Regulation of a disintegrins and metalloproteinase with thrombospondin motifs 7 during inflammation in nucleus pulposus (NP) cells: role of AP-1, Sp1 and NF-κB signaling

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Inflammation Research

• Publication date

  2016-08-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00011-016-0978-2PMID 27516213
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• SIRT1 expression is refractory to hypoxia and inflammatory cytokines in nucleus pulposus cells: Novel regulation by HIF‐1α and NF‐κB signaling

  2016cited by this paper
• Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition

  2015cited by this paper
• IL-17A enhances ADAMTS-7 expression through regulation of TNF-α in human nucleus pulposus cells

  2015cited by this paper
• Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3.

  2015cited by this paper
• Tumor necrosis factor alpha promotes the proliferation of human nucleus pulposus cells via nuclear factor-κB, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase

  2015cited by this paper
• Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration.

  2015cited by this paper
• Bone morphogenetic protein-7 antagonizes tumor necrosis factor-α-induced activation of nuclear factor κB and up-regulation of the ADAMTS, leading to decreased degradation of disc matrix macromolecules aggrecan and collagen II.

  2014cited by this paper
• Lack of Association between ABO, PPAP2B, ADAMST7, PIK3CG, and EDNRA and Carotid Intima-Media Thickness, Carotid Plaques, and Cardiovascular Disease in Patients with Rheumatoid Arthritis

  2014cited by this paper
• MicroRNA-122 Triggers Mesenchymal-Epithelial Transition and Suppresses Hepatocellular Carcinoma Cell Motility and Invasion by Targeting RhoA

  2014cited by this paper
• The regulation of hepcidin expression by serum treatment: requirements of the BMP response element and STAT- and AP-1-binding sites.

  2014cited by this paper
• Osteoarthritis: Positive feedback between ADAMTS-7 and TNF in OA

  2013influential reference
• The NF-κB signalling pathway in osteoarthritis.

  2013cited by this paper
• ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis

  2013influential reference
• Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration.

  2013cited by this paper
• Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.

  2013influential reference
• Transcription factors Sp1 and Sp3 regulate expression of human ABCG2 gene and chemoresistance phenotype

  2013cited by this paper
• Negative effects of ADAMTS‐7 and ADAMTS‐12 on endplate cartilage differentiation

  2012influential reference
• Expression of ADAMTS-7 and ADAMTS-12 in the nucleus pulposus during degeneration of rat caudal intervetebral disc.

  2012influential reference
• Regulation of CCN2/connective tissue growth factor expression in the nucleus pulposus of the intervertebral disc: role of Smad and activator protein 1 signaling.

  2010cited by this paper
• Matrix Metalloproteinase‐3 and Vitamin D Receptor Genetic Polymorphisms, and Their Interactions with Occupational Exposure in Lumbar Disc Degeneration

  2010cited by this paper
• Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues.

  2010cited by this paper
• Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis

  2009influential reference
• ADAMTS-7 Mediates Vascular Smooth Muscle Cell Migration and Neointima Formation in Balloon-Injured Rat Arteries

  2009influential reference
• Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation

  2009cited by this paper
• The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis

  2009cited by this paper
• Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration.

  2009cited by this paper
• BMP-2 and TGF-β Stimulate Expression of β1,3-Glucuronosyl Transferase 1 (GlcAT-1) in Nucleus Pulposus Cells Through AP1, TonEBP, and Sp1: Role of MAPKs

  2009cited by this paper
• Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin.

  2008cited by this paper
• Gene Expression Changes in an Early Stage of Intervertebral Disc Degeneration Induced by Passive Cigarette Smoking

  2006cited by this paper
• ADAMTS‐7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

  2006influential reference
• Specificity of transcriptional regulation by the zinc finger transcription factors Sp1, Sp3, and Egr‐1

  2005cited by this paper
• Sp1 and Sp3 Transcription Factors Mediate Interleukin-1β Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes*

  2003cited by this paper
• Oncoprotein c-Fos and c-Jun immunopositive cells and cell clusters in herniated intervertebral disc tissue

  2002cited by this paper
• Low back pain in relation to lumbar disc degeneration.

  2000cited by this paper
• ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc Metalloproteases

  1999cited by this paper
• Analysis of Aging and Degeneration of the Human Intervertebral Disc: Comparison of Surgical Specimens With Normal Controls

  1998cited by this paper
• C-Jun and JunD suppress maturation of chondrocytes.

  1997cited by this paper
• Disc Degeneration Affects the Multidirectional Flexibility of the Lumbar Spine

  1994cited by this paper

• Direct Oral Anticoagulant-Related Bleeding in Atrial Fibrillation Patients Leads to ADAMTS7 Promoter Demethylation

  2025cites this paper
• Cellular senescence - Molecular mechanisms of intervertebral disc degeneration from an immune perspective.

  2023cites this paper
• Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration

  2023cites this paper
• The Proteolysis of ECM in Intervertebral Disc Degeneration

  2022cites this paper
• Nicotinamide Phosphoribosyl Transferase Controls NLRP3 Inflammasome Activity Through MAPK and NF-κB Signaling in Nucleus Pulposus Cells, as Suppressed by Melatonin

  2020cites this paper
• The role of IL-1β and TNF-α in intervertebral disc degeneration.

  2020cites this paper
• Identification of cardiovascular health gene variants related to longevity in a Chinese population

  2020cites this paper
• MicroRNA‐145 overexpression attenuates apoptosis and increases matrix synthesis in nucleus pulposus cells

  2019cites this paper
• Moderate Fluid Shear Stress Could Regulate the Cytoskeleton of Nucleus Pulposus and Surrounding Inflammatory Mediators by Activating the FAK-MEK5-ERK5-cFos-AP1 Signaling Pathway

  2018cites this paper
• MicroRNA-155 suppresses the catabolic effect induced by TNF-α and IL-1β by targeting C/EBPβ in rat nucleus pulposus cells

  2018cites this paper
• Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells.

  2018cites this paper
• Corrigendum to “Moderate Fluid Shear Stress Could Regulate the Cytoskeleton of Nucleus Pulposus and Surrounding Inflammatory Mediators by Activating the FAK-MEK5-ERK5-cFos-AP1 Signaling Pathway”

  2018cites this paper
• SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models.

  2018cites this paper
• The PI3K/Akt pathway: a critical player in intervertebral disc degeneration

  2017cites this paper