression is an early event in the progression of papillary carcinoma of the thyroid

  2002cited by this paper
• Src-induced Phosphorylation of Caveolin-2 on Tyrosine 19

  2002cited by this paper
• Expression profiling of microdissected pancreatic adenocarcinomas

  2002cited by this paper
• Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas.

  2002cited by this paper
• Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma

  2002cited by this paper
• Profiling of differentially expressed cancer-related genes in esophageal squamous cell carcinoma (ESCC) using human cancer cDNA arrays: overexpression of oncogene MET correlates with tumor differentiation in ESCC.

  2001cited by this paper
• Hypermethylation of the caveolin‐1 gene promoter in prostate cancer

  2001cited by this paper
• Caveolin-1 Regulates Transforming Growth Factor (TGF)-β/SMAD Signaling through an Interaction with the TGF-β Type I Receptor*

  2001cited by this paper
• Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor.

  2001cited by this paper
• Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer.

  2001cited by this paper
• Elevated expression of caveolin-1 in adenocarcinoma of the colon.

  2001cited by this paper
• Invasion activating caveolin-1 mutation in human scirrhous breast cancers.

  2001cited by this paper
• Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas.

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• Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.

  2001cited by this paper
• Palmitoylation of Caveolin-1 at a Single Site (Cys-156) Controls Its Coupling to the c-Src Tyrosine Kinase

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• Distinction between signaling mechanisms in lipid rafts vs. caveolae

  2001cited by this paper
• Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

  2001cited by this paper
• Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene.

  2001cited by this paper
• Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle.

  2001cited by this paper
• A Molecular Dissection of Caveolin-1 Membrane Attachment and Oligomerization

  2000cited by this paper
• Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.

  2000cited by this paper
• Caveolin-1 Expression Inhibits Wnt/β-Catenin/Lef-1 Signaling by Recruiting β-Catenin to Caveolae Membrane Domains*

  2000cited by this paper
• Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.

  2000cited by this paper
• Caveolin 1-Mediated Regulation of Receptor Tyrosine Kinase-Associated Phosphatidylinositol 3-Kinase Activity by Ceramide

  2000cited by this paper
• Caveolin-1 Inhibits Epidermal Growth Factor-stimulated Lamellipod Extension and Cell Migration in Metastatic Mammary Adenocarcinoma Cells (MTLn3)

  2000cited by this paper
• The Cyclin D1 Gene Is Transcriptionally Repressed by Caveolin-1*

  2000cited by this paper
• Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity.

  2000cited by this paper
• Concomitant over‐expression of vascular endothelial growth factor and its receptors in pancreatic cancer

  2000cited by this paper
• Targeted downregulation of caveolin‐1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

  1998cited by this paper
• Interaction of a Receptor Tyrosine Kinase, EGF-R, with Caveolins

  1997cited by this paper
• Src Tyrosine Kinases, Gα Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin

  1996cited by this paper
• Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.

  1996cited by this paper
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• Is there any diagnostic value of serum caveolin-1 levels on the determination of pancreatic adenocarcinoma?

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• The different functions and clinical significances of caveolin-1 in human adenocarcinoma and squamous cell carcinoma

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• The Association Between Inflammation and Angiogenesis in Human Pancreatic Adenocarcinoma

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• Tagging Strategies Strongly Affect the Fate of Overexpressed Caveolin-1

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• The Dioxin receptor modulates Caveolin-1 mobilization during directional migration: role of cholesterol

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• Co-Regulation of Cell Polarization and Migration by Caveolar Proteins PTRF/Cavin-1 and Caveolin-1

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• Molecular and Cellular Pathobiology A Novel FoxM 1-Caveolin Signaling Pathway Promotes Pancreatic Cancer Invasion and Metastasis

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• Involvement of Caveolin-1 in Repair of DNA Damage through Both Homologous Recombination and Non-Homologous End Joining

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• Caveolin-1 expression in diffuse gliomas: correlation with the proliferation index, epidermal growth factor receptor, p53, and 1p/19q status.

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  2009cites this paper
• Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation.

  2009cites this paper
• Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma

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