The anterior cingulate cortex is a target structure for the anxiolytic-like effects of benzodiazepines assessed by repeated exposure to the elevated plus maze and Fos immunoreactivity.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Neuroscience

• Publication date

  2009-12-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/j.neuroscience.2009.08.038PMID 19699782
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Activity of the medial prefrontal cortex and amygdala underlies one-trial tolerance of rats in the elevated plus-maze.

  2008cited by this paper
• Pavlovian fear conditioning as a behavioral assay for hippocampus and amygdala function: cautions and caveats

  2008cited by this paper
• Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping.

  2007cited by this paper
• Increases in plasma corticosterone and stretched-attend postures in rats naive and previously exposed to the elevated plus-maze are sensitive to the anxiolytic-like effects of midazolam.

  2007cited by this paper
• When Fear Is Near: Threat Imminence Elicits Prefrontal-Periaqueductal Gray Shifts in Humans

  2007cited by this paper
• Inactivation of the ventromedial prefrontal cortex reduces expression of conditioned fear and impairs subsequent recall of extinction

  2006cited by this paper
• Distribution of Fos immunoreactivity in the rat brain after freezing or escape elicited by inhibition of glutamic acid decarboxylase or antagonism of GABA-A receptors in the inferior colliculus.

  2006cited by this paper
• Pharmacological assessment of the freezing, antinociception, and exploratory behavior organized in the ventrolateral periaqueductal gray

  2006cited by this paper
• Stress-Induced c-Fos Expression is Differentially Modulated by Dexamethasone, Diazepam and Imipramine

  2005cited by this paper
• Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test.

  2005cited by this paper
• Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on.

  2005cited by this paper
• “One-trial tolerance” to the anxiolytic actions of benzodiazepines in the elevated plus-maze, or the development of a phobic state?

  2005cited by this paper
• Trial 2 in the elevated plus-maze: a different form of fear?

  2005cited by this paper
• One-trial tolerance to the anxiolytic effects of chlordiazepoxide in the plus-maze

  2005cited by this paper
• A comparative study with two types of elevated plus-maze (transparent vs. opaque walls) on the anxiolytic effects of midazolam, one-trial tolerance and fear-induced analgesia.

  2005cited by this paper
• Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety

  2005cited by this paper
• Influence of prior maze experience on behaviour and response to diazepam in the elevated plus-maze and light/dark tests of anxiety in mice

  2005cited by this paper
• Stress-Induced c-Fos Expression is Differentially Modulated by Dexamethasone, Diazepam and Imipramine

  2005cited by this paper
• Infusions of midazolam into the medial prefrontal cortex produce anxiolytic effects in the elevated plus-maze and shock-probe burying tests.

  2004cited by this paper
• New vistas on amygdala networks in conditioned fear.

  2004cited by this paper
• The use of a plus-maze to measure anxiety in the mouse

  2004cited by this paper
• Effects of acute and chronic fluoxetine and diazepam on freezing behavior induced by electrical stimulation of dorsolateral and lateral columns of the periaqueductal gray matter.

  2004cited by this paper
• Neural Correlates of Cat Odor-Induced Anxiety in Rats: Region-Specific Effects of the Benzodiazepine Midazolam

  2004cited by this paper
• Medial septal lesions mimic effects of both selective dorsal and ventral hippocampal lesions.

  2004cited by this paper
• Dorsal premammillary nucleus differentially modulates defensive behaviors induced by different threat stimuli in rats.

  2003cited by this paper
• One-trial tolerance to midazolam is due to enhancement of fear and reduction of anxiolytic-sensitive behaviors in the elevated plus-maze retest in the rat.

  2002cited by this paper
• Behavioral profile of rats submitted to session 1-session 2 in the elevated plus-maze during diurnal/nocturnal phases and under different illumination conditions.

  2002cited by this paper
• The medial hypothalamic defensive system: hodological organization and functional implications.

  2002cited by this paper
• Activation of somatodendritic 5-HT(1A) autoreceptors in the median raphe nucleus disrupts the contextual conditioning in rats.

  2001cited by this paper
• Afferent connections of the dorsal premammillary nucleus

  2000cited by this paper
• Previous maze experience required to increase open arms avoidance in rats submitted to the elevated plus-maze model of anxiety.

  2000cited by this paper
• Lateralized Effects of Medial Prefrontal Cortex Lesions on Neuroendocrine and Autonomic Stress Responses in Rats

  1999cited by this paper
• The phenomenon of "one-trial tolerance" to the anxiolytic effect of chlordiazepoxide in the elevated plus-maze is abolished by the introduction of a motivational conflict situation.

  1999cited by this paper
• Role of the Dorsomedial Hypothalamus in Mediating the Response to Benzodiazepines on Trial 2 in the Elevated Plus-Maze Test of Anxiety

  1999cited by this paper
• Differential effects of post-training muscimol and AP5 infusions into different regions of the cingulate cortex on retention for inhibitory avoidance in rats.

  1999cited by this paper
• Ethopharmacological analysis of 5-HT ligands on the rat elevated plus-maze.

  1999cited by this paper
• Regulation of contextual conditioning by the median raphe nucleus.

  1998cited by this paper
• Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety

  1998cited by this paper
• Responses of Swiss-Webster mice to repeated plus-maze experience: further evidence for a qualitative shift in emotional state?

  1998cited by this paper
• Risk assessment behaviour: evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test.

  1997cited by this paper
• Dissociations among the anxiolytic effects of septal, hippocampal, and amygdaloid lesions.

  1997cited by this paper
• Severe reduction of rat defensive behavior to a predator by discrete hypothalamic chemical lesions.

  1997cited by this paper
• Prior exposure to a brief restraint session facilitates the occurrence of fear in response to a conflict situation: behavioral and neurochemical correlates.

  1997cited by this paper
• Ethopharmacological analysis of behaviour of rats using variations of the elevated plus-maze

  1997cited by this paper
• Differentiation of anxiolytic and panicolytic drugs by effects on rat and mouse defense test batteries.

  1997cited by this paper
• Serotonergic systems.

  1997cited by this paper
• Dissociations among the anxiolytic effects of septal, hippocampal, and amygdaloid lesions

  1997cited by this paper
• The effects of GABAA receptor blockade in the dorsomedial hypothalamic nucleus on corticotrophin (ACTH) and corticosterone secretion in male rats.

  1996cited by this paper
• A review of the validity and variability of the elevated plus-maze as an animal model of anxiety.

  1996cited by this paper
• Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos: with and without diazepam pretreatment

  1995cited by this paper
• Contributions of anterior cingulate cortex to behaviour.

  1995cited by this paper
• Chlordiazepoxide attenuates stress-induced activation of neurons, corticotropin-releasing factor (CRF) gene transcription and CRF biosynthesis in the paraventricular nucleus (PVN).

  1995cited by this paper
• Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety.

  1995cited by this paper
• Chlordiazepoxide microinjected into the region of the dorsal raphe nucleus eliminates the interference with escape responding produced by inescapable shock whether administered before inescapable shock or escape testing.

  1994cited by this paper
• Ethological evaluation of the effects of acute and chronic buspirone treatment in the murine elevated plus-maze test: comparison with haloperidol

  1994cited by this paper
• The interplay of learning and anxiety in the elevated plus-maze.

  1993cited by this paper
• Aversive and antiaversive effects of morphine in the dorsal periaqueductal gray of rats submitted to the elevated plus-maze test.

  1993cited by this paper
• A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry

  1993cited by this paper
• An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro 16–6028) in the murine elevated plus‐maze

  1993cited by this paper
• Defense system psychopharmacology: an ethological approach to the pharmacology of fear and anxiety.

  1993cited by this paper
• The effect of medial frontal cortex lesions on respiration, "freezing," and ultrasonic vocalizations during conditioned emotional responses in rats.

  1991cited by this paper
• Efferent projections of the infralimbic cortex of the rat

  1991cited by this paper
• Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract‐tracing study with Phaseolus vulgaris leucoagglutinin

  1989cited by this paper
• Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear

  1988cited by this paper
• The dorsomedial hypothalamic nucleus revisited: 1986 update.

  1987cited by this paper
• Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.

  1985cited by this paper
• The involvement of the anterior cingulate cortex in blood pressure control.

  1985cited by this paper
• Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis.

  1985cited by this paper
• Analysis of benzodiazepine binding sites in rat pituitary gland.

  1984cited by this paper
• Autoradiographic localisation of benzodiazepine receptors in the rat pituitary gland.

  1984cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
• Reciprocal connections between the lateral hypothalamus and the frontal complex in the rat: electrophysiological and anatomical observations.

  1981cited by this paper
• A direct projection from Ammon's horn to prefrontal cortex in the rat.

  1981cited by this paper
• Organization of ascending serotonin systems in the adult rat brain. A radioautographic study after intraventricular administration of [3H]5-hydroxytryptamine.

  1981cited by this paper
• Radiohistochemical localization of benzodiazepine receptors in rat brain.

  1980cited by this paper
• Single neuron analysis of the human midbrain tegmentum. Rostral mecencephalic reticulotomy for pain relief.

  1978cited by this paper
• Effects of electrical stimulation of the lateral aspect of the prefrontal cortex upon attack behavior in cats.

  1974cited by this paper
• Effects of electrical stimulation of the cingulate gyrus upon attack behavior elicited from the hypothalamus in the cat.

  1971cited by this paper
• Sensations evoked by stimulation in the midbrain of man.

  1969cited by this paper

• Research progress on the neural circuits mechanisms of anxiety

  2025cites this paper
• Differential modulation of the anterior cingulate and insular cortices on anxiogenic-like responses induced by empathy for pain.

  2020cites this paper
• Distinct patterns of brain Fos expression in Carioca High- and Low-conditioned Freezing Rats

  2020cites this paper
• Fecal transplant prevents gut dysbiosis and anxiety-like behaviour after spinal cord injury in rats

  2020cites this paper
• Effects of plus-maze experience and chlordiazepoxide on anxiety-like behavior and serotonin neural activity in the dorsal raphe nucleus in rats

  2019cites this paper
• Involvement of Serotonergic and Relaxin-3 Neuropeptide Systems in the Expression of Anxiety-like Behavior.

  2018cites this paper
• Repeated elevated plus maze trials as a measure for tracking within-subjects behavioral performance in rats (Rattus norvegicus)

  2018cites this paper
• Anxiolytic-like effect of hydrogen sulfide (H2S) in rats exposed and re-exposed to the elevated plus-maze and open field tests.

  2017influential citation
• Effect of diazepam and yohimbine on neuronal activity in sham and hemiparkinsonian rats.

  2017cites this paper
• Neonatal alcohol exposure reduces number of parvalbumin-positive interneurons in the medial prefrontal cortex and impairs passive avoidance acquisition in mice deficits not rescued from exercise.

  2017cites this paper
• Opioid neurotransmission modulates defensive behavior and fear-induced antinociception in dangerous environments.

  2017cites this paper
• Oxytocin in the medial prefrontal cortex attenuates anxiety: Anatomical and receptor specificity and mechanism of action.

  2017influential citation
• nxiolytic-like effect of hydrogen sulfide ( H 2 S ) in rats exposed and e-exposed to the elevated plus-maze and open field tests lberto

  2017cites this paper
• The ACC is a critical hub for neuropathic pain- induced depression

  2016cites this paper
• Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex.

  2016cites this paper
• Running Head: ANXIOLYTIC EFFECTS OF OT IN THE PRELIMBIC mPFC

  2015cites this paper
• Longitudinal assessment of infarct progression, brain metabolism and behavior following anterior cerebral artery occlusion in rats.

  2015cites this paper
• Medial prefrontal cortex serotonergic and GABAergic mechanisms modulate the expression of contextual fear: intratelencephalic pathways and differential involvement of cortical subregions.

  2015cites this paper
• Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex

  2015cites this paper
• A comparison of neural responses to appetitive and aversive stimuli in humans and other mammals.

  2014cites this paper
• Long-Term Behavioral Programming Induced by Peripuberty Stress in Rats Is Accompanied by GABAergic-Related Alterations in the Amygdala

  2014cites this paper
• D(1)-like receptors in the nucleus accumbens shell regulate the expression of contextual fear conditioning and activity of the anterior cingulate cortex in rats.

  2013influential citation
• 3, 4-methylenedioximethamphetamin reverses anxiety induced by chronic mild stress

  2013cites this paper
• Conditioned fear is modulated by CRF mechanisms in the periaqueductal gray columns.

  2013cites this paper
• Common brain activations for painful and non-painful aversive stimuli

  2012cites this paper
• Risk assessment behaviors associated with corticosterone trigger the defense reaction to social isolation in rats: Role of the anterior cingulate cortex

  2012cites this paper
• ERN and the placebo: a misattribution approach to studying the arousal properties of the error-related negativity.

  2012cites this paper
• L'anxiété liée au sevrage à la cocaïne : étude comportementale et neuroanatomique

  2012cites this paper
• Enhanced Anxiety Observed in Cocaine Withdrawn Rats Is Associated with Altered Reactivity of the Dorsomedial Prefrontal Cortex

  2012cites this paper
• Influence of age on reactivity to diverse emotional challenges in low‐ and high‐anxiety rats

  2011cites this paper
• Midazolam reduces the selective activation of the rhinal cortex by contextual fear stimuli.

  2011cites this paper
• Protein synthesis in dorsal hippocampus supports the drug tolerance induced by prior elevated plus-maze experience.

  2011cites this paper
• Identifying a Network of Brain Regions Involved in Aversion-Related Processing: A Cross-Species Translational Investigation

  2011cites this paper
• Hormonal and cognitive factors associated with the exploratory behavior of rats submitted to repeated sessions of the elevated plus-maze

  2010cites this paper
• Measuring behavior in mice with chronic stress depression paradigm.

  2010cites this paper
• GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure.

  2010cites this paper
• Activity in prelimbic cortex is required for adjusting the anxiety response level during the elevated plus-maze retest.

  2010cites this paper